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Results for “Optic, Atrophy, Hereditary, Leber”

49 trials

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Showing 20 of 49 results

Testing effectiveness (Phase 2)Ended earlyNCT03913130
What this trial is testing

Extension Study to Study PQ-110-001 (NCT03140969)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 9
Large-scale testing (Phase 3)Study completedNCT02652767
What this trial is testing

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 39
Early research (Phase 1)Study completedNCT02161380
What this trial is testing

Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Byron Lam 28
Large-scale testing (Phase 3)Looking for participantsNCT06891443
What this trial is testing

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 32
Not applicableStudy completedNCT01421381
What this trial is testing

RHODOS Follow-up Single-visit Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 60
Not applicableNo Longer AvailableNCT02300753
What this trial is testing

Emergency Administration of EPI-743 to a Single Patient With Leber's Hereditary Optic Neuropathy [LHON]

Who this might be right for
Leber's Hereditary Optic Neuropathy
Edison Pharmaceuticals Inc
Not applicableStudy completedNCT01267422
What this trial is testing

Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber Hereditary Optic Neuropathy
Bin Li 9
Testing effectiveness (Phase 2)Study completedNCT00747487
What this trial is testing

Study to Assess Efficacy,Safety and Tolerability of Idebenone in the Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 85
Testing effectiveness (Phase 2)Ended earlyNCT01389817
What this trial is testing

Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Medical College of Wisconsin 4
Testing effectiveness (Phase 2)Study completedNCT02023866
What this trial is testing

Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease

Who this might be right for
Inherited Mitochondrial Disease, Including Leigh Syndrome
Amgen 36
Not applicableStudy completedNCT04909398
What this trial is testing

Pupil Dynamics and Color Vision for the Detection of Eye Diseases

Who this might be right for
Retinitis PigmentosaLeber's Hereditary Optic NeuropathyStargardt Disease
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts 60
Testing effectiveness (Phase 2)Study completedNCT02064569
What this trial is testing

Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 19
Not applicableLooking for participantsNCT02435940
What this trial is testing

Inherited Retinal Degenerative Disease Registry

Who this might be right for
Eye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more
Foundation Fighting Blindness 20,000
Not applicableNo Longer AvailableNCT04381091
What this trial is testing

Expanded Access Program for Idebenone in Patients With Leber's Hereditary Optic Neuropathy Who Completed the LEROS Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Testing effectiveness (Phase 2)Ended earlyNCT05820152
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 11
Testing effectiveness (Phase 2)UnknownNCT02176733
What this trial is testing

Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy
University Hospital, Angers 12
Large-scale testing (Phase 3)Study completedNCT00528151
What this trial is testing

A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Optic Atrophy, Hereditary, Leber
Mahidol University 70
Not applicableLooking for participantsNCT06682819
What this trial is testing

Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MétabOCT)

Who this might be right for
Healthy SubjectsLeber Hereditary Optic Neuropathy
Hôpital Necker-Enfants Malades 90
Large-scale testing (Phase 3)Study completedNCT02652780
What this trial is testing

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 37
Testing effectiveness (Phase 2)Ended earlyNCT02473445
What this trial is testing

A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Amgen 22
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