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Results for “Macitentan”

62 trials

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Showing 20 of 62 results

Not applicableStudy completedNCT01266265
What this trial is testing

Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies

Who this might be right for
Pulmonary Arterial Hypertension
United Therapeutics 1,333
Very early researchLooking for participantsNCT06811831
What this trial is testing

Evaluation of the Efficacy of MACitentan in the Treatment of CoronaryMICrovascular Angina (MACMIC)

Who this might be right for
Coronary Microvascular AnginaMacitentan
China-Japan Friendship Hospital 30
Large-scale testing (Phase 3)Study completedNCT02932410
What this trial is testing

Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 165
Early research (Phase 1)Study completedNCT03359291
What this trial is testing

Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects

Who this might be right for
Healthy Subjects
Actelion 20
Large-scale testing (Phase 3)Study completedNCT01841762
What this trial is testing

Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 284
Post-approval studies (Phase 4)Ended earlyNCT02968901
What this trial is testing

Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA)

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 46
Early research (Phase 1)Study completedNCT02476864
What this trial is testing

Comparison of the Pharmacokinetic Properties of Two Tablet Formulations of Macitentan in Healthy Adults

Who this might be right for
Healthy Subjects
Actelion 12
Early research (Phase 1)Study completedNCT03215966
What this trial is testing

Compare the Macitentan-tadalafil Fixed Dose Combination Tablet Relative to the Concomitant Administration of the Reference Tablets of Macitentan and Tadalafil in Healthy Subjects

Who this might be right for
Healthy Subjects
Actelion 38
Testing effectiveness (Phase 2)Study completedNCT02554903
What this trial is testing

Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation

Who this might be right for
Pulmonary Hypertension
Actelion 57
Post-approval studies (Phase 4)Looking for participantsNCT07147114
What this trial is testing

Clinical Trial to Evaluate the Efficacy and Safety in Concomitant Administration of Macitentan and Dapagliflozin in Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction (HFmrEF and HFpEF) and Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH)

Who this might be right for
Combined Pre- and Post-capillary Pulmonary HypertensionCpcPHHFmrEF+2 more
Gachon University Gil Medical Center 64
Testing effectiveness (Phase 2)Study completedNCT02070991
What this trial is testing

Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction

Who this might be right for
Pulmonary Hypertension
Actelion 63
Early research (Phase 1)Study completedNCT06553937
What this trial is testing

Bioequivalence Study of Macitentan and Tadalafil Film-coated Tablets 10 Mg/40 Mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 Mg/40 Mg

Who this might be right for
PAH
Humanis Saglık Anonim Sirketi 30
Early research (Phase 1)Ended earlyNCT01499251
What this trial is testing

Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma

Who this might be right for
Glioblastoma
Actelion 75
Large-scale testing (Phase 3)WithdrawnNCT05946811
What this trial is testing

Macitentan to Prevent PRVO

Who this might be right for
Pulmonary Embolism
University of Maryland, Baltimore
Not applicableUnknownNCT03045666
What this trial is testing

Impact of Rehabilitation Program on PAH Patients Treated With Macitentan.

Who this might be right for
Pulmonary Arterial Hypertension
Soroka University Medical Center 48
Large-scale testing (Phase 3)Study completedNCT03904693
What this trial is testing

Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)

Who this might be right for
Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
Actelion 187
Not applicableStudy completedNCT02126943
What this trial is testing

OPsumit USers Registry

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 2,686
Large-scale testing (Phase 3)Ended earlyNCT03775421
What this trial is testing

An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients.

Who this might be right for
Congenital Heart Disease With Fontan Circulation
Actelion 112
Testing effectiveness (Phase 2)Ended earlyNCT02651272
What this trial is testing

Macitentan in Pulmonary Hypertension of Sickle Cell Disease

Who this might be right for
Pulmonary HypertensionSickle Cell Disease
Boston University 4
Large-scale testing (Phase 3)Ended earlyNCT01474122
What this trial is testing

Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients

Who this might be right for
Digital Ulcers
Actelion 265
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