Testing effectiveness (Phase 2)Study completedNCT00903331What this trial is testingMacitentan Use in an Idiopathic Pulmonary Fibrosis Clinical StudyWho this might be right forIdiopathic Pulmonary Fibrosis Actelion 178
Early research (Phase 1)Study completedNCT02476864What this trial is testingComparison of the Pharmacokinetic Properties of Two Tablet Formulations of Macitentan in Healthy AdultsWho this might be right forHealthy Subjects Actelion 12
Early research (Phase 1)Study completedNCT04211272What this trial is testingA 2-part Study to Investigate the Effect of Macitentan in Healthy Male ParticipantsWho this might be right forHealthy Actelion 47
Large-scale testing (Phase 3)WithdrawnNCT05946811What this trial is testingMacitentan to Prevent PRVOWho this might be right forPulmonary Embolism University of Maryland, Baltimore
Early research (Phase 1)WithdrawnNCT05731492What this trial is testingMacitentan in Children Below 2 Years of AgeWho this might be right forArterial Hypertension, Pulmonary Actelion
Not applicableUnknownNCT03045666What this trial is testingImpact of Rehabilitation Program on PAH Patients Treated With Macitentan.Who this might be right forPulmonary Arterial Hypertension Soroka University Medical Center 48
Early research (Phase 1)Study completedNCT04500808What this trial is testingMacitentan, in Healthy Japanese Male ParticipantsWho this might be right forHealthy Janssen Pharmaceutical K.K. 24
Large-scale testing (Phase 3)Ended earlyNCT03809650What this trial is testingA Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH).Who this might be right forChronic Thromboembolic Pulmonary Hypertension (CTEPH) Actelion 9
Very early researchLooking for participantsNCT06811831What this trial is testingEvaluation of the Efficacy of MACitentan in the Treatment of CoronaryMICrovascular Angina (MACMIC)Who this might be right forCoronary Microvascular AnginaMacitentan China-Japan Friendship Hospital 30
Large-scale testing (Phase 3)Study completedNCT01743001What this trial is testingClinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger SyndromeWho this might be right forPulmonary Arterial Hypertension Actelion 226
Early research (Phase 1)Study completedNCT06553924What this trial is testingMacitentan and Tadalafil Film-coated Tablets 10 mg/40 mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 mg/40 mgWho this might be right forPAH Humanis Saglık Anonim Sirketi 30
Early research (Phase 1)Study completedNCT03359291What this trial is testingClinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male SubjectsWho this might be right forHealthy Subjects Actelion 20
Large-scale testing (Phase 3)Ended earlyNCT01739400What this trial is testingClinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger SyndromeWho this might be right forPulmonary Arterial Hypertension Actelion 217
Testing effectiveness (Phase 2)Study completedNCT02021292What this trial is testingClinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary HypertensionWho this might be right forChronic Thromboembolic Pulmonary Hypertension Actelion 80
Early research (Phase 1)Study completedNCT02050802What this trial is testingStudy to Assess the Effect of Macitentan on the Electrocardiogram (ECG) in Healthy Male and Female SubjectsWho this might be right forHealthy Actelion 64
Large-scale testing (Phase 3)Study completedNCT01474109What this trial is testingMacitentan for the Treatment of Digital Ulcers in Systemic Sclerosis PatientsWho this might be right forSystemic SclerosisUlcers Actelion 289
Large-scale testing (Phase 3)Study completedNCT01841762What this trial is testingClinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT InstrumentWho this might be right forPulmonary Arterial Hypertension Actelion 284
Early research (Phase 1)Study completedNCT04235270What this trial is testingMacitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult ParticipantsWho this might be right forHealthy Janssen Research & Development, LLC 62
Early research (Phase 1)Ended earlyNCT01499251What this trial is testingClinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent GlioblastomaWho this might be right forGlioblastoma Actelion 75
Post-approval studies (Phase 4)Ended earlyNCT02968901What this trial is testingClinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA)Who this might be right forPulmonary Arterial Hypertension Actelion 46