Early research (Phase 1)Study completedNCT06498284What this trial is testingEvaluate HM-002-1005 in Subjects With Type 2 Diabetes MellitusWho this might be right forDiabetes Mellitus, Type II Hua Medicine Limited 40
Not applicableUnknownNCT04091854What this trial is testingThe Progress of Diabetes Mellitus After HMS5552 Treatment in Type 2 Diabetes MellitusWho this might be right forType2 Diabetes Mellitus Majianhua 24
Early research (Phase 1)Study completedNCT02077452What this trial is testingSafety, Tolerability, Pharmacokinetics and Pharmacodynamics of HMS5552 in Patients With Type 2 DiabetesWho this might be right forType 2 Diabetes Mellitus Hua Medicine Limited 53
Testing effectiveness (Phase 2)Study completedNCT02405260What this trial is testingAdd Glucokinase Activator to Target A1cWho this might be right forDiabetes Mellitus, Type 2 vTv Therapeutics 190
Not applicableLooking for participantsNCT06147414What this trial is testingDevelopment of Non-Invasive Prenatal Diagnosis for Single Gene DisordersWho this might be right forInvasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, IncludingSickle Cell DiseaseCystic Fibrosis+12 more Assistance Publique - Hôpitaux de Paris 550
Post-approval studies (Phase 4)WithdrawnNCT02198209What this trial is testingLiraglutide Actions on the Liver: Effects on Glucose PhosphorylationWho this might be right forType 2 Diabetes Cedars-Sinai Medical Center
Testing effectiveness (Phase 2)Study completedNCT04516759What this trial is testingAZD1656 in Diabetic Patients Hospitalised With Suspected or Confirmed COVID-19Who this might be right forCovid19 St George Street Capital 170
Early research (Phase 1)Study completedNCT03414892What this trial is testingMultiple Ascending Doses of Globalagliatin Hydrochloride in Type 2 Diabetes MellitusWho this might be right forHyperglycaemia (Diabetic)Type 2 Diabetes Mellitus Yabao Pharmaceutical Group 24
Not applicableNot Yet RecruitingNCT06671340What this trial is testingChronic Dorzagliatin on Insulin and Incretin Function in Intermediate Hyperglycemia and Type 2 DiabetesWho this might be right forDiabetes MellitusPrediabetes / Type 2 Diabetes Elaine Chow 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05098470What this trial is testingEffects of Modulators of Gluconeogenesis, Glycogenolysis and Glucokinase ActivityWho this might be right forType 2 Diabetes University of Alabama at Birmingham 100
Early research (Phase 1)Study completedNCT03973515What this trial is testingClinical Trial for the Investigational Drug (PB-201) in Subjects With Type 2 Diabetes MellitusWho this might be right forType2 Diabetes Mellitus PegBio Co., Ltd. 16
Testing effectiveness (Phase 2)Ended earlyNCT01029795What this trial is testingLY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes MellitusWho this might be right forDiabetes Mellitus, Type 2 Eli Lilly and Company 38
Early research (Phase 1)Study completedNCT01247363What this trial is testingLY2608204 in Patients With Type 2 DiabetesWho this might be right forDiabetes Mellitus, Type 2 Eli Lilly and Company 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06976658What this trial is testingGlucokinase Activator in Monogenic DiabetesWho this might be right forDiabetes MellitusMonogenic Diabetes Chinese University of Hong Kong 44
Early research (Phase 1)Study completedNCT02971202What this trial is testingContribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2)Who this might be right forType 1 Diabetes MellitusMaturity-Onset Diabetes of the Young, Type 2MODY2+1 more Vanderbilt University 33
Not applicableStudy completedNCT02556840What this trial is testingImpact on Birth Weight of Two Therapeutic Strategies (Insulin Therapy From the Beginning of Pregnancy vs. Insulin Therapy Initiated According to Fetal Growth Evaluated by Ultrasonography Measurements) in Pregnant Women With Monogenic DiabetesWho this might be right forMaturity-Onset Diabetes of the Young Assistance Publique - Hôpitaux de Paris 46
Very early researchLooking for participantsNCT06609356What this trial is testingCardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 DiabetesWho this might be right forType 1 Diabetes MellitusGlucokinase-Maturity Onset Diabetes of the Young (GCK-MODY)MODY2 Diabetes+1 more Vanderbilt University Medical Center 27
Early research (Phase 1)Temporarily pausedNCT01472809What this trial is testingA Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral ZYGK1 in Healthy VolunteersWho this might be right forDiabetes Zydus Lifesciences Limited 96
Not applicableUnknownNCT01960231What this trial is testingThe Effect of ß-cell Specific Glucokinase Mutation on Glucose Homeostasis and Insulin Secretion in a MODY-2 FamilyWho this might be right forMODY-2 Diabetes Sheba Medical Center 30
Early research (Phase 1)Study completedNCT02597400What this trial is testingDrug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DMWho this might be right forType 2 Diabetes Mellitus Hua Medicine Limited 12