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Results for “Hereditary Optic Atrophies”

140 trials

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Showing 20 of 140 results

Not applicableNo Longer AvailableNCT04381091
What this trial is testing

Expanded Access Program for Idebenone in Patients With Leber's Hereditary Optic Neuropathy Who Completed the LEROS Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Not applicableLooking for participantsNCT06306690
What this trial is testing

Biomarkers in Retinitis Pigmentosa

Who this might be right for
Retinitis Pigmentosa
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 35
Early research (Phase 1)Study completedNCT02161380
What this trial is testing

Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Byron Lam 28
Not applicableStudy completedNCT03295071
What this trial is testing

REALITY LHON Registry

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 44
Early research (Phase 1)Study completedNCT04246866
What this trial is testing

First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry Age Related Macular Degeneration

Who this might be right for
Dry Age-related Macular DegenerationGeographic AtrophyMacular Degeneration+2 more
Gemini Therapeutics, Inc. 12
Large-scale testing (Phase 3)Ended earlyNCT02878694
What this trial is testing

Treatment of Ptosis to Muscular Dystrophy Oculopharyngeal by Myoblast Autologous Graft

Who this might be right for
Muscular Dystrophy, OculopharyngealPtosis
University Hospital, Caen 1
Testing effectiveness (Phase 2)Looking for participantsNCT07174687
What this trial is testing

SGLT2 Inhibitors in Geographic Atrophy

Who this might be right for
Retinal DegenerationRetinal DiseasesEye Diseases+2 more
Washington University School of Medicine 70
Early research (Phase 1)Study completedNCT01003691
What this trial is testing

Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic Atrophy

Who this might be right for
Age-Related MaculopathyAge-Related MaculopathiesEye Diseases+2 more
Pfizer 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03717909
What this trial is testing

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Who this might be right for
Wolfram Syndrome
University of Birmingham 63
Not applicableStudy completedNCT05555784
What this trial is testing

Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Argo Sante 12
Not applicableUnknownNCT01522638
What this trial is testing

Advanced Characterization of Autosomal Dominant Optic Atrophy

Who this might be right for
Optic Atrophy, Autosomal Dominant
Glostrup University Hospital, Copenhagen 50
Not applicableStudy completedNCT02699190
What this trial is testing

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

Who this might be right for
LeukodystrophyWhite Matter Disease4H Syndrome+61 more
Children's Hospital of Philadelphia 236
Not applicableStudy completedNCT04723160
What this trial is testing

Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph

Who this might be right for
Diabetic RetinopathyRetinal Vein OcclusionRetinal Artery Occlusion+10 more
Visionary Intelligence Ltd. 748
Testing effectiveness (Phase 2)Study completedNCT00747487
What this trial is testing

Study to Assess Efficacy,Safety and Tolerability of Idebenone in the Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 85
Not applicableWithdrawnNCT01302327
What this trial is testing

GLP Analogs for Diabetes in Wolfram Syndrome Patients

Who this might be right for
Diabetes Mellitus Associated With Genetic SyndromeWolfram Syndrome
Hadassah Medical Organization
Testing effectiveness (Phase 2)Study completedNCT02064569
What this trial is testing

Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 19
Not applicableLooking for participantsNCT00874783
What this trial is testing

Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases

Who this might be right for
Neurodegenerative Disorders
Hadassah Medical Organization 120
Not applicableLooking for participantsNCT03475173
What this trial is testing

New Non-invasive Modalities for Assessing Retinal Structure and Function

Who this might be right for
Ischemic Optic NeuropathyBranch Retinal Artery OcclusionHemianopia+2 more
Randy Kardon 500
Not applicableStudy completedNCT02574039
What this trial is testing

Oat Phenolics Bioavailability

Who this might be right for
Healthy
University of Reading 7
Not applicableStudy completedNCT01303562
What this trial is testing

Clinical Assessment of Barley and Oat Phytochemicals

Who this might be right for
Healthy
Tufts University 13
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