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Results for “Autologous CD19 CAR-T”

124 trials

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Showing 20 of 124 results

Testing effectiveness (Phase 2)Looking for participantsNCT06378190
What this trial is testing

Treatment of Relapsed or Refractory B-cell Lymphoma With Chimeric Antigen Receptor (CAR) T-cell Therapy Produced by a New Technology

Who this might be right for
Refractory B-Cell LymphomaB-cell Lymphoma Recurrent
Instituto de Investigación Biomédica de Salamanca 27
Early research (Phase 1)Looking for participantsNCT07224373
What this trial is testing

An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
AstraZeneca 24
Large-scale testing (Phase 3)Ended earlyNCT05664217
What this trial is testing

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaRelapsed/Refractory Diffuse Large B-cell Lymphoma
Nektar Therapeutics 15
Testing effectiveness (Phase 2)Looking for participantsNCT04422912
What this trial is testing

A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

Who this might be right for
Pemphigus Vulgaris
Cabaletta Bio 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05091541
What this trial is testing

CT120 in Patient With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Who this might be right for
B-cell Non-Hodgkin's Lymphoma
Nanjing IASO Biotechnology Co., Ltd. 125
Very early researchUnknownNCT05239676
What this trial is testing

Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Refractory and Relapsed Malignant Lymphoma

Who this might be right for
Lymphoma
Zhejiang University 50
Testing effectiveness (Phase 2)UnknownNCT02134262
What this trial is testing

Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes

Who this might be right for
Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Jichi Medical University 18
Early research (Phase 1)Active Not RecruitingNCT01683279
What this trial is testing

A Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
B Cell Leukemia
Seattle Children's Hospital 6
Early research (Phase 1)Active Not RecruitingNCT06231368
What this trial is testing

CNCT19 for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.

Who this might be right for
Autoimmune Hemolytic AnemiaAutologous CD19 CAR-TFailure of Three or More Lines of Therapy
Institute of Hematology & Blood Diseases Hospital, China 6
Testing effectiveness (Phase 2)Looking for participantsNCT04989803
What this trial is testing

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

Who this might be right for
Relapsed and/or Refractory B-cell Lymphoma
Kite, A Gilead Company 247
Early research (Phase 1)Active Not RecruitingNCT01840566
What this trial is testing

High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma

Who this might be right for
Non-Hodgkin's Lymphoma
Memorial Sloan Kettering Cancer Center 17
Early research (Phase 1)Ended earlyNCT04160195
What this trial is testing

T Cells Expressing Fully-human Anti-CD19 and Anti-CD20 Chimeric Antigen Receptors for Treating B-cell Malignancies and Hodgkin Lymphoma

Who this might be right for
Lymphoma, B-CellLymphoma, Non-hodgkinsChronic Lymphocytic Leukemia+1 more
National Cancer Institute (NCI) 2
Testing effectiveness (Phase 2)Looking for participantsNCT05850234
What this trial is testing

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

Who this might be right for
Relapsed/Refractory Multiple Myeloma
AstraZeneca 182
Testing effectiveness (Phase 2)Active Not RecruitingNCT05470777
What this trial is testing

CD22/CD19 CAR-T and Auto-HSCT Sandwich Strategy as Consolidation Therapy for B-ALL

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
The First Affiliated Hospital of Soochow University 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT06342960
What this trial is testing

KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Who this might be right for
Lupus NephritisLupus Nephritis - WHO Class IIILupus Nephritis - WHO Class IV
Kyverna Therapeutics 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT05938725
What this trial is testing

KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Who this might be right for
Lupus NephritisLupus Nephritis - World Health Organization (WHO) Class IIILupus Nephritis - WHO Class IV
Kyverna Therapeutics 6
Early research (Phase 1)Looking for participantsNCT07295847
What this trial is testing

AZD0120 in Autoimmune Diseases

Who this might be right for
Systemic SclerosisIdiopathic Inflammatory MyopathiesRheumatoid Arthritis
AstraZeneca 27
Early research (Phase 1)Looking for participantsNCT06710717
What this trial is testing

Autologous CD19 Car T-Cell Therapy For Severe Refractory Systemic Lupus Erythematosus (SLE)

Who this might be right for
Systemic Lupus Erythematous (SLE)
National University of Malaysia 5
Early research (Phase 1)Looking for participantsNCT05963217
What this trial is testing

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

Who this might be right for
Relapsed or Refractory CD19+ B-cell LymphomaRelapsed or Refractory Chronic Lymphocytic LeukemiaRelapsed or Refractory Small Lymphocytic Lymphoma
University Health Network, Toronto 19
Testing effectiveness (Phase 2)Study completedNCT04325841
What this trial is testing

Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children

Who this might be right for
Acute Lymphoblastic Leukemia, PediatricAcute Lymphoblastic Leukemia, in RelapseRefractory Acute Lymphoblastic Leukemia
Beijing Boren Hospital 2
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