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Results for “Dopamine Receptor Occupancy”

25 trials

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Showing 20 of 25 results

Large-scale testing (Phase 3)Study completedNCT00301639
What this trial is testing

A PET Study Examining Pharmacokinetics and Dopamine Transporter Receptor Occupancy Of Two Long-Acting Formulations of Methylphenidate in Adults

Who this might be right for
Healthy Volunteers
Massachusetts General Hospital 40
Not applicableUnknownNCT00825045
What this trial is testing

Dopamine D2 and D3 Receptor Occupancy and Clinical Response in Older Patients With Schizophrenia

Who this might be right for
SchizophreniaSchizoaffective DisorderSchizophreniform Disorder
Centre for Addiction and Mental Health 14
Early research (Phase 1)Study completedNCT00832221
What this trial is testing

Positron Emission Tomography (PET) Study With [11C]Raclopride to Determine Central D2 Dopamine Occupancy of SEROQUEL

Who this might be right for
Depression
AstraZeneca 10
Testing effectiveness (Phase 2)Study completedNCT01699828
What this trial is testing

Exploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PET

Who this might be right for
Smoking CessationTobacco Use Cessation
Centre for Addiction and Mental Health 6
Large-scale testing (Phase 3)Study completedNCT00302393
What this trial is testing

Study Examining Repeat Dosing of OROS® Methylphenidate (CONCERTA®) and Immediate Release Methylphenidate in Healthy Adults

Who this might be right for
Healthy
Massachusetts General Hospital 20
Not applicableUnknownNCT02884518
What this trial is testing

Predicting Antipsychotic Discontinuation in Psychosis

Who this might be right for
Schizophrenia
Seoul National University Hospital 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT02815917
What this trial is testing

Evaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CT

Who this might be right for
D3 Dopamine ReceptorCocaine-dependentHealthy Volunteer
University of Pennsylvania 30
Post-approval studies (Phase 4)Study completedNCT00846339
What this trial is testing

PET Imaging Study on Occupancy of Dopamine D2 Receptors and Genotypes After Bupropion Administration

Who this might be right for
Smoking
Seoul National University Hospital 12
Not applicableStudy completedNCT01660880
What this trial is testing

Validation of Receptor Occupancy Simulation

Who this might be right for
Dopamine Receptor OccupancyMedication SatisfactionProlactin Level+1 more
Seoul National University Hospital 7
Early research (Phase 1)Study completedNCT00814957
What this trial is testing

An Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET Ligand

Who this might be right for
Substance Dependence
GlaxoSmithKline 12
Post-approval studies (Phase 4)Ended earlyNCT00934635
What this trial is testing

A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls

Who this might be right for
Schizophrenia
Janssen-Cilag G.m.b.H 2
Not applicableStudy completedNCT01562808
What this trial is testing

Change in Brain Metabolism and Cognitive Function by Aripiprazole

Who this might be right for
AntipsychoticsCognitionBrain Metabolism+1 more
Seoul National University Hospital 15
Not applicableStudy completedNCT00818298
What this trial is testing

24-Hour Time Course of Striatal Dopamine D2 Receptor Occupancy of Ziprasidone: A PET Study

Who this might be right for
SchizophreniaSchizoaffective Disorder
Centre for Addiction and Mental Health 12
Testing effectiveness (Phase 2)Study completedNCT00593138
What this trial is testing

Study of Dopamine Transporter Receptor Occupancy With Long-acting Dex-methylphenidate

Who this might be right for
Drug Binding to DAT Receptors
Massachusetts General Hospital 23
Early research (Phase 1)Study completedNCT04588129
What this trial is testing

Receptor Occupancy of LB-102 Using Positron Emission Tomography (PET) in Healthy Volunteers

Who this might be right for
Schizophrenia
LB Pharmaceuticals Inc. 16
Not applicableUnknownNCT02880995
What this trial is testing

[18 Fluorine(F)]DOPA Determinants and Predictors of Treatment Response in Psychosis

Who this might be right for
Schizophrenia
Seoul National University Hospital 62
Early research (Phase 1)Study completedNCT02333487
What this trial is testing

Positron Emission Tomography (PET) Study Investigating Dopamine and Serotonin Receptor Occupancy After Multiple Oral Dosing of Lu AF35700

Who this might be right for
Schizophrenia
H. Lundbeck A/S 22
Early research (Phase 1)Study completedNCT02093169
What this trial is testing

D2 Dopamine Receptor Occupancy After Oral Dosing of Lu AF35700 in Healthy Men Using [11C]-PHNO as Tracer Compound

Who this might be right for
Healthy Men
H. Lundbeck A/S 12
Early research (Phase 1)Study completedNCT00468806
What this trial is testing

Study of Safety, Blood Levels and Brain Receptor Occupancy of GSK598809 Using PET Imaging in Health Males.

Who this might be right for
Healthy Subjects
GlaxoSmithKline 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07626034
What this trial is testing

A Positron Emission Tomography (PET) Study to Evaluate Dopamine D2 and D3 Receptor Occupancy by SIPI6398

Who this might be right for
Schizophrenia Disorder
Shanghai Zhongze Therapeutics Co., Ltd. 9
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