Large-scale testing (Phase 3)Study completedNCT01421992What this trial is testingMethylphenidate in Myotonic Dystrophy Type 1Who this might be right forDystrophia Myotonica 1 Laval University 28
Not applicableLooking for participantsNCT04003363What this trial is testingThe United Kingdom National Registry for Myotonic DystrophyWho this might be right forMyotonic Dystrophy Newcastle University 900
Large-scale testing (Phase 3)Enrolling By InvitationNCT06549400What this trial is testingAn Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2 Who Have Completed MEX-DM-302 Study.Who this might be right forMyotonic Dystrophy Lupin Ltd. 176
Large-scale testing (Phase 3)Looking for participantsNCT07486934What this trial is testingEfficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy Type 1 (DM1)DM1Myotonic Dystrophy+2 more Dyne Therapeutics 150
Testing effectiveness (Phase 2)Study completedNCT01406873What this trial is testingClinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy University of Rochester 42
Not applicableStudy completedNCT05400629What this trial is testingEffects of a 12-week Strength Training Program in Women With Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy 1 Université de Sherbrooke 12
Testing effectiveness (Phase 2)Study completedNCT04886518What this trial is testingSafety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy 1Excessive Daytime Sleepiness Harmony Biosciences Management, Inc. 30
Not applicableStudy completedNCT07362316What this trial is testingLongitudinal Evaluation of Neuromuscular Involvement in Type 1 Myotonic DystrophyWho this might be right forSteinert Myotonic Dystrophy Institut de Myologie, France 50
Testing effectiveness (Phase 2)Looking for participantsNCT06844214What this trial is testingInvestigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 55 Years of Age With Non-congenital Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy Sanofi 32
Not applicableStudy completedNCT03589677What this trial is testingBrain Involvement in Myotonic Dystrophy Type I: From Functional Neuroimaging to the Impact on Quality of LifeWho this might be right forMyotonic Dystrophy Type 1 (DM1) IRCCS San Camillo, Venezia, Italy 50
Large-scale testing (Phase 3)Study completedNCT01939561What this trial is testingLamotrigine as Treatment of MyotoniaWho this might be right forDystrophia Myotonica Type 1Myotonia CongenitaParamyotonia Congenita+2 more Grete Andersen, MD 27
Not applicableStudy completedNCT04187482What this trial is testingMyotonic Dystrophy Type 1 Aerobic Exercise StudyWho this might be right forMyotonic Dystrophy 1Muscular Dystrophies McMaster University 13
Early research (Phase 1)Study completedNCT02251457What this trial is testingStudy of Ranolazine in Myotonia Congenita, Paramyotonia Congenita and Myotonic Dystrophy Type 1Who this might be right forMyotonia CongenitaParamyotonia CongenitaMyotonic Dystrophy 1 Ohio State University 35
Not applicableStudy completedNCT01136330What this trial is testingDM1 Heart Registry - DM1 Respiratory RegistryWho this might be right forMyotonic Dystrophy Institut de Myologie, France 914
Not applicableUnknownNCT06378216What this trial is testingMyotonic Dystrophy Type 1 Congenital and Juvenile Form: From Diagnosis to Rehabilitation [MDCJ-NeuBeRe]Who this might be right forMyotonic Dystrophy 1 IRCCS Eugenio Medea 30
Testing effectiveness (Phase 2)Looking for participantsNCT07220603What this trial is testingAn Open-Label Extension Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1 (FREEDOM-OLE)Who this might be right forMyotonic Dystrophy 1 PepGen Inc 48
Large-scale testing (Phase 3)UnknownNCT05848830What this trial is testingHome-based Training and Supplementation in DM1 PatientsWho this might be right forMyotonic Dystrophy 1 McMaster University 60
Not applicableStudy completedNCT04634682What this trial is testingEffect of MYODM on Quality of Life, Fatigue and Hypersomnia in Patients With Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy 1 Myogem Health Company, S.L. 30
Testing effectiveness (Phase 2)Looking for participantsNCT06667453What this trial is testingA Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy 1 PepGen Inc 24
Not applicableStudy completedNCT05006924What this trial is testingSymptoms and Outcome Measures for Upper- Limb Function in Myotonic Dystrophy Type 1Who this might be right forMyotonic Dystrophy 1 Oslo University Hospital 89