Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “C-KIT Mutation”

27 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 27 results

Testing effectiveness (Phase 2)Looking for participantsNCT06316960
What this trial is testing

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

Who this might be right for
AML, ChildhoodRelapse/RecurrenceRefractory AML+2 more
Children's Hospital of Soochow University 50
Testing effectiveness (Phase 2)WithdrawnNCT02812693
What this trial is testing

Pembrolizumab and Imatinib in Patients With Locally Advanced/Metastatic Melanoma With c-KIT Mutation/Amplification

Who this might be right for
Stage IIIA Skin MelanomaStage IIIB Skin MelanomaStage IIIC Skin Melanoma+1 more
Joanne Jeter
Testing effectiveness (Phase 2)Study completedNCT00782067
What this trial is testing

Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia

Who this might be right for
Leukemia
Novartis Pharmaceuticals 116
Testing effectiveness (Phase 2)Looking for participantsNCT05009927
What this trial is testing

Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten)

Who this might be right for
Metastatic Gastrointestinal Stromal Tumor (GIST)C-KIT MutationAdvanced Gastrointestinal Stromal Tumor (GIST)
Centre Leon Berard 50
Large-scale testing (Phase 3)Study completedNCT00814073
What this trial is testing

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis

Who this might be right for
Indolent Systemic Mastocytosis
AB Science 135
Large-scale testing (Phase 3)Ended earlyNCT01280565
What this trial is testing

Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit

Who this might be right for
Metastatic Melanoma
AB Science 134
Not applicableLooking for participantsNCT06116318
What this trial is testing

C-Kit Mutation as MRD in Acute Myeloid Leukemia

Who this might be right for
C-KIT Mutation
Institute of Hematology & Blood Diseases Hospital, China 50
Testing effectiveness (Phase 2)Looking for participantsNCT07028073
What this trial is testing

A New Treatment of Newly Diagnosed KIT Mutation CBF-Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With T(8;21)(Q22;Q22)Acute Myeloid Leukemia With T(16;16)(P13;Q22)KIT Gene Mutation+1 more
The First Affiliated Hospital of Soochow University 78
Not applicableStudy completedNCT02503800
What this trial is testing

The Significance of Blood-tryptase and c-Kit Mutation in Insect Venom Immunotherapy

Who this might be right for
Hypersensitivity, ImmediateInsect Bites and StingsMastocytosis
Meir Medical Center 159
Testing effectiveness (Phase 2)Study completedNCT00171912
What this trial is testing

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Who this might be right for
Hypereosinophilic SyndromeSystemic MastocytosisChronic Myelomonocytic Leukemia+1 more
Novartis Pharmaceuticals 38
Testing effectiveness (Phase 2)Study completedNCT01028222
What this trial is testing

AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation

Who this might be right for
Melanoma
Novartis Pharmaceuticals 55
Not applicableUnknownNCT01227746
What this trial is testing

A Retrospective Study of C-kit Mutation Status in Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib.

Who this might be right for
Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib
National University Hospital, Singapore
Early research (Phase 1)WithdrawnNCT03560908
What this trial is testing

Dasatinib Combined With Chemotherapy in Relapsed t(8;21) Acute Myeloid Leukemia With KIT D816 Mutation

Who this might be right for
Relapsed AMLT(8;21)C-KIT Mutation
Institute of Hematology & Blood Diseases Hospital, China
Testing effectiveness (Phase 2)Study completedNCT00881049
What this trial is testing

Trial of Imatinib (Gleevec®) in Selected Patients With Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Peking University 1
Testing effectiveness (Phase 2)Study completedNCT00278876
What this trial is testing

Adjuvant Imatinib in High-risk Gastrointestinal Stromal Tumor (GIST) With C-kit Mutation

Who this might be right for
SarcomaGastrointestinal Stromal Tumors
Asan Medical Center 47
Large-scale testing (Phase 3)Study completedNCT02260505
What this trial is testing

Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)

Who this might be right for
Gastrointestinal Stromal TumorsResected Gastrointestinal Stromal TumorsNon-metastatic+2 more
Centre Leon Berard 136
Testing effectiveness (Phase 2)UnknownNCT02501551
What this trial is testing

Regorafenib, C-kit Mutated Malignant Melanoma, 2nd Line Therapy

Who this might be right for
Melanoma
Yonsei University 36
Testing effectiveness (Phase 2)Study completedNCT00831974
What this trial is testing

Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis

Who this might be right for
Mastocytosis
AB Science 23
Not applicableStudy completedNCT01505205
What this trial is testing

Study on the Evolution of Genes Mutation Related With Gastrointestinal Stromal Tumors

Who this might be right for
Full Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing ApproachInvestigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients
Guangxi Medical University 60
Testing effectiveness (Phase 2)Study completedNCT01830361
What this trial is testing

Trial to Assess the Efficacy of Midostaurin (PKC412) in Patients With c-KIT or FLT3-ITD Mutated t(8;21) AML

Who this might be right for
Acute Myeloid Leukemia
Technische Universität Dresden 18
Load More Results