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Results for “Parkinson Disease, Secondary”

137 trials

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Showing 20 of 137 results

Early research (Phase 1)Study completedNCT02027961
What this trial is testing

Phase 1 Safety and Tolerability of MEDI4736 in Combination With Dabrafenib and Trametinib or With Trametinib Alone

Who this might be right for
Melanoma
MedImmune LLC 68
Testing effectiveness (Phase 2)Study completedNCT03322540
What this trial is testing

Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)

Who this might be right for
Lung Cancer
Incyte Corporation 154
Testing effectiveness (Phase 2)Ended earlyNCT04521621
What this trial is testing

Gebasaxturev (V937) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (V937-013)

Who this might be right for
Neoplasm Metastasis
Merck Sharp & Dohme LLC 76
Large-scale testing (Phase 3)Study completedNCT03829332
What this trial is testing

Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) in Adults With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Treatment-naïve Nonsmall Cell Lung Cancer (NSCLC) (MK-7902-007/E7080-G000-314/LEAP-007)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 623
Not applicableStudy completedNCT03516994
What this trial is testing

Reducing Disparities in the Quality of Advance Care Planning for Older Adults

Who this might be right for
Metastatic CancerCongestive Heart FailureChronic Obstructive Pulmonary Disease+6 more
Duke University 790
Large-scale testing (Phase 3)Study completedNCT03358472
What this trial is testing

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

Who this might be right for
Head and Neck Cancer
Incyte Corporation 89
Testing effectiveness (Phase 2)Study completedNCT03993353
What this trial is testing

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CarcinomaHead and Neck Carcinoma+9 more
University of California, San Diego 7
Large-scale testing (Phase 3)Study completedNCT03675737
What this trial is testing

Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-859/KEYNOTE-859)

Who this might be right for
Stomach Neoplasms
Merck Sharp & Dohme LLC 1,579
Large-scale testing (Phase 3)Looking for participantsNCT06312176
What this trial is testing

Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Who this might be right for
Breast Neoplasms
Merck Sharp & Dohme LLC 1,200
Early research (Phase 1)WithdrawnNCT03920839
What this trial is testing

INCMGA00012 Plus Chemotherapy in Participants With Advanced Solid Tumors (POD1UM-105)

Who this might be right for
Advanced and/or Metastatic Solid TumorsStage IIIB Not Amenable to Curative Therapy to Stage IV Non-small Cell Lung CancerAdvanced/Metastatic Unresectable Malignant Pleural Mesothelioma
Incyte Corporation
Testing effectiveness (Phase 2)Active Not RecruitingNCT05608044
What this trial is testing

Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Agenus Inc. 234
Large-scale testing (Phase 3)Study completedNCT03950674
What this trial is testing

Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension Study

Who this might be right for
Non-Small-Cell Lung Carcinoma
Merck Sharp & Dohme LLC 40
Large-scale testing (Phase 3)Study completedNCT03189719
What this trial is testing

First-line Esophageal Carcinoma Study With Pembrolizumab Plus Chemo vs. Chemo (MK-3475-590/KEYNOTE-590)

Who this might be right for
Esophageal Neoplasms
Merck Sharp & Dohme LLC 749
Not applicableStudy completedNCT04340492
What this trial is testing

Education for Adapted Physical Activity in Parkinson's Disease

Who this might be right for
Parkinson Disease
University Hospital, Lille 89
Testing effectiveness (Phase 2)Study completedNCT04191135
What this trial is testing

Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009)

Who this might be right for
Triple Negative Breast Neoplasms
Merck Sharp & Dohme LLC 462
Large-scale testing (Phase 3)Looking for participantsNCT06841354
What this trial is testing

Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Who this might be right for
Triple Negative Breast Neoplasms
Merck Sharp & Dohme LLC 1,000
Not applicableLooking for participantsNCT04071847
What this trial is testing

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Who this might be right for
Movement DisordersParkinson DiseaseEssential Tremor+4 more
Abbott Medical Devices 1,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT04626479
What this trial is testing

Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 400
Not applicableUnknownNCT02588924
What this trial is testing

Study on the Relationship Between Environmental and Occupational Exposure to Metals and Parkinson's Disease

Who this might be right for
Parkinson Disease, Secondary
University of Campania Luigi Vanvitelli 100
Not applicableEnded earlyNCT01886131
What this trial is testing

Motor Control During Rapid Eye Movement (REM) Sleep Behaviour Disorder

Who this might be right for
Parkinson Disease
University Hospital, Toulouse 3
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