Post-approval studies (Phase 4)Study completedNCT04979247What this trial is testingIntravenous Oliceridine and Opioid-related ComplicationsWho this might be right forMajor Surgery The Cleveland Clinic 111
Early research (Phase 1)Study completedNCT02083315What this trial is testingPharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy SubjectsWho this might be right forPain, Acute Trevena Inc. 30
Testing effectiveness (Phase 2)Ended earlyNCT02520297What this trial is testingA Pilot Study of TRV130 for the Treatment of Fracture PainWho this might be right forPain Trevena Inc. 1
Not applicableStudy completedNCT07372209What this trial is testingEffects and Safety of Oliceridine in Anesthesia Induction:A Randomised Controlled TrialWho this might be right forGynecological Laparoscopic SurgeryGeneral AnestheticIntubation Tangshan Maternal and Child Health Hospital 120
Not applicableNot Yet RecruitingNCT06668298What this trial is testingClinical Study of G Protein Biased Μ - Opioid Receptor Agonist Oliceridine for Optimizing Postoperative Analgesia Under General AnesthesiaWho this might be right forOld Age Henan Provincial People's Hospital 150
Post-approval studies (Phase 4)Study completedNCT06458400What this trial is testingTo Evaluate the Efficacy and Safety of Tegileridine and Oliceridine Injections in the Treatment of Postoperative PainWho this might be right forAnalgesia Yuwei Qiu 75
Not applicableStudy completedNCT07154979What this trial is testingOliceridine Dose for Tracheal Intubation Hemodynamic Elevation: Up-and-Down TrialWho this might be right forOliceridine Shiyou Wei 58
Post-approval studies (Phase 4)Looking for participantsNCT06320041What this trial is testingEfficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic SurgeryWho this might be right forPostoperative Pain The Fourth Affiliated Hospital of Zhejiang University School of Medicine 162
Post-approval studies (Phase 4)Not Yet RecruitingNCT06619145What this trial is testing1.Comparison of the Analgesic Effect of Remifentanil Group and Different Dose Groups of Oliceridine in Postoperative Patients Undergoing Cardiac Surgery 2.Exploring the Hemodynamic Effects of Analgesic Regimens With Different Doses of Oliceridine After Cardiac SurgeryWho this might be right forOliceridinePostoperative Cardiac Surgery Nanjing First Hospital, Nanjing Medical University 270
Testing effectiveness (Phase 2)Study completedNCT02100748What this trial is testingTRV130 for the Treatment of Pain After BunionectomyWho this might be right forAcute Pain Trevena Inc. 333
Early research (Phase 1)Study completedNCT02344303What this trial is testingStudy of the Effects of TRV130, at Therapeutic and Supra Therapeutic Doses, on QTc IntervalsWho this might be right forHealthy Trevena Inc. 63
Testing effectiveness (Phase 2)Study completedNCT02335294What this trial is testingTRV130 for the Treatment of Pain After AbdominoplastyWho this might be right forPain Trevena Inc. 200
Not applicableLooking for participantsNCT06409689What this trial is testingOliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid StudyWho this might be right forPostoperative Analgesia Tongji Hospital 80
Not applicableNot Yet RecruitingNCT07097038What this trial is testingAnalgesic Effect and Safety of Oliceridine and Oxycodone in VitrectomyWho this might be right forVitrectomy Henan Provincial People's Hospital 120
Post-approval studies (Phase 4)Looking for participantsNCT07026162What this trial is testingOliceridine on Postoperative Nausea and Vomiting in Gynecological Laparoscopic SurgeryWho this might be right forGynecologic Surgical ProceduresPostoperative Nausea and Vomiting (PONV)Laparoscopy YanYing Xiao 96
Post-approval studies (Phase 4)Not Yet RecruitingNCT07018375What this trial is testingThe Effect of Oliceridine Patient-Controlled Intravenous Analgesia on Postoperative Chronic Pain After Video-Assisted Thoracoscopic LobectomyWho this might be right forChronic Postsurgical Pain Tianjin Medical University General Hospital 320
Post-approval studies (Phase 4)Looking for participantsNCT06411665What this trial is testingEffect of Oliceridine Analgesia on Postoperative Nause and VomitingWho this might be right forPostoperative Nausea and Vomiting Peking University First Hospital 252
Not applicableNot Yet RecruitingNCT07307495What this trial is testingEffect of Postoperative Analgesia of Oliceridine Fumarate for Gastrointestinal Function Recovery in Patients Undergoing Lumbar Spine SurgeryWho this might be right forOliceridine Fumarate Xijing Hospital 428
Large-scale testing (Phase 3)Study completedNCT02815709What this trial is testingStudy of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After BunionectomyWho this might be right forAcute Pain Trevena Inc. 418
Early research (Phase 1)Study completedNCT02169934What this trial is testingInvestigate the Metabolism and Excretion of [14C]-TRV130 in Healthy Male SubjectsWho this might be right forHealthy Trevena Inc. 6