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Results for “Dopamine Receptor Occupancy”

24 trials

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Showing 20 of 24 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02815917
What this trial is testing

Evaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CT

Who this might be right for
D3 Dopamine ReceptorCocaine-dependentHealthy Volunteer
University of Pennsylvania 30
Post-approval studies (Phase 4)Study completedNCT00302367
What this trial is testing

An Open Label Phase I/II Study of Dopamine Transporter Receptor Occupancy With OROS and Immediate Release Methylphenidate as Measured With C-11 Altropane in Human Subjects

Who this might be right for
Healthy Volunteers
Massachusetts General Hospital 20
Post-approval studies (Phase 4)Not Yet RecruitingNCT05060549
What this trial is testing

Dopamine D3 Receptor Occupancy in Bipolar Depression

Who this might be right for
Bipolar Depression
New York State Psychiatric Institute 8
Early research (Phase 1)Study completedNCT00796432
What this trial is testing

Dopamine Type 2 (D2) Receptor Occupancy Following a Single Oral Dose of OROS Paliperidone

Who this might be right for
Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 4
Early research (Phase 1)Study completedNCT00814957
What this trial is testing

An Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET Ligand

Who this might be right for
Substance Dependence
GlaxoSmithKline 12
Early research (Phase 1)Study completedNCT06300580
What this trial is testing

Study of Oral ABBV-932 Capsules to Evaluate Dopamine D2 and D3 Receptor Occupancy in Brain in Adult Healthy Volunteers

Who this might be right for
Healthy Volunteers
AbbVie 11
Testing effectiveness (Phase 2)Study completedNCT00593138
What this trial is testing

Study of Dopamine Transporter Receptor Occupancy With Long-acting Dex-methylphenidate

Who this might be right for
Drug Binding to DAT Receptors
Massachusetts General Hospital 23
Not applicableStudy completedNCT01562808
What this trial is testing

Change in Brain Metabolism and Cognitive Function by Aripiprazole

Who this might be right for
AntipsychoticsCognitionBrain Metabolism+1 more
Seoul National University Hospital 15
Early research (Phase 1)Study completedNCT00468806
What this trial is testing

Study of Safety, Blood Levels and Brain Receptor Occupancy of GSK598809 Using PET Imaging in Health Males.

Who this might be right for
Healthy Subjects
GlaxoSmithKline 25
Large-scale testing (Phase 3)Study completedNCT00301639
What this trial is testing

A PET Study Examining Pharmacokinetics and Dopamine Transporter Receptor Occupancy Of Two Long-Acting Formulations of Methylphenidate in Adults

Who this might be right for
Healthy Volunteers
Massachusetts General Hospital 40
Post-approval studies (Phase 4)Ended earlyNCT00934635
What this trial is testing

A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls

Who this might be right for
Schizophrenia
Janssen-Cilag G.m.b.H 2
Not applicableUnknownNCT00825045
What this trial is testing

Dopamine D2 and D3 Receptor Occupancy and Clinical Response in Older Patients With Schizophrenia

Who this might be right for
SchizophreniaSchizoaffective DisorderSchizophreniform Disorder
Centre for Addiction and Mental Health 14
Not applicableStudy completedNCT01660880
What this trial is testing

Validation of Receptor Occupancy Simulation

Who this might be right for
Dopamine Receptor OccupancyMedication SatisfactionProlactin Level+1 more
Seoul National University Hospital 7
Not applicableUnknownNCT02880995
What this trial is testing

[18 Fluorine(F)]DOPA Determinants and Predictors of Treatment Response in Psychosis

Who this might be right for
Schizophrenia
Seoul National University Hospital 62
Testing effectiveness (Phase 2)Study completedNCT01699828
What this trial is testing

Exploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PET

Who this might be right for
Smoking CessationTobacco Use Cessation
Centre for Addiction and Mental Health 6
Early research (Phase 1)Study completedNCT02333487
What this trial is testing

Positron Emission Tomography (PET) Study Investigating Dopamine and Serotonin Receptor Occupancy After Multiple Oral Dosing of Lu AF35700

Who this might be right for
Schizophrenia
H. Lundbeck A/S 22
Large-scale testing (Phase 3)Study completedNCT00302393
What this trial is testing

Study Examining Repeat Dosing of OROS® Methylphenidate (CONCERTA®) and Immediate Release Methylphenidate in Healthy Adults

Who this might be right for
Healthy
Massachusetts General Hospital 20
Not applicableUnknownNCT02884518
What this trial is testing

Predicting Antipsychotic Discontinuation in Psychosis

Who this might be right for
Schizophrenia
Seoul National University Hospital 35
Post-approval studies (Phase 4)Study completedNCT00846339
What this trial is testing

PET Imaging Study on Occupancy of Dopamine D2 Receptors and Genotypes After Bupropion Administration

Who this might be right for
Smoking
Seoul National University Hospital 12
Not applicableStudy completedNCT00818298
What this trial is testing

24-Hour Time Course of Striatal Dopamine D2 Receptor Occupancy of Ziprasidone: A PET Study

Who this might be right for
SchizophreniaSchizoaffective Disorder
Centre for Addiction and Mental Health 12
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