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Results for “pMMR/MSS Advanced Colorectal Cancer”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07359456
What this trial is testing

Testing Ivonescimab in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancers Without Liver Metastases

Who this might be right for
Metastatic Colorectal Cancer
UNICANCER 130
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06391905
What this trial is testing

PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS

Who this might be right for
Colorectal Cancer
Guangdong Provincial People's Hospital 60
Testing effectiveness (Phase 2)Looking for participantsNCT07644286
What this trial is testing

A Phase II Study of Pirfenidone Plus PD-1 Inhibitor With or Without Hypofractionated Radiotherapy for Refractory pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Tao Zhang 48
Testing effectiveness (Phase 2)Looking for participantsNCT07079631
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BioNTech SE 482
Testing effectiveness (Phase 2)Looking for participantsNCT06709885
What this trial is testing

HDAC Inhibitor Combination With Chemoimmunotherapy in the Neoadjuvant Treatment of pMMR Locally Advanced Colon Cancer

Who this might be right for
Colon Adenocarcinoma
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 100
Testing effectiveness (Phase 2)Looking for participantsNCT06885385
What this trial is testing

Study Evaluating the Safety and Efficacy of JS207 With or Without JS015 in Combination With Chemotherapy in Patients With Colorectal Cancer

Who this might be right for
Advanced Colorectal Cancer
Shanghai Junshi Bioscience Co., Ltd. 60
Early research (Phase 1)Looking for participantsNCT07510308
What this trial is testing

Clinical Study of MSH2-/- Tumor Cell Vaccines for Advanced pMMR Colorectal Cancer Patients

Who this might be right for
pMMR/MSS Advanced Colorectal Cancer
West China Hospital 9
Large-scale testing (Phase 3)Not Yet RecruitingNCT07595276
What this trial is testing

Comparing Efficacy and Safety of Enlituo® Versus Erbitux® Plus FOLFOX in Locally Advanced/Metastatic Colorectal Cancer With RAS/BRAF Wild-type and MSS/pMMR Status.

Who this might be right for
Colorectal Cancer
Taizhou Mabtech Pharmaceutical Co.,Ltd 608
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06014944
What this trial is testing

Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody

Who this might be right for
Rectal Cancer
Changhai Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07622771
What this trial is testing

Neoadjuvant Radiotherapy Combined With NALIRIFOX and Adebrelimab in pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Randomized, Phase II Clinical Trial

Who this might be right for
Rectal Cancers
Sun Yat-sen University 84
Post-approval studies (Phase 4)Not Yet RecruitingNCT07446465
What this trial is testing

FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer (Locally Advanced or Metastatic)Colorectal Cancer Microsatellite Stable (MSS)
Ye Xu 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381400
What this trial is testing

Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study)

Who this might be right for
Rectal Cancer
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 128
Testing effectiveness (Phase 2)Looking for participantsNCT06949111
What this trial is testing

Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color）

Who this might be right for
Colon Cancer
Hebei Medical University Fourth Hospital 128
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07765667
What this trial is testing

NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC

Who this might be right for
Rectal AdenocarcinomaHigh-Risk CancerMSS
Sixth Affiliated Hospital, Sun Yat-sen University 100
Testing effectiveness (Phase 2)Looking for participantsNCT06923345
What this trial is testing

Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 80
Not applicableEnrolling By InvitationNCT06936488
What this trial is testing

A Prospective, Single Arm, Open Label, Phase II Clinical Study on the Efficacy and Safety of Ivonescimab (AK112) Combined With TAS-102 in the Treatment of Refractory MSS/pMMR Advanced Colorectal Cancer

Who this might be right for
MSS/pMMR Type Metastatic Colorectal Adenocarcinoma Patients
Huai'an First People's Hospital 35
Testing effectiveness (Phase 2)Looking for participantsNCT06911684
What this trial is testing

Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.

Who this might be right for
Rectal Cancer Patients
Sun Yat-sen University 88
Testing effectiveness (Phase 2)UnknownNCT05815303
What this trial is testing

XELOX Combined With Cadonilimab Versus XELOX as Neoadjuvant Treatment for Locally Advanced, pMMR Rectal Cancer

Who this might be right for
Rectal CancerMSS
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 92
Not applicableEnrolling By InvitationNCT06849362
What this trial is testing

Multicenter Retrospective Study on Optimizing Combination Immunotherapy Strategies in MSS/MSI-L/pMMR Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer (CRC)MSS Metastatic Colorectal CancerImmunotherapy
Yue Gou 200
Testing effectiveness (Phase 2)Looking for participantsNCT07106034
What this trial is testing

Standard Second-line Therapy With ONgericimab and TOripalimab in pMMR/MSS Colorectal Cancer: a Single-arm Phase II Trial

Who this might be right for
Advanced Colorectal Cancer
Shanghai Pudong Hospital 32
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