Testing effectiveness (Phase 2)UnknownNCT02501551What this trial is testingRegorafenib, C-kit Mutated Malignant Melanoma, 2nd Line TherapyWho this might be right forMelanoma Yonsei University 36
Testing effectiveness (Phase 2)Study completedNCT00171912What this trial is testingImatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase EnzymesWho this might be right forHypereosinophilic SyndromeSystemic MastocytosisChronic Myelomonocytic Leukemia+1 more Novartis Pharmaceuticals 38
Testing effectiveness (Phase 2)Looking for participantsNCT05009927What this trial is testingEfficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten)Who this might be right forMetastatic Gastrointestinal Stromal Tumor (GIST)C-KIT MutationAdvanced Gastrointestinal Stromal Tumor (GIST) Centre Leon Berard 50
Testing effectiveness (Phase 2)WithdrawnNCT02812693What this trial is testingPembrolizumab and Imatinib in Patients With Locally Advanced/Metastatic Melanoma With c-KIT Mutation/AmplificationWho this might be right forStage IIIA Skin MelanomaStage IIIB Skin MelanomaStage IIIC Skin Melanoma+1 more Joanne Jeter
Large-scale testing (Phase 3)Study completedNCT00814073What this trial is testingMasitinib in Severe Indolent or Smoldering Systemic MastocytosisWho this might be right forIndolent Systemic Mastocytosis AB Science 135
Testing effectiveness (Phase 2)Study completedNCT00881049What this trial is testingTrial of Imatinib (Gleevec®) in Selected Patients With Metastatic MelanomaWho this might be right forMetastatic Melanoma Peking University 1
Testing effectiveness (Phase 2)UnknownNCT03171389What this trial is testingPOETIG Trial - POnatinib After rEsisTance to Imatinib in GISTWho this might be right forGIST, MalignantKIT Exon 13 MutationKIT Gene Mutation Sebastian Bauer 81
Testing effectiveness (Phase 2)Study completedNCT00831974What this trial is testingEfficacy of AB1010 in Patients With Systemic Indolent MastocytosisWho this might be right forMastocytosis AB Science 23
Testing effectiveness (Phase 2)Study completedNCT01028222What this trial is testingAMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit MutationWho this might be right forMelanoma Novartis Pharmaceuticals 55
Testing effectiveness (Phase 2)Study completedNCT01266369What this trial is testingMasitinib in Patients With Mastocytosis With Handicap and Bearing the D816V MutationWho this might be right forMastocytosis AB Science 21
Not applicableStudy completedNCT00336076What this trial is testingMolecular Mechanisms and Diagnosis of MastocytosisWho this might be right forMastocytosis University of Michigan 136
Testing effectiveness (Phase 2)Study completedNCT01395121What this trial is testingA Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has SpreadWho this might be right forMucosal Lentiginous MelanomaAcral Lentiginous Malignant Melanoma Institute of Cancer Research, United Kingdom 29
Large-scale testing (Phase 3)Study completedNCT02260505What this trial is testingEfficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)Who this might be right forGastrointestinal Stromal TumorsResected Gastrointestinal Stromal TumorsNon-metastatic+2 more Centre Leon Berard 136
Testing effectiveness (Phase 2)Study completedNCT02606097What this trial is testingRegorafenib in GIST With Secondary C-KIT Exon 17 MutationWho this might be right forGastrointestinal Stromal Tumour (GIST) Chang Gung Memorial Hospital 19
Large-scale testing (Phase 3)Ended earlyNCT01280565What this trial is testingMasitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-KitWho this might be right forMetastatic Melanoma AB Science 134
Testing effectiveness (Phase 2)Looking for participantsNCT07559864What this trial is testingComparing Regorafenib Combined With Envafolimab to Physician's Choice in Patients With Metastatic Gastrointestinal Stromal Tumors Harboring KIT Exon 17 Mutations Refractory to Standard TreatmentWho this might be right forGIST - Gastrointestinal Stromal TumorKIT Gene Mutation Jian Li 100
Testing effectiveness (Phase 2)UnknownNCT01168050What this trial is testingEfficacy of Nilotinib in First or Second Line Treatment of Primary Melanomas Stage III Unresectable Melanomas.Who this might be right forMalignant Skin Melanoma T0Stage III MelanomaStage IV Melanoma+1 more Assistance Publique - Hôpitaux de Paris 25
Not applicableStudy completedNCT02503800What this trial is testingThe Significance of Blood-tryptase and c-Kit Mutation in Insect Venom ImmunotherapyWho this might be right forHypersensitivity, ImmediateInsect Bites and StingsMastocytosis Meir Medical Center 159
Testing effectiveness (Phase 2)Study completedNCT01830361What this trial is testingTrial to Assess the Efficacy of Midostaurin (PKC412) in Patients With c-KIT or FLT3-ITD Mutated t(8;21) AMLWho this might be right forAcute Myeloid Leukemia Technische Universität Dresden 18
Not applicableWithdrawnNCT06116318What this trial is testingC-Kit Mutation as MRD in Acute Myeloid LeukemiaWho this might be right forC-KIT Mutation Institute of Hematology & Blood Diseases Hospital, China