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Results for “Autologous CD19 CAR-T”

129 trials

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Showing 20 of 129 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT07493395
What this trial is testing

Phase IIa Trial of Anti-CD19 CAR T-Cells in Systemic Sclerosis Resistant to Immunosuppressive Therapy

Who this might be right for
Scleroderma, Systemic
University Hospital, Montpellier 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT03573700
What this trial is testing

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, Refractory
St. Jude Children's Research Hospital 24
Early research (Phase 1)Looking for participantsNCT07361094
What this trial is testing

Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory Systemic Lupus ErythematosusRelapsed/Refractory Systemic SclerosisRelapsed/Refractory Idiopathic Inflammatory Myopathies+3 more
Beijing Boren Hospital 12
Testing effectiveness (Phase 2)Ended earlyNCT05938725
What this trial is testing

KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Who this might be right for
Lupus NephritisLupus Nephritis - World Health Organization (WHO) Class IIILupus Nephritis - WHO Class IV
Kyverna Therapeutics 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT06384976
What this trial is testing

KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary ProgressiveMultiple Sclerosis, Secondary ProgressiveMultiple Sclerosis+1 more
Kyverna Therapeutics 120
Not applicableLooking for participantsNCT07052565
What this trial is testing

CAR-T Cells Therapy for Patients With Autoimmune Diseases

Who this might be right for
Autoimmune Diseases
Anhui Provincial Hospital 18
Very early researchUnknownNCT05239676
What this trial is testing

Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Refractory and Relapsed Malignant Lymphoma

Who this might be right for
Lymphoma
Zhejiang University 50
Early research (Phase 1)Looking for participantsNCT06710717
What this trial is testing

Autologous CD19 Car T-Cell Therapy For Severe Refractory Systemic Lupus Erythematosus (SLE)

Who this might be right for
Systemic Lupus Erythematous (SLE)
National University of Malaysia 5
Early research (Phase 1)Looking for participantsNCT05432635
What this trial is testing

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

Who this might be right for
B-Cell Non-Hodgkin LymphomaDiffuse Large B-Cell LymphomaMantle Cell Lymphoma+5 more
City of Hope Medical Center 15
Early research (Phase 1)Active Not RecruitingNCT06231368
What this trial is testing

CNCT19 for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.

Who this might be right for
Autoimmune Hemolytic AnemiaAutologous CD19 CAR-TFailure of Three or More Lines of Therapy
Institute of Hematology & Blood Diseases Hospital, China 6
Testing effectiveness (Phase 2)Looking for participantsNCT06121297
What this trial is testing

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus ErythematosusLupus Nephritis
Cabaletta Bio 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07659704
What this trial is testing

CD19-Directed CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus

Who this might be right for
Lupus Erythematosus, Systemic
University of Sao Paulo 16
Large-scale testing (Phase 3)Looking for participantsNCT07502118
What this trial is testing

NexCAR19 (Talikabtagene Autoleucel) in Relapsed/Refractory B-Cell Malignancies (NexCAR19)

Who this might be right for
Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia (B-ALL)Relapsed/Refractory Non-Hodgkin LymphomaDiffuse Large B-Cell Lymphoma (DLBCL)+2 more
Health Institutes of Turkey 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT05421663
What this trial is testing

JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Who this might be right for
Lymphoma, Non-HodgkinLymphoma, B-CellLymphoma, Large B-Cell, Diffuse
Janssen Research & Development, LLC 166
Testing effectiveness (Phase 2)Looking for participantsNCT05480449
What this trial is testing

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

Who this might be right for
B Cell Acute Lymphoblastic Leukemia (B-ALL)B Lineage Lymphoblastic Lymphoma
Stephan Grupp MD PhD 115
Not applicableLooking for participantsNCT06961669
What this trial is testing

Intravenous Autologous CD19 CAR-T Cells for R/ R MM, B-ALL, and B-Cell Lymphoma

Who this might be right for
Lymphoblastic LeukemiaRelapsed or Refractory Multiple Myeloma (RRMM)
Anhui Provincial Hospital 18
Early research (Phase 1)Ended earlyNCT04049383
What this trial is testing

CAR-20/19-T Cells in Patients With Relapsed/Refractory B Cell ALL

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia With Failed RemissionAcute Lymphoblastic Leukemia Recurrent+3 more
Medical College of Wisconsin 5
Very early researchEnded earlyNCT06462144
What this trial is testing

IMPT-514 in Systemic Lupus Erythematosus, Anca-associated Vasculitis, and Idiopathic Inflammatory Myopathy

Who this might be right for
Systemic Lupus Erythematosus (SLE)ANCA Associated Vasculitis (AAV)Idiopathic Inflammatory Myopathy (IIM)
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 3
Testing effectiveness (Phase 2)Looking for participantsNCT05674175
What this trial is testing

Co-administration of CART22-65s and huCART19 for B-ALL

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaB Lineage Lymphoblastic Lymphoma
Stephan Grupp MD PhD 93
Testing effectiveness (Phase 2)Ended earlyNCT05972720
What this trial is testing

Firi-cel in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
CancerRelapsed/Refractory Large B-cell Lymphoma (LBCL)
CARGO Therapeutics 101
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