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Results for “Ammonia; Metabolic Disorder”

23 trials

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Showing 20 of 23 results

Large-scale testing (Phase 3)WithdrawnNCT04128462
What this trial is testing

MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function

Who this might be right for
Hepatic Encephalopathy
Mallinckrodt
Not applicableEnrolling By InvitationNCT06953505
What this trial is testing

At Home Ammonia Monitoring of Inborn Errors of Ammonia Metabolism

Who this might be right for
Urea Cycle DisordersOrganic AcidemiasFatty Acid Oxidation Disorder+1 more
Sequitur Health Corp. 30
Not applicableUnknownNCT04585672
What this trial is testing

Ammonia Metabolism Assessed by Ammonia Infusion

Who this might be right for
Ammonia; Metabolic DisorderLiver Failure, Chronic
Aarhus University Hospital 20
Not applicableStudy completedNCT00424957
What this trial is testing

Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System

Who this might be right for
CirrhosisHepatic Encephalopathy
University of Aarhus 18
Not applicableLooking for participantsNCT06805695
What this trial is testing

Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseUrea Cycle Disorders, Inborn
iECURE, Inc. 13
Not applicableStudy completedNCT03797131
What this trial is testing

Clinical Food Study to Evaluate the Effect of KB195 on Gut Nitrogen Metabolism in Patients With Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Kaleido Biosciences 4
Testing effectiveness (Phase 2)Ended earlyNCT06987968
What this trial is testing

See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy

Who this might be right for
Hepatic EncephalopathyAcute on Chronic Liver Failure (ACLF)Decompensated Cirrhosis
Genfit 3
Testing effectiveness (Phase 2)UnknownNCT02334163
What this trial is testing

The Effects of Nitazoxanide in Hepatic Encephalopathy

Who this might be right for
Hepatic Encephalopathy
Ain Shams University 36
Not applicableStudy completedNCT05376488
What this trial is testing

Effect of Brief Dietary Intervention on Ammonia Levels

Who this might be right for
CirrhosisHepatic Encephalopathy
Hunter Holmes Mcguire Veteran Affairs Medical Center 30
Not applicableEnrolling By InvitationNCT06987604
What this trial is testing

Continuous Renal Replacement Therapy Intensity in Hyperammonemia

Who this might be right for
Acute Liver FailureAcute on Chronic Liver Failure (ACLF)Acute Kidney Injury+1 more
Hospital de Clinicas de Porto Alegre 152
Post-approval studies (Phase 4)Study completedNCT03335488
What this trial is testing

Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders (UCDs)

Who this might be right for
Urea Cycle Disorder
Amgen 16
Testing effectiveness (Phase 2)Study completedNCT01624311
What this trial is testing

Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants

Who this might be right for
Urea Cycle DisordersOrganic Acidemias
Uta Lichter-Konecki 5
Not applicableStudy completedNCT00931060
What this trial is testing

Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects

Who this might be right for
Liver DiseasesHepatic EncephalopathyHepatic Insufficiency
University of Aarhus 24
Not applicableStudy completedNCT01151475
What this trial is testing

Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE)

Who this might be right for
Liver CirrhosisHepatic Encephalopathy
University of Aarhus 10
Testing effectiveness (Phase 2)Looking for participantsNCT06255782
What this trial is testing

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseOrnithine Carbamoyltransferase Deficiency (Disorder)+1 more
iECURE, Inc. 8
Not applicableStudy completedNCT00312910
What this trial is testing

Probiotics for the Prevention of Major Complications of Cirrhosis

Who this might be right for
Liver Cirrhosis
Meir Medical Center 50
Not applicableStudy completedNCT04269122
What this trial is testing

Assess Plasma Ammonia Time-Normalized Area Under the Curve and Rate of Ureagenesis in Healthy Adult Subjects

Who this might be right for
Ornithine Transcarbamylase Deficiency
Ultragenyx Pharmaceutical Inc 120
Not applicableEnded earlyNCT01948427
What this trial is testing

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs)

Who this might be right for
Urea Cycle Disorder
Amgen 203
Not applicableStudy completedNCT00472732
What this trial is testing

Neurologic Injuries in Adults With Urea Cycle Disorders

Who this might be right for
Brain Diseases, Metabolic, InbornUrea Cycle DisorderOrnithine Transcarbamylase Deficiency
Andrea Gropman 46
Not applicableUnknownNCT05421351
What this trial is testing

Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLF

Who this might be right for
Hepatic EncephalopathyAcute-On-Chronic Liver FailureDecompensated Cirrhosis
Post Graduate Institute of Medical Education and Research, Chandigarh 135
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