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Results for “Hereditary Optic Atrophies”

143 trials

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Showing 20 of 143 results

Large-scale testing (Phase 3)Study completedNCT03772665
What this trial is testing

Safety and Efficacy of Emixustat in Stargardt Disease

Who this might be right for
Stargardt Disease
Kubota Vision Inc. 194
Testing effectiveness (Phase 2)Ended earlyNCT05820152
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 11
Not applicableLooking for participantsNCT02194816
What this trial is testing

Modifiable Variables in Parkinsonism (MVP)

Who this might be right for
Parkinson's DiseaseParkinsonismMSA - Multiple System Atrophy+6 more
Bastyr University 2,000
Testing effectiveness (Phase 2)UnknownNCT04940572
What this trial is testing

Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome

Who this might be right for
Wolfram Syndrome
Centre d'Etude des Cellules Souches 23
Not applicableStudy completedNCT02796274
What this trial is testing

Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 219
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableUnknownNCT01522638
What this trial is testing

Advanced Characterization of Autosomal Dominant Optic Atrophy

Who this might be right for
Optic Atrophy, Autosomal Dominant
Glostrup University Hospital, Copenhagen 50
Early research (Phase 1)Study completedNCT00001735
What this trial is testing

Gene Therapy for Gyrate Atrophy

Who this might be right for
Gyrate Atrophy
National Eye Institute (NEI) 5
Testing effectiveness (Phase 2)Looking for participantsNCT07303296
What this trial is testing

Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients

Who this might be right for
Leber Hereditary Optic Disease
GenSight Biologics 14
Early research (Phase 1)Study completedNCT04246866
What this trial is testing

First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry Age Related Macular Degeneration

Who this might be right for
Dry Age-related Macular DegenerationGeographic AtrophyMacular Degeneration+2 more
Gemini Therapeutics, Inc. 12
Testing effectiveness (Phase 2)Ended earlyNCT01389817
What this trial is testing

Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Medical College of Wisconsin 4
Testing effectiveness (Phase 2)Looking for participantsNCT07174687
What this trial is testing

SGLT2 Inhibitors in Geographic Atrophy

Who this might be right for
Retinal DegenerationRetinal DiseasesEye Diseases+2 more
Washington University School of Medicine 70
Large-scale testing (Phase 3)Study completedNCT04636853
What this trial is testing

CB-PRP in Retinitis Pigmentosa and Dry Age-related Macular Degeneration

Who this might be right for
Retinitis PigmentosaDry Age-related Macular Degeneration
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20
Not applicableStudy completedNCT00001166
What this trial is testing

Gyrate Atrophy of the Choroid and Retina

Who this might be right for
Gyrate Atrophy
National Eye Institute (NEI) 65
Testing effectiveness (Phase 2)Ended earlyNCT04566445
What this trial is testing

HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

Who this might be right for
Dry Age-related Macular Degeneration
Gyroscope Therapeutics Limited 255
Not applicableStudy completedNCT01712555
What this trial is testing

Autologous Fat Grafting With PRP (Platelet Rich Plasma) to Anophthalmic Sockets

Who this might be right for
Orbital Atrophy
Fox, Donald Munro, M.D., P.C. 5
Not applicableLooking for participantsNCT02994719
What this trial is testing

Gait Analysis in Neurological Disease

Who this might be right for
Parkinson's DiseaseParkinsonian DisordersAtypical Parkinson Disease+5 more
Beth Israel Deaconess Medical Center 120
Not applicableWithdrawnNCT02699216
What this trial is testing

BioCurrent Electrical Stimulation for the Treatment of Dry ARMD

Who this might be right for
Dry Macular Degeneration
DuBois Vision Clinic
Large-scale testing (Phase 3)Looking for participantsNCT06891443
What this trial is testing

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 32
Testing effectiveness (Phase 2)Active Not RecruitingNCT05293626
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 12
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