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Results for “MSS, Microsatellite Stable Colon Cancer”

76 trials

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Showing 20 of 76 results

Early research (Phase 1)Looking for participantsNCT07321106
What this trial is testing

Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography Biosciences 80
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Testing effectiveness (Phase 2)UnknownNCT04724239
What this trial is testing

Sintilimab and Chidamide in Combination With or Without IBI305 in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
Advanced Microsatellite Stable Colorectal CancerMetastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 48
Testing effectiveness (Phase 2)Looking for participantsNCT06567782
What this trial is testing

Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer

Who this might be right for
Neoplasms, Colon
GlaxoSmithKline 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Very early researchLooking for participantsNCT07328087
What this trial is testing

COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColorectal Cancer Stage IIIColorectal Cancer Stage IV
Biogenea Pharmaceuticals Ltd. 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04068610
What this trial is testing

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
MedImmune LLC 61
Post-approval studies (Phase 4)UnknownNCT02887365
What this trial is testing

A Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon Cancer

Who this might be right for
MSI-L/MSSStage II Colon Cancer
National Taiwan University Hospital 300
Testing effectiveness (Phase 2)UnknownNCT04535024
What this trial is testing

The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Fudan University 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT06268015
What this trial is testing

Botensilimab and Balstilimab Optimization in Colorectal Cancer

Who this might be right for
Colorectal Cancer
Nicholas DeVito, MD 16
Testing effectiveness (Phase 2)WithdrawnNCT05178576
What this trial is testing

A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy

Who this might be right for
Colon Cancer
NSABP Foundation Inc
Testing effectiveness (Phase 2)Active Not RecruitingNCT05627635
What this trial is testing

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+4 more
City of Hope Medical Center 20
Testing effectiveness (Phase 2)Ended earlyNCT03791398
What this trial is testing

BrUOG 379 Phase Ib/II Trial ONC201 + Nivolumab in MSS mCRC

Who this might be right for
Metastatic Colorectal Cancer
Brown University 13
Testing effectiveness (Phase 2)Looking for participantsNCT05919264
What this trial is testing

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
CancerColorectal CancerSolid Tumor+12 more
Parabilis Medicines, Inc. 595
Testing effectiveness (Phase 2)Looking for participantsNCT05959356
What this trial is testing

Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Sun Yat-sen University 198
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Testing effectiveness (Phase 2)Study completedNCT03800602
What this trial is testing

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaRefractory Colorectal Carcinoma+5 more
Emory University 29
Testing effectiveness (Phase 2)Looking for participantsNCT05985109
What this trial is testing

KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Peking University Cancer Hospital & Institute 98
Testing effectiveness (Phase 2)Study completedNCT03832621
What this trial is testing

NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Microsatellite Stable, MGMT Silenced Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 135
Testing effectiveness (Phase 2)Active Not RecruitingNCT06124378
What this trial is testing

Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer

Who this might be right for
Colonic NeoplasmsNeoadjuvant TherapyImmune Checkpoint Inhibitors
First Affiliated Hospital of Guangxi Medical University 60
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