Not applicableUnknownNCT04469140What this trial is testingNon Exudative AMD Imaged With SS-OCT- ExtensionWho this might be right forDry Macular Degeneration Boston Image Reading Center 450
Large-scale testing (Phase 3)Study completedNCT04435366What this trial is testingSafety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)Who this might be right forGeographic AtrophyMacular Degeneration IVERIC bio, Inc. 448
Post-approval studies (Phase 4)Study completedNCT01775124What this trial is testingEfficacy and Safety of Ranibizumab 0.5 mg Administered as Two Alternative Dosing Regimens in Chinese Patients With nAMD (Age Related Macular Degeneration)Who this might be right forNeovascular Age-related Macular Degeneration Novartis Pharmaceuticals 332
Not applicableStudy completedNCT03333954What this trial is testingFeasibility Study of Compensation for Blindness With the PRIMA System in Patients With Dry Age Related Macular DegenerationWho this might be right forDry Age-related Macular Degeneration Science Corporation 5
Testing effectiveness (Phase 2)Study completedNCT03815825What this trial is testingGOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)Who this might be right forMacular DegenerationGeographic Atrophy Ionis Pharmaceuticals, Inc. 332
Large-scale testing (Phase 3)Study completedNCT03525613What this trial is testingCompare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular DegenerationWho this might be right forGeographic Atrophy Apellis Pharmaceuticals, Inc. 637
Not applicableStudy completedNCT01890187What this trial is testingRepeatability and Reproducibility of Cirrus HD-OCT Measurements of Illumination Areas Under the Retinal Pigment EpitheliumWho this might be right forAdvanced Dry AMD With Geographic Atrophy Carl Zeiss Meditec, Inc. 85
Testing effectiveness (Phase 2)Study completedNCT02684578What this trial is testingMetformin for the Minimization of Geographic Atrophy Progression in Patients With AMDWho this might be right forAge-Related Macular DegenerationMacular Degeneration, Age-RelatedDry Macular Degeneration+1 more University of California, San Francisco 66
Testing effectiveness (Phase 2)Study completedNCT03927690What this trial is testingMultiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular EdemaWho this might be right forDiabetic Macular Edema Novartis Pharmaceuticals 91
Not applicableStudy completedNCT02332343What this trial is testingSparing of the Fovea in Geographic Atrophy ProgressionWho this might be right forAtrophyGeographic AtrophyAge-related Macular Degeneration+1 more University Hospital, Bonn 26
Testing effectiveness (Phase 2)Ended earlyNCT04437368What this trial is testingEXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005Who this might be right forDry Age-related Macular Degeneration Gyroscope Therapeutics Limited 98
Testing effectiveness (Phase 2)Study completedNCT02288559What this trial is testingLampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic AtrophyWho this might be right forGeographic Atrophy Genentech, Inc. 96
Post-approval studies (Phase 4)Study completedNCT04679935What this trial is testingEfficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular DegenerationWho this might be right forAge-related Macular Degeneration Novartis Pharmaceuticals 52
Not applicableLooking for participantsNCT06375239What this trial is testingObservational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal DegenerationWho this might be right forRetinitis PigmentosaChoroideremiaStargardt Macular Dystrophy+4 more Ray Therapeutics, Inc. 120
Testing effectiveness (Phase 2)Study completedNCT00658619What this trial is testingSafety and Efficacy of Brimonidine Intravitreal Implant in Patients With Geographic Atrophy Due to Age-related Macular Degeneration (AMD)Who this might be right forMacular Degeneration Allergan 119
Large-scale testing (Phase 3)Study completedNCT04264819What this trial is testingStudy of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular DegenerationWho this might be right forNeovascular Age-Related Macular Degeneration Novartis Pharmaceuticals 295
Testing effectiveness (Phase 2)WithdrawnNCT04358471What this trial is testingIntravitreal AAVCAGsCD59 for Advanced Dry Age-related Macular Degeneration (AMD) With Geographic Atrophy (GA)Who this might be right forDry Age-related Macular DegenerationGeographic AtrophyGene Therapy+1 more Hemera Biosciences
Not applicableStudy completedNCT07428798What this trial is testingSubtenon PRP Injection for Geographic Atrophy in Dry Age-Related Macular DegenerationWho this might be right forGeographic AtrophyDry Age Related Macular Degeneration Marmara University Pendik Training and Research Hospital 14
Testing effectiveness (Phase 2)WithdrawnNCT03446144What this trial is testingSafety and Efficacy of IONIS-FB-Lrx in up to 120 Patients 55 and Older With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)Who this might be right forGeographic AtrophyAge Related Macular Degeneration Ionis Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Study completedNCT02659098What this trial is testingEvaluate the Safety and Clinical Response of Subretinal Administration of CNTO 2476 in Participants With Geographic AtrophyWho this might be right forVisual AcuityGeographic AtrophyMacular Degeneration Janssen Research & Development, LLC 21