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Results for “C-KIT Mutation”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Study completedNCT01028222
What this trial is testing

AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation

Who this might be right for
Melanoma
Novartis Pharmaceuticals 55
Not applicableStudy completedNCT02503800
What this trial is testing

The Significance of Blood-tryptase and c-Kit Mutation in Insect Venom Immunotherapy

Who this might be right for
Hypersensitivity, ImmediateInsect Bites and StingsMastocytosis
Meir Medical Center 159
Large-scale testing (Phase 3)Ended earlyNCT01280565
What this trial is testing

Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit

Who this might be right for
Metastatic Melanoma
AB Science 134
Testing effectiveness (Phase 2)Looking for participantsNCT06316960
What this trial is testing

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

Who this might be right for
AML, ChildhoodRelapse/RecurrenceRefractory AML+2 more
Children's Hospital of Soochow University 50
Large-scale testing (Phase 3)Study completedNCT00814073
What this trial is testing

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis

Who this might be right for
Indolent Systemic Mastocytosis
AB Science 135
Testing effectiveness (Phase 2)Study completedNCT00171912
What this trial is testing

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Who this might be right for
Hypereosinophilic SyndromeSystemic MastocytosisChronic Myelomonocytic Leukemia+1 more
Novartis Pharmaceuticals 38
Testing effectiveness (Phase 2)Study completedNCT01266369
What this trial is testing

Masitinib in Patients With Mastocytosis With Handicap and Bearing the D816V Mutation

Who this might be right for
Mastocytosis
AB Science 21
Testing effectiveness (Phase 2)Study completedNCT01395121
What this trial is testing

A Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has Spread

Who this might be right for
Mucosal Lentiginous MelanomaAcral Lentiginous Malignant Melanoma
Institute of Cancer Research, United Kingdom 29
Not applicableStudy completedNCT00336076
What this trial is testing

Molecular Mechanisms and Diagnosis of Mastocytosis

Who this might be right for
Mastocytosis
University of Michigan 136
Not applicableStudy completedNCT01505205
What this trial is testing

Study on the Evolution of Genes Mutation Related With Gastrointestinal Stromal Tumors

Who this might be right for
Full Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing ApproachInvestigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients
Guangxi Medical University 60
Testing effectiveness (Phase 2)Study completedNCT02606097
What this trial is testing

Regorafenib in GIST With Secondary C-KIT Exon 17 Mutation

Who this might be right for
Gastrointestinal Stromal Tumour (GIST)
Chang Gung Memorial Hospital 19
Testing effectiveness (Phase 2)UnknownNCT03171389
What this trial is testing

POETIG Trial - POnatinib After rEsisTance to Imatinib in GIST

Who this might be right for
GIST, MalignantKIT Exon 13 MutationKIT Gene Mutation
Sebastian Bauer 81
Testing effectiveness (Phase 2)Study completedNCT00831974
What this trial is testing

Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis

Who this might be right for
Mastocytosis
AB Science 23
Testing effectiveness (Phase 2)Looking for participantsNCT05009927
What this trial is testing

Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten)

Who this might be right for
Metastatic Gastrointestinal Stromal Tumor (GIST)C-KIT MutationAdvanced Gastrointestinal Stromal Tumor (GIST)
Centre Leon Berard 50
Testing effectiveness (Phase 2)UnknownNCT02501551
What this trial is testing

Regorafenib, C-kit Mutated Malignant Melanoma, 2nd Line Therapy

Who this might be right for
Melanoma
Yonsei University 36
Testing effectiveness (Phase 2)Looking for participantsNCT07559864
What this trial is testing

Comparing Regorafenib Combined With Envafolimab to Physician's Choice in Patients With Metastatic Gastrointestinal Stromal Tumors Harboring KIT Exon 17 Mutations Refractory to Standard Treatment

Who this might be right for
GIST - Gastrointestinal Stromal TumorKIT Gene Mutation
Jian Li 100
Testing effectiveness (Phase 2)Study completedNCT00278876
What this trial is testing

Adjuvant Imatinib in High-risk Gastrointestinal Stromal Tumor (GIST) With C-kit Mutation

Who this might be right for
SarcomaGastrointestinal Stromal Tumors
Asan Medical Center 47
Testing effectiveness (Phase 2)Study completedNCT00782067
What this trial is testing

Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia

Who this might be right for
Leukemia
Novartis Pharmaceuticals 116
Testing effectiveness (Phase 2)Study completedNCT00881049
What this trial is testing

Trial of Imatinib (Gleevec®) in Selected Patients With Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Peking University 1
Early research (Phase 1)WithdrawnNCT03560908
What this trial is testing

Dasatinib Combined With Chemotherapy in Relapsed t(8;21) Acute Myeloid Leukemia With KIT D816 Mutation

Who this might be right for
Relapsed AMLT(8;21)C-KIT Mutation
Institute of Hematology & Blood Diseases Hospital, China
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