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Results for “Depressive Disorder, Treatment Resistant”

680 trials

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Showing 20 of 680 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07227103
What this trial is testing

A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial

Who this might be right for
Treatment Resistant DepressionTreatment Resistant Depression (TRD)
NeuroRx, Inc. 400
Not applicableLooking for participantsNCT03952962
What this trial is testing

Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

Who this might be right for
Treatment Resistant DepressionUndergoing Deep Brain Stimulation (DBS) Surgery
Nader Pouratian 12
Not applicableLooking for participantsNCT05418894
What this trial is testing

Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing

Who this might be right for
Treatment Resistant DepressionEpilepsy
Baylor College of Medicine 84
Testing effectiveness (Phase 2)Study completedNCT06620042
What this trial is testing

FMRI of Patients Receiving IV Ketamine for Treatment Resistant Bipolar Depression

Who this might be right for
Bipolar DepressionTreatment Resistant Bipolar Depression
Brian Barnett 20
Testing effectiveness (Phase 2)Looking for participantsNCT06524830
What this trial is testing

Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

Who this might be right for
Treatment Resistant Depression
atai Therapeutics, Inc. 142
Post-approval studies (Phase 4)Study completedNCT04727229
What this trial is testing

Stellate Ganglion Block for Major Depressive Disorder.

Who this might be right for
Treatment Resistant DepressionMajor Depressive Disorder
Unity Health Toronto 10
Large-scale testing (Phase 3)WithdrawnNCT04924257
What this trial is testing

ECT vs. Esketamine

Who this might be right for
Treatment Resistant DepressionMajor Depressive Disorder
Medical University Innsbruck
Testing effectiveness (Phase 2)UnknownNCT01868802
What this trial is testing

Ketamine for Treatment-resistant Depression: A Multicentric Clinical Trial in Mexican Population

Who this might be right for
Depressive Disorder,Treatment-Resistant Depression
Paul J. Lamothe 60
Large-scale testing (Phase 3)Study completedNCT00789854
What this trial is testing

Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients

Who this might be right for
Major Depressive DisorderTreatment Resistant Depression
AstraZeneca 688
Large-scale testing (Phase 3)Looking for participantsNCT07088380
What this trial is testing

Ketamine Augmentation of ECT in Treatment-Resistant Depression

Who this might be right for
Major Depressive DisorderTreatment Resistant Depression
Università Vita-Salute San Raffaele 30
Very early researchStudy completedNCT04977674
What this trial is testing

Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine

Who this might be right for
Depressive Disorder, Treatment-Resistant
King's College London 27
Testing effectiveness (Phase 2)Study completedNCT01998958
What this trial is testing

Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

Who this might be right for
Treatment Resistant Depressive Disorder
Janssen Research & Development, LLC 108
Testing effectiveness (Phase 2)Ended earlyNCT01921543
What this trial is testing

Deep Brain Stimulation in Treatment Refractory Depression

Who this might be right for
Major Depressive Disorder
Universitaire Ziekenhuizen KU Leuven 7
Not applicableStudy completedNCT02752178
What this trial is testing

Peripheral Immunomarker Validation in Treatment-resistant Depression

Who this might be right for
Depressive Disorder, Major
University of Cambridge 393
Not applicableStudy completedNCT07097025
What this trial is testing

2-Year Study of Vagus Nerve Stimulation for Higher-Grade Treatment-Resistant Depression: Clinical Outcomes and Policy Recommendation

Who this might be right for
Treatment Resistant Depression (TRD)Depression - Major Depressive DisorderBipolar Depression
Dr.Yoav Domany 19
Not applicableLooking for participantsNCT07108257
What this trial is testing

Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression

Who this might be right for
Treatment-Resistant DepressionBipolar Depression
Sunnybrook Health Sciences Centre 10
Not applicableNot Yet RecruitingNCT07783906
What this trial is testing

Precision Closed-loop Brain-Computer Interface Neuromodulation for Treatment-Resistant Depression

Who this might be right for
Treatment-Resistant Major Depressive DisorderMajor Depressive Disorder
Shanghai Mental Health Center 70
Testing effectiveness (Phase 2)Study completedNCT01793610
What this trial is testing

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

Who this might be right for
Posttraumatic Stress Disorder
Resilient Pharmaceuticals 29
Testing effectiveness (Phase 2)Study completedNCT01204918
What this trial is testing

Efficacy and Tolerability of Riluzole in Treatment Resistant Depression

Who this might be right for
Depression
Yale University 104
Early research (Phase 1)Not Yet RecruitingNCT07307768
What this trial is testing

Ketamine Biomarker Validation

Who this might be right for
Treatment Resistant Depression (TRD)
Soterix Medical 20
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