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Results for “MSS, Microsatellite Stable Colon Cancer”

81 trials

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Showing 20 of 81 results

Testing effectiveness (Phase 2)Study completedNCT03800602
What this trial is testing

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaRefractory Colorectal Carcinoma+5 more
Emory University 29
Testing effectiveness (Phase 2)Study completedNCT02860546
What this trial is testing

A Study Evaluating TAS-102 Plus Nivolumab in Patients With MSS CRC

Who this might be right for
Refractory Metastatic Colorectal Cancer
Taiho Oncology, Inc. 18
Early research (Phase 1)UnknownNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07229872
What this trial is testing

A Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Fruquintinib in the Treatment of Immunodominant pMMR/MSS Metastatic Colorectal Cancer That Has Failed Second-line or Above Treatment

Who this might be right for
Colorectal Cancer
Harbin Medical University 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT05608044
What this trial is testing

Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Agenus Inc. 234
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Testing effectiveness (Phase 2)UnknownNCT04653480
What this trial is testing

Surufatinib, Toripalimab and Chemotherapy in Second-line MT and MSS CRC

Who this might be right for
Colorectal Cancer
Zhejiang University 61
Early research (Phase 1)Not Yet RecruitingNCT07363408
What this trial is testing

Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer

Who this might be right for
Advanced Microsatellite Stable Colorectal CarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaStage III Colorectal Cancer AJCC v8+1 more
City of Hope Medical Center 30
Testing effectiveness (Phase 2)Ended earlyNCT05572684
What this trial is testing

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more
NextCure, Inc. 97
Testing effectiveness (Phase 2)Active Not RecruitingNCT06699836
What this trial is testing

CLOVER - CCR5-targeting Leronlimab With Oral Chemotherapy and VEGF-inhibitor Enriched Regimen

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
CytoDyn, Inc. 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07359456
What this trial is testing

Testing Ivonescimab in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancers Without Liver Metastases

Who this might be right for
Metastatic Colorectal Cancer
UNICANCER 130
Early research (Phase 1)Looking for participantsNCT07540572
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

Who this might be right for
ER+, HER 2- Breast CancerNon-small Cell Lung Cancer (NSCLC)Castration-resistant Prostate Cancer (CRPC)+1 more
IDEAYA Biosciences 160
Testing effectiveness (Phase 2)Looking for participantsNCT05959356
What this trial is testing

Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Sun Yat-sen University 198
Early research (Phase 1)Active Not RecruitingNCT06544655
What this trial is testing

BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 213
Testing effectiveness (Phase 2)Ended earlyNCT03207867
What this trial is testing

NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

Who this might be right for
NSCLC, Non Small Cell Lung CancerRCC, Renal Cell CancerPancreatic Cancer+7 more
Novartis Pharmaceuticals 315
Testing effectiveness (Phase 2)UnknownNCT05160727
What this trial is testing

Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer

Who this might be right for
Mismatch Repair-proficientColorectal Cancer MetastaticMicrosatellite Stable
Zhejiang Cancer Hospital 44
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Testing effectiveness (Phase 2)Active Not RecruitingNCT06784947
What this trial is testing

Trial of Atezolizumab, Bevacizumab, and Tiragolumab in Patients With Microsatellite Stable, Metastatic Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal Cancer (CRC)Metastatic Colorectal Cancer (CRC)Colorectal Cancer Stage IV
University of Colorado, Denver 13
Early research (Phase 1)Study completedNCT04354246
What this trial is testing

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Who this might be right for
Advanced CancerOvarian CancerLung Cancer+6 more
Compugen Ltd 94
Large-scale testing (Phase 3)Not Yet RecruitingNCT07132008
What this trial is testing

Neoadjuvant CAPOX Plus Tislelizumab vs CAPOX in MSS High-Risk Locally Advanced Colon Cancer

Who this might be right for
Colonic NeoplasmsNeoadjuvant TherapyImmune Checkpoint Inhibitors
First Affiliated Hospital of Guangxi Medical University 94
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