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Results for “Locally Advanced Head and Neck HPV Negative Squamous Cell Cancers”

18 trials

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Showing 18 of 18 results

Testing effectiveness (Phase 2)Study completedNCT03944915
What this trial is testing

De-Escalation Therapy for Human Papillomavirus Negative Disease

Who this might be right for
Human Papilloma VirusSquamous Cell CarcinomaSquamous Cell Carcinoma of the Head and Neck+2 more
University of Chicago 35
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Testing effectiveness (Phase 2)Active Not RecruitingNCT05366166
What this trial is testing

Pembrolizumab Plus Olaparib in LA-HNSCC

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
UNC Lineberger Comprehensive Cancer Center 45
Testing effectiveness (Phase 2)Ended earlyNCT01732640
What this trial is testing

A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC.

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 9
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT02207439
What this trial is testing

Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Abramson Cancer Center at Penn Medicine 18
Not applicableActive Not RecruitingNCT05459415
What this trial is testing

Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC

Who this might be right for
Squamous Cell Carcinoma of Head and NeckNeoadjuvant TherapyResection Margin
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 54
Testing effectiveness (Phase 2)Looking for participantsNCT07195734
What this trial is testing

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Recurrent Head and Neck Squamous Cell Carcinoma+15 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)WithdrawnNCT05608369
What this trial is testing

Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC

Who this might be right for
HPV-Related Squamous Cell CarcinomaSquamous Cell Carcinoma of the Oral CavitySquamous Cell Carcinoma of the Larynx+2 more
Case Comprehensive Cancer Center
Not applicableUnknownNCT02336711
What this trial is testing

Molecular Imaging-based Dose Escalation in HPV Negative Patients With Locally Advanced SCC of the Oropharynx

Who this might be right for
Head and Neck Cancer
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 10
Early research (Phase 1)Looking for participantsNCT05172245
What this trial is testing

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Carcinoma of Unknown Primary+24 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT03795610
What this trial is testing

IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell CarcinomaHead and Neck CancerHead and Neck Carcinoma+5 more
Assuntina G. Sacco, MD 16
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06199271
What this trial is testing

Neoadjuvant Adebrelimab Plus Dalpiciclib in Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Zhongzheng Xiang 30
Early research (Phase 1)Looking for participantsNCT06005324
What this trial is testing

Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer

Who this might be right for
HPV-Negative Squamous Cell Carcinoma
University of Chicago 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Large-scale testing (Phase 3)UnknownNCT01880359
What this trial is testing

AF CRT +/- Nimorazole in HNSCC

Who this might be right for
Locally Advanced Head and Neck HPV Negative Squamous Cell Cancers
European Organisation for Research and Treatment of Cancer - EORTC 640
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07552558
What this trial is testing

Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

Who this might be right for
Head and Neck Squamous Cell CarcinomaHPV-Negative Squamous Cell Carcinoma
Washington University School of Medicine 45
Not applicableWithdrawnNCT04140513
What this trial is testing

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Oropharyngeal Squamous Cell Carcinoma+5 more
Ohio State University Comprehensive Cancer Center
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