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Results for “Monotherapy”

3,098 trials

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Showing 20 of 3,098 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT06927232
What this trial is testing

AZA+Lus VS AZA Monotherapy in HR-MDS

Who this might be right for
Higher-risk Myelodysplastic Syndrome
Peking Union Medical College Hospital 86
Large-scale testing (Phase 3)UnknownNCT03236584
What this trial is testing

Tenofovir Monotherapy in Patients With Chronic Hepatitis B Patients Who Had Achieved Complete Viral Suppression on Lamivudine Plus Adefovir

Who this might be right for
Proportion of Patients With a Sustained Virological Response (Serum HBV DNA <20 IU/mL) at Week 48
Uijeongbu St. Mary Hospital 76
Post-approval studies (Phase 4)Study completedNCT02953938
What this trial is testing

Study to Show a Superior Benefit in Terms of Reduction of Ranibizumab Injections in Patients Receiving Ranibizumab Plus Laser Photocoagulation Combination Therapy Without Loss of Efficacy and Safety

Who this might be right for
Macular Edema Secondary to Branch Retinal Vein Occlusion (BRVO)
Novartis Pharmaceuticals 59
Early research (Phase 1)Ended earlyNCT02862535
What this trial is testing

Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Anti-Cancer Agents in Japanese Participants With Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Adenocarcinoma
Gilead Sciences 36
Early research (Phase 1)Ended earlyNCT04835714
What this trial is testing

Find a Safe and Effective Dose of BI 1701963 Alone and in Combination With BI 3011441 in Patients With Advanced Cancer and a Certain Mutation (Kirsten Rat Sarcoma Viral Oncogene Homologue [KRAS])

Who this might be right for
Solid Tumors, KRAS Mutation
Boehringer Ingelheim 8
Testing effectiveness (Phase 2)Ended earlyNCT04082936
What this trial is testing

Imvotamab Monotherapy and in Combination in Subjects With Relapsed/Refractory Non-Hodgkin Lymphoma

Who this might be right for
Non-Hodgkin LymphomaFollicular LymphomaDLBCL+2 more
IGM Biosciences, Inc. 97
Large-scale testing (Phase 3)Study completedNCT02231749
What this trial is testing

Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214)

Who this might be right for
Advanced Renal Cell CarcinomaMetastatic Renal Cell Carcinoma
Bristol-Myers Squibb 1,390
Early research (Phase 1)Active Not RecruitingNCT05614102
What this trial is testing

A First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bayer 284
Testing effectiveness (Phase 2)Study completedNCT04445701
What this trial is testing

Study of AO-176 as Monotherapy and in Combination With Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Arch Oncology 10
Testing effectiveness (Phase 2)Study completedNCT00777049
What this trial is testing

Study of Panobinostat Monotherapy in Women With HER2-negative Locally Recurrent or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Translational Research in Oncology 54
Testing effectiveness (Phase 2)Study completedNCT01412892
What this trial is testing

Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaNeurofibromatoses
Assistance Publique - Hôpitaux de Paris 30
Large-scale testing (Phase 3)Looking for participantsNCT06614192
What this trial is testing

A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
AbbVie 460
Testing effectiveness (Phase 2)Looking for participantsNCT04669171
What this trial is testing

A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma

Who this might be right for
Follicular LymphomaMarginal Zone Lymphoma
Enterome 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT06550336
What this trial is testing

A Clinical Study Assessing the Efficacy of Chidamide for CD30-positive Peripheral T-cell Lymphoma (PTCL).

Who this might be right for
Peripheral T Cell Lymphoma
The First Hospital of Jilin University 35
Testing effectiveness (Phase 2)Study completedNCT01511198
What this trial is testing

Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent

Who this might be right for
DiabetesDiabetes Mellitus, Type 2
Novo Nordisk A/S 223
Early research (Phase 1)Study completedNCT05501821
What this trial is testing

Study of KBA1412 in Participants With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Tumor Malignancy
Kling Biotherapeutics B.V. 16
Post-approval studies (Phase 4)Study completedNCT00650663
What this trial is testing

Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377)

Who this might be right for
HypercholesterolemiaAtherosclerosis
Organon and Co 247
Testing effectiveness (Phase 2)Study completedNCT03819647
What this trial is testing

Evaluation of the Efficacy of Stiripentol (Diacomit) as Monotherapy for the Treatment of Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria
Biocodex 15
Testing effectiveness (Phase 2)Study completedNCT02320058
What this trial is testing

An Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by Itself

Who this might be right for
Melanoma
Bristol-Myers Squibb 119
Early research (Phase 1)Study completedNCT03009214
What this trial is testing

A Safety and Pharmacokinetic Phase I/Ib Study of AMC303 in Patients With Solid Tumours

Who this might be right for
Malignant Solid Tumor
amcure GmbH 55
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