Testing effectiveness (Phase 2)Looking for participantsNCT03667170What this trial is testingKN035 for dMMR/MSI-H Advanced Solid TumorsWho this might be right forSolid Tumor 3D Medicines (Sichuan) Co., Ltd. 200
Testing effectiveness (Phase 2)Looking for participantsNCT06903858What this trial is testingToripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal CancerWho this might be right forColorectal CancerMicrosatellite Instability HighMismatch Repair Deficiency Sun Yat-sen University 105
Testing effectiveness (Phase 2)UnknownNCT04262687What this trial is testingChemotherapy and Immunotherapy as Treatment for MSS Metastatic Colorectal Cancer With High Immune InfiltrateWho this might be right forColorectal Cancer MetastaticHigh Immune InfiltrateMicrosatellite Stable Federation Francophone de Cancerologie Digestive 55
Testing effectiveness (Phase 2)Looking for participantsNCT04114136What this trial is testingAnti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor MalignanciesWho this might be right forMelanomaNSCLCHepatocellular Carcinoma+5 more Dan Zandberg 72
Not applicableStudy completedNCT03495674What this trial is testingCycling in Preventing Colorectal Cancer in Participants With Lynch SyndromeWho this might be right forHigh-Frequency Microsatellite InstabilityMismatch Repair Gene MutationMutation-Negative Lynch Syndrome+1 more M.D. Anderson Cancer Center 21
Testing effectiveness (Phase 2)Looking for participantsNCT04774419What this trial is testingRadiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive SurgeryWho this might be right forEndometrial Cancer Memorial Sloan Kettering Cancer Center 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT03836352What this trial is testingStudy of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid TumorsWho this might be right forOvarian CancerHepatocellular CarcinomaNon-small Cell Lung Cancer+2 more ImmunoVaccine Technologies, Inc. (IMV Inc.) 184
Early research (Phase 1)Ended earlyNCT04234113What this trial is testingStudy of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid TumorsWho this might be right forThyroid CancerRenal Cell CarcinomaNon Small Cell Lung Cancer+16 more SOTIO Biotech AG 115
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06426654What this trial is testingSintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric CancerWho this might be right forGastric Cancer West China Hospital 45
Early research (Phase 1)Active Not RecruitingNCT03589339What this trial is testingNBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 TherapyWho this might be right forRadiotherapyImmunotherapyMicrosatellite Instability-High Solid Malignant Tumour+8 more Nanobiotix 145
Large-scale testing (Phase 3)Looking for participantsNCT06762405What this trial is testingPRODIGE 90 - (FFCD 2204) Neoadjuvant Dostarlimab with Short Course Radiotherapy in a Watch-and-wait Strategy for Microsatellite Unstable or Mismatch Repair-deficient Locally Advanced Rectal Cancer PatientsWho this might be right forRectal Adenocarcinoma with Mismatch-repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Centre Hospitalier Universitaire Dijon 68
Testing effectiveness (Phase 2)Active Not RecruitingNCT06710847What this trial is testingInvestigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid TumorsWho this might be right forNeoplasms, ColorectalSolid TumorColon Cancer+2 more GlaxoSmithKline 14
Large-scale testing (Phase 3)Active Not RecruitingNCT05652894What this trial is testingHX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal CancerWho this might be right forMetastatic Colorectal Cancer Taizhou Hanzhong biomedical co. LTD 190
Testing effectiveness (Phase 2)Ended earlyNCT04258111What this trial is testingIBI310 in Combination with Sintilimab in Patients with DNA Mismatch Repair Deficient (dMMR)/microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal CancerWho this might be right forColorectal Cancer Innovent Biologics (Suzhou) Co. Ltd. 4
Large-scale testing (Phase 3)Looking for participantsNCT06686576What this trial is testingNeoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon CancerWho this might be right forColon Cancer Qilu Pharmaceutical Co., Ltd. 363
Early research (Phase 1)Active Not RecruitingNCT05838768What this trial is testingStudy of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.Who this might be right forMSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers Novartis Pharmaceuticals 123
Testing effectiveness (Phase 2)Ended earlyNCT03277352What this trial is testingINCAGN01876 in Combination With Immune Therapies in Subjects With Advanced or Metastatic MalignanciesWho this might be right forAdvanced MalignanciesMetastatic Cancer Incyte Biosciences International Sàrl 10
Testing effectiveness (Phase 2)UnknownNCT04326829What this trial is testingQL1604 Monotherapy for dMMR or MSI-H Advanced Solid TumorsWho this might be right forAdvanced Malignant Tumor Qilu Pharmaceutical Co., Ltd. 86
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06646445What this trial is testingNeoadjuvant Pembrolizumab With a Watch-and-wait Strategy for dMMR/MSI-H Localized Colon Cancer: PREMICES Study.Who this might be right forColon Cancer GERCOR - Multidisciplinary Oncology Cooperative Group 60
Testing effectiveness (Phase 2)Looking for participantsNCT07213609What this trial is testingInvestigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid TumorsWho this might be right forNeoplasms, ColorectalNeoplasms GlaxoSmithKline 47