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Results for “Participants With Mild Hepatic Impairment”

59 trials

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Showing 20 of 59 results

Early research (Phase 1)Study completedNCT05409911
What this trial is testing

Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants

Who this might be right for
Hepatic Impairment
Shionogi 25
Early research (Phase 1)Study completedNCT05882032
What this trial is testing

LY3502970 in Participants With Impaired and Normal Liver Function

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 29
Early research (Phase 1)Study completedNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 69
Early research (Phase 1)Study completedNCT06916078
What this trial is testing

Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function

Who this might be right for
Liver DysfunctionHealthy
Eli Lilly and Company 30
Early research (Phase 1)Ended earlyNCT05376839
What this trial is testing

Assess Safety of Cedirogant and How Cedirogant Moves Through the Body in Adult Participants With Mild, Moderate and Severe Hepatic Impairment

Who this might be right for
Hepatic Impairment
AbbVie 6
Early research (Phase 1)Study completedNCT06529796
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Focal Segmental Glomerulosclerosis (FSGS)
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Study completedNCT05560464
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Pain
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Ended earlyNCT05126329
What this trial is testing

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 13
Early research (Phase 1)Looking for participantsNCT07165002
What this trial is testing

The Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 32
Early research (Phase 1)WithdrawnNCT05490030
What this trial is testing

Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals
Early research (Phase 1)Study completedNCT07049939
What this trial is testing

Bomedemstat (MK-3543) in Participants With Mild or Moderate Hepatic Impairment (MK-3543-023)

Who this might be right for
Hepatic Insufficiency
Merck Sharp & Dohme LLC 9
Early research (Phase 1)Study completedNCT03920865
What this trial is testing

Investigate the Effect of Hepatic Impairment on the Pharmacokinetics and Safety and Tolerability of a Single Oral Dose of Risdiplam Compared to Matched Healthy Participants With Normal Hepatic Function

Who this might be right for
Muscular Atrophy, Spinal
Hoffmann-La Roche 26
Early research (Phase 1)Study completedNCT02910739
What this trial is testing

An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)

Who this might be right for
Amnestic Mild Cognitive ImpairmentAlzheimer's DiseaseProdromal Alzheimer's Disease
Merck Sharp & Dohme LLC 16
Early research (Phase 1)Study completedNCT07018492
What this trial is testing

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

Who this might be right for
Hepatic Impairment
Shionogi 32
Early research (Phase 1)Study completedNCT07198087
What this trial is testing

Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants

Who this might be right for
Primary Central Nervous System Lymphoma (PCNSL)
Ono Pharmaceutical Co., Ltd. 40
Early research (Phase 1)Study completedNCT01531309
What this trial is testing

Pharmacokinetics of AGO178 in Participants With Liver Impairment

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 32
Early research (Phase 1)Study completedNCT05718258
What this trial is testing

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 26
Early research (Phase 1)Study completedNCT03440424
What this trial is testing

Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects

Who this might be right for
Hepatic Impairment
Eisai Inc. 24
Early research (Phase 1)Study completedNCT01465412
What this trial is testing

Assess Pharmacokinetics of Preladenant in Participants With Chronic Hepatic Impairment (P06513)

Who this might be right for
Chronic Hepatic Impairment
Merck Sharp & Dohme LLC 42
Early research (Phase 1)Study completedNCT05935033
What this trial is testing

Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Emraclidine

Who this might be right for
Hepatic Impairment
AbbVie 38
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