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Results for “IPSS High Risk”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Ended earlyNCT02158936
What this trial is testing

Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Thrombocytopaenia
Novartis Pharmaceuticals 356
Testing effectiveness (Phase 2)WithdrawnNCT01324960
What this trial is testing

Azacitidine With or Without Ceplene/Interleukin-2 in Patients With Higher Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Groupe Francophone des Myelodysplasies
Testing effectiveness (Phase 2)Looking for participantsNCT06612944
What this trial is testing

Prophylactic Intervention for Relapse Prevention Post-Allogeneic Transplantation in Very High-Risk MDS Patients Based on IPSS-M Stratification

Who this might be right for
Myelodysplastic Syndromes, Adult
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 40
Early research (Phase 1)Ended earlyNCT00963495
What this trial is testing

Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaChronic Lymphocytic Leukemia+4 more
University Health Network, Toronto 11
Testing effectiveness (Phase 2)Ended earlyNCT00708721
What this trial is testing

Low-dose Oral Clofarabine for the Treatment of IPSS INT-1, INT-2 or HIGH Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Who this might be right for
CancerChronic Myelomonocytic Leukemia
University of Utah 11
Large-scale testing (Phase 3)UnknownNCT05175508
What this trial is testing

Aza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS

Who this might be right for
AMLMDSOld Age; Debility+1 more
The First Affiliated Hospital of Soochow University 180
Testing effectiveness (Phase 2)Ended earlyNCT02706899
What this trial is testing

Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS

Who this might be right for
Myelodysplastic Syndrome
Seagen Inc. 19
Testing effectiveness (Phase 2)Ended earlyNCT04878432
What this trial is testing

STIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDS

Who this might be right for
Myelodysplastic Syndrome (MDS)
Novartis Pharmaceuticals 39
Large-scale testing (Phase 3)Ended earlyNCT04266301
What this trial is testing

Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2)

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, Chronic
Novartis Pharmaceuticals 530
Testing effectiveness (Phase 2)Ended earlyNCT03151304
What this trial is testing

A Safety and Efficacy Study of Pracinostat and Azacitidine in Patients With High Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Helsinn Healthcare SA 64
Testing effectiveness (Phase 2)Study completedNCT00744536
What this trial is testing

Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDS

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicAngiogenesis
Sunnybrook Health Sciences Centre 20
Testing effectiveness (Phase 2)Ended earlyNCT00867308
What this trial is testing

Trial of High Dose Lenalidomide in Patients With MDS and AML With Trilineage Dysplasia

Who this might be right for
Myelodysplastic Syndrome
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 32
Testing effectiveness (Phase 2)WithdrawnNCT00867061
What this trial is testing

Efficacy and Safety of 5-day Dosing of ON 01910.Na in Intermediate-1,-2, or High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Myelodysplastic Syndrome
Traws Pharma, Inc.
Not applicableNot Yet RecruitingNCT07194187
What this trial is testing

High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction

Who this might be right for
Bladder Outlet ObstructionBPH
Icahn School of Medicine at Mount Sinai 17
Testing effectiveness (Phase 2)Study completedNCT02197676
What this trial is testing

A Phase II Trial of SGI-110 in Patients With IPSS High and Int 2 Myelodysplastic Syndrome, Acute Myeloid Leukemia With 20-30% Marrow Blasts or Chronic Myelomonocytic Leukemia Type 2 Not Responding to Azacitidine or Decitabine After at Least 6 Courses or Relapsing After a Response

Who this might be right for
MDS
Groupe Francophone des Myelodysplasies 56
Not applicableUnknownNCT06279338
What this trial is testing

A Novel Conditioning Regimen for Myelodysplastic Syndrome With Moderate High IPSS-M Score

Who this might be right for
Myelodysplastic Syndromes
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 40
Not applicableStudy completedNCT05218902
What this trial is testing

Azacitidine in Participants With International Prognostic Scoring System (IPSS) Intermediate-2 and High-risk Myelodysplastic Syndromes (MDS), or Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML)

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute
Bristol-Myers Squibb 290
Large-scale testing (Phase 3)Active Not RecruitingNCT05883956
What this trial is testing

A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myeloid, AcuteLeukemia, Myelomonocytic, Chronic+1 more
Otsuka Australia Pharmaceutical Pty Ltd 13
Testing effectiveness (Phase 2)Study completedNCT04806906
What this trial is testing

Pilot Study of CC 486 (Oral Azacitidine) Plus BSC as Maintenance After sc Azacitidine in Elderly HR-IPSS-R MDS Patients

Who this might be right for
MDSCMML
University of Florence 11
Testing effectiveness (Phase 2)UnknownNCT03094637
What this trial is testing

Azacitidine and Pembrolizumab in Treating Patients With Myelodysplastic Syndrome

Who this might be right for
High Risk Myelodysplastic SyndromeIPSS Risk Category Intermediate-1Myelodysplastic Syndrome
M.D. Anderson Cancer Center 40
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