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Results for “Myelodysplastic Syndrome (MDS) - High and Intermediate Risk”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02935361
What this trial is testing

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
University of Southern California 33
Testing effectiveness (Phase 2)Ended earlyNCT03946670
What this trial is testing

MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).

Who this might be right for
Myelodysplastic Syndromes
Novartis Pharmaceuticals 127
Testing effectiveness (Phase 2)WithdrawnNCT00867061
What this trial is testing

Efficacy and Safety of 5-day Dosing of ON 01910.Na in Intermediate-1,-2, or High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Myelodysplastic Syndrome
Traws Pharma, Inc.
Early research (Phase 1)Study completedNCT04402541
What this trial is testing

Study of CB-5339 in Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia, in RelapseMyelodysplastic Syndromes
Cleave Therapeutics, Inc. 55
Large-scale testing (Phase 3)Ended earlyNCT04266301
What this trial is testing

Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2)

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, Chronic
Novartis Pharmaceuticals 530
Testing effectiveness (Phase 2)Study completedNCT00744536
What this trial is testing

Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDS

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicAngiogenesis
Sunnybrook Health Sciences Centre 20
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Testing effectiveness (Phase 2)Study completedNCT00439673
What this trial is testing

PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS

Who this might be right for
Myelodysplastic Syndromes
Gruppo Italiano Malattie EMatologiche dell'Adulto 62
Large-scale testing (Phase 3)Not Yet RecruitingNCT07722988
What this trial is testing

Investigate the Efficacy and Safety of Roxadustat (FG-4592) for Treating Anemia in Participants With Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndromes
Kyntra Bio 201
Testing effectiveness (Phase 2)WithdrawnNCT05829434
What this trial is testing

Magrolimab Plus Intensive Chemotherapy in Newly Diagnosed AML or HR-MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Neoplasm
Uwe Platzbecker
Early research (Phase 1)Study completedNCT02485535
What this trial is testing

Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant

Who this might be right for
Acute Myeloid Leukemiade Novo Myelodysplastic SyndromeMyelodysplastic Syndrome+2 more
University of Chicago 12
Large-scale testing (Phase 3)Ended earlyNCT02158936
What this trial is testing

Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Thrombocytopaenia
Novartis Pharmaceuticals 356
Large-scale testing (Phase 3)Active Not RecruitingNCT05883956
What this trial is testing

A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myeloid, AcuteLeukemia, Myelomonocytic, Chronic+1 more
Otsuka Australia Pharmaceutical Pty Ltd 13
Testing effectiveness (Phase 2)Study completedNCT02649790
What this trial is testing

Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications

Who this might be right for
Relapsed/Refractory Multiple Myeloma (RRMM)Metastatic Colorectal Cancer (mCRC)Metastatic Castration-Resistant Prostate Cancer (mCRPC)+3 more
Karyopharm Therapeutics Inc 277
Testing effectiveness (Phase 2)Study completedNCT02018926
What this trial is testing

Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS

Who this might be right for
Myelodysplastic Syndrome
Mirati Therapeutics Inc. 18
Early research (Phase 1)WithdrawnNCT03057990
What this trial is testing

Pyrimethamine for Intermediate/High-risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndromes
Montefiore Medical Center
Testing effectiveness (Phase 2)Study completedNCT01980056
What this trial is testing

Vosaroxin for Intermediate 2 or High-risk MDS After Failure With Hypomethylating Agent-based Therapy

Who this might be right for
Myelodysplastic Syndrome
Weill Medical College of Cornell University 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07616336
What this trial is testing

Chidamide Monotherapy for Intermediate-to-High-Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Zhongshan Hospital (Xiamen), Fudan University 15
Testing effectiveness (Phase 2)Study completedNCT01873703
What this trial is testing

Phase 2 Study of Pracinostat With Azacitidine in Patients With Previously Untreated Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndrome
Helsinn Healthcare SA 102
Large-scale testing (Phase 3)UnknownNCT05175508
What this trial is testing

Aza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS

Who this might be right for
AMLMDSOld Age; Debility+1 more
The First Affiliated Hospital of Soochow University 180
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