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Results for “MSS, Microsatellite Stable Colon Cancer”

74 trials

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Showing 20 of 74 results

Early research (Phase 1)Ended earlyNCT04044430
What this trial is testing

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+25 more
University of California, San Francisco 2
Testing effectiveness (Phase 2)Study completedNCT04126733
What this trial is testing

Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)

Who this might be right for
Colorectal Cancer
Bayer 70
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07229872
What this trial is testing

A Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Fruquintinib in the Treatment of Immunodominant pMMR/MSS Metastatic Colorectal Cancer That Has Failed Second-line or Above Treatment

Who this might be right for
Colorectal Cancer
Harbin Medical University 18
Testing effectiveness (Phase 2)Looking for participantsNCT06699836
What this trial is testing

Leronlimab in Combination With TAS-102 + Bevacizumab in Previously Treated Participants With mCRC

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
CytoDyn, Inc. 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05205330
What this trial is testing

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

Who this might be right for
Refractory Metastatic Colorectal CancerSolid TumorMetastatic Microsatellite-stable Colorectal Cancer+3 more
Rottapharm Biotech 107
Testing effectiveness (Phase 2)Looking for participantsNCT06522919
What this trial is testing

Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticMicrosatellite Stable Colorectal CarcinomaRefractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Post-approval studies (Phase 4)UnknownNCT02887365
What this trial is testing

A Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon Cancer

Who this might be right for
MSI-L/MSSStage II Colon Cancer
National Taiwan University Hospital 300
Early research (Phase 1)Study completedNCT03005002
What this trial is testing

Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the Liver

Who this might be right for
Metastatic Carcinoma in the LiverMLH1 Gene MutationMSH6 Gene Mutation+4 more
City of Hope Medical Center 9
Early research (Phase 1)Active Not RecruitingNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Testing effectiveness (Phase 2)Study completedNCT03642067
What this trial is testing

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal AdenocarcinomasColorectal Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 59
Testing effectiveness (Phase 2)WithdrawnNCT05730673
What this trial is testing

Leronlimab in Combination With Regorafenib in Patients With CCR5+, Metastatic Colorectal Cancer

Who this might be right for
CCR5Microsatellite StableMetastatic+1 more
CytoDyn, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06567782
What this trial is testing

Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer

Who this might be right for
Neoplasms, Colon
GlaxoSmithKline 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT05608044
What this trial is testing

Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Agenus Inc. 234
Early research (Phase 1)WithdrawnNCT03802747
What this trial is testing

Immunotherapy Combined With Y-90 and SBRT for Colorectal Liver Metastases

Who this might be right for
Colorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Ended earlyNCT03791398
What this trial is testing

BrUOG 379 Phase Ib/II Trial ONC201 + Nivolumab in MSS mCRC

Who this might be right for
Metastatic Colorectal Cancer
Brown University 13
Testing effectiveness (Phase 2)Ended earlyNCT03207867
What this trial is testing

NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

Who this might be right for
NSCLC, Non Small Cell Lung CancerRCC, Renal Cell CancerPancreatic Cancer+7 more
Novartis Pharmaceuticals 315
Testing effectiveness (Phase 2)Ended earlyNCT05733611
What this trial is testing

RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Replimune Inc. 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT04963283
What this trial is testing

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaColon CancerColon Adenocarcinoma+4 more
University of Colorado, Denver 48
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06594692
What this trial is testing

Node-Sparing Short-Course Radiation with CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: a Randomized, Prospective, Multicenter Study

Who this might be right for
Microsatellite Stable (MSS) Colon CancerLocally Advanced Colon Cancer
Sir Run Run Shaw Hospital 140
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