Not applicableUnknownNCT05656833What this trial is testingCombination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial MelasmaWho this might be right forMelasma UnionDerm 20
Not applicableLooking for participantsNCT07540702What this trial is testingInjectable Platelet-Rich Fibrin Versus Intradermal Tranexamic Acid for MelasmaWho this might be right forMelasmaFacial Melasma Kasr El Aini Hospital 21
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07779811What this trial is testingTopical Metformin Versus Triple Regimen for Epidermal MelasmaWho this might be right forEpidermal MelasmaFacial Hyperpigmentation Combined Military Hospital, Pakistan 104
Not applicableLooking for participantsNCT07769268What this trial is testingEfficacy Evaluation of a Cosmetic Product for Facial HyperpigmentationWho this might be right forHyperpigmentationMelasma (Facial Melasma) Brainfarma Industria Química e Farmacêutica S/A 40
Not applicableUnknownNCT05911698What this trial is testingFractional co2 Laser Followed by Either Vitamin c or Tranexamic Acid in Treatment of Melasma.Who this might be right forMelasma Khadija Qenawi 25
Post-approval studies (Phase 4)Ended earlyNCT00669071What this trial is testingTreatment w/ Tri-Luma® Cream & Intense Pulsed Light (IPL) vs a Mild Inactive Control Cream & Intense Pulsed Light (IPL) in MelasmaWho this might be right forMelasma Galderma R&D 56
Post-approval studies (Phase 4)Study completedNCT00616239What this trial is testingSalicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic WomenWho this might be right forMelasma University of Texas Southwestern Medical Center 20
Not applicableStudy completedNCT07327983What this trial is testingAzelaic Acid 20% vs Hydroquinone 4% in Epidermal MelasmaWho this might be right forMelasmaMelasma (Facial Melasma) Gujranwala medical college District Headquarters Hospital, Gujranwala 146
Post-approval studies (Phase 4)Study completedNCT07508098What this trial is testingComparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of MelasmaWho this might be right forMelasma (Facial Melasma) Pak Emirates Military Hospital 50
Not applicableUnknownNCT04765930What this trial is testingCombined Q-switched Nd:YAG Laser and Platelet Rich Plasma Versus Q- Switched Nd:YAG Laser Alone in MelasmaWho this might be right forHyperpigmentationMelasmaPRP+1 more Cairo University 30
Post-approval studies (Phase 4)UnknownNCT03686787What this trial is testingOral Tranexamic Acid and Laser for Treatment of MelasmaWho this might be right forMelasma Laser and Skin Surgery Center of New York 32
Testing effectiveness (Phase 2)Study completedNCT01085279What this trial is testingFractional Laser as Treatment Option for Various Pigment Disorders (Fractional-3)Who this might be right forPigmentation Disorder Netherlands Institute for Pigment Disorders 29
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07169383What this trial is testingOral Melatonin Versus Oral Tranexamic Acid in the Management of MelasmaWho this might be right forMelasma (Facial Melasma) Hina Malik 160
Not applicableStudy completedNCT02977507What this trial is testingSplit-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial MelasmaWho this might be right forMelasma Allergan 18
Large-scale testing (Phase 3)Temporarily pausedNCT00717652What this trial is testingEfficiency And Safety Of Association Arbutin, Triamcinolone And Tretinoin In Treatment Of MelasmaWho this might be right forMelasma Azidus Brasil 110
Not applicableStudy completedNCT00509977What this trial is testingStudy of Light Treatment and Laser Treatment for MelasmaWho this might be right forMelasma Northwestern University 17
Not applicableEnrolling By InvitationNCT07296549What this trial is testingExpert Consensus on the Clinical Management of Melasma: A Delphi Method StudyWho this might be right forMelasmaMelasma (Facial Melasma) Venus Research Center 15
Post-approval studies (Phase 4)UnknownNCT03923062What this trial is testingDifferent Dermatological Approaches the Treatment of MelasmaWho this might be right forMelasma Assiut University 40
Not applicableStudy completedNCT07722351What this trial is testingHomocysteic Acid Biostimulator for Photoaged Facial SkinWho this might be right forSkin AgingHyperpigmentation Medical University of Silesia 25
Not applicableLooking for participantsNCT07679945What this trial is testingA Clinical Study to Evaluate the Efficacy in Improving Dark Spots After 8 Weeks of Use of Facial Sunscreens in Adult ParticipantsWho this might be right forPost-inflammatory HyperpigmentationMelasmaSolar Lentigo Kenvue Brands LLC 152