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Results for “High LDL-C”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT03397121
What this trial is testing

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial HypercholesterolemiaElevated Cholesterol
The Medicines Company 482
Early research (Phase 1)Study completedNCT05912296
What this trial is testing

A Single and Multiple Ascending Doses Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RBD7022

Who this might be right for
Hyperlipemia
Suzhou Ribo Life Science Co. Ltd. 80
Large-scale testing (Phase 3)Study completedNCT02392559
What this trial is testing

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Amgen 158
Post-approval studies (Phase 4)Study completedNCT07255820
What this trial is testing

Dual vs Triple Lipid-Lowering Therapy in Type 2 Diabetes Mellitus Patients With Elevated LDL Cholesterol

Who this might be right for
Type 2 Diabetes MellitusHypercholesterolemia / Elevated LDL Cholesterol
Bahria University 126
Large-scale testing (Phase 3)Looking for participantsNCT06597006
What this trial is testing

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 9
Not applicableStudy completedNCT05218005
What this trial is testing

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein BFamilial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation+5 more
University of British Columbia 140
Not applicableNot Yet RecruitingNCT05587621
What this trial is testing

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)

Who this might be right for
ST Elevation Myocardial InfarctionNon-ST Elevation Myocardial InfarctionLDL-cholesterol
Jena University Hospital 300
Large-scale testing (Phase 3)Not Yet RecruitingNCT07242599
What this trial is testing

Ongericimab Injection Reducing Recurrence of Ischemic Stroke

Who this might be right for
Ischemic Cerebral Infarction
Beijing Tiantan Hospital 4,810
Testing effectiveness (Phase 2)Study completedNCT04666298
What this trial is testing

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 312
Large-scale testing (Phase 3)Ended earlyNCT02227784
What this trial is testing

Evacetrapib (LY2484595) in Participants With High Cholesterol

Who this might be right for
Hyperlipidemia
Eli Lilly and Company 366
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Early research (Phase 1)Study completedNCT00055042
What this trial is testing

Laser and Antioxidant Treatment of Diabetic Macular Edema

Who this might be right for
Macular EdemaDiabetes Mellitus
National Eye Institute (NEI) 40
Large-scale testing (Phase 3)Study completedNCT01562080
What this trial is testing

Combined Effects of Bioactive Compounds in Lipid Profile

Who this might be right for
HyperlipidemiaLow-density-lipoprotein-typeElevated Triglycerides
Rottapharm Spain 118
Testing effectiveness (Phase 2)Study completedNCT01439880
What this trial is testing

Open Label Study of Long Term Evaluation Against LDL-C Trial

Who this might be right for
Hypercholesterolemia
Amgen 1,324
Early research (Phase 1)Study completedNCT05384262
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

Who this might be right for
Dyslipidemia
AstraZeneca 183
Not applicableStudy completedNCT00240344
What this trial is testing

Study in High Risk Patients Switched From Higher Doses of Other Statins to Crestor on the Percentage of Patients Reaching the New LDL-C Target Goal

Who this might be right for
Hypercholesterolemia
AstraZeneca 2,650
Early research (Phase 1)Study completedNCT00027287
What this trial is testing

Laser and Medical Treatment of Diabetic Macular Edema

Who this might be right for
Diabetes MellitusMacular Edema
National Eye Institute (NEI) 60
Large-scale testing (Phase 3)Study completedNCT04929249
What this trial is testing

Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE)

Who this might be right for
Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals 450
Large-scale testing (Phase 3)Study completedNCT01953328
What this trial is testing

Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk

Who this might be right for
Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events
Amgen 409
Large-scale testing (Phase 3)Study completedNCT01763528
What this trial is testing

High Protein Weight Loss Diet, High Sensitivity C-Reactive Protein and Cardiovascular Risks Among Obese Women

Who this might be right for
Body Mass Index Quantitative Trait Locus 8 DisorderTangier Disease
Isfahan University of Medical Sciences 63
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