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Results for “Participants With Moderate Hepatic Impairment”

94 trials

Showing 20 of 94 results

Early research (Phase 1)Study completedNCT05409911
What this trial is testing

Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants

Who this might be right for
Hepatic Impairment
Shionogi 25
Early research (Phase 1)Study completedNCT05882032
What this trial is testing

LY3502970 in Participants With Impaired and Normal Liver Function

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 29
Early research (Phase 1)Study completedNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 69
Early research (Phase 1)Study completedNCT04887064
What this trial is testing

Pharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic Impairment

Who this might be right for
Hepatic Impairment
Amgen 20
Early research (Phase 1)Study completedNCT06916078
What this trial is testing

Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function

Who this might be right for
Liver DysfunctionHealthy
Eli Lilly and Company 30
Early research (Phase 1)Ended earlyNCT05376839
What this trial is testing

Assess Safety of Cedirogant and How Cedirogant Moves Through the Body in Adult Participants With Mild, Moderate and Severe Hepatic Impairment

Who this might be right for
Hepatic Impairment
AbbVie 6
Early research (Phase 1)Study completedNCT06052566
What this trial is testing

Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014)

Who this might be right for
Non-alcoholic SteatohepatitisHepatic Impairment
Merck Sharp & Dohme LLC 22
Early research (Phase 1)Study completedNCT06529796
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Focal Segmental Glomerulosclerosis (FSGS)
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Study completedNCT05560464
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Pain
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Ended earlyNCT05126329
What this trial is testing

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 13
Early research (Phase 1)Looking for participantsNCT07165002
What this trial is testing

The Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 32
Early research (Phase 1)Study completedNCT06442436
What this trial is testing

Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Who this might be right for
Hepatic Impairment (HI)
Merck Sharp & Dohme LLC 24
Early research (Phase 1)WithdrawnNCT05490030
What this trial is testing

Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals
Early research (Phase 1)Study completedNCT07049939
What this trial is testing

Bomedemstat (MK-3543) in Participants With Mild or Moderate Hepatic Impairment (MK-3543-023)

Who this might be right for
Hepatic Insufficiency
Merck Sharp & Dohme LLC 9
Early research (Phase 1)WithdrawnNCT03277755
What this trial is testing

Investigate the Pharmacokinetics, Safety, and Tolerability of Odalasvir and AL-335 Alone and in Combination With Simeprevir in Participants With Moderately Impaired Hepatic Function

Who this might be right for
Hepatic Impairment
Janssen Research & Development, LLC
Early research (Phase 1)Study completedNCT05112419
What this trial is testing

Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment

Who this might be right for
Hepatic ImpairmentRenal Impairment
AstraZeneca 12
Early research (Phase 1)Study completedNCT06908954
What this trial is testing

The Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose

Who this might be right for
Hepatic ImpairmentHealthy
Ipsen 31
Early research (Phase 1)Study completedNCT05005312
What this trial is testing

Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332

Who this might be right for
Hepatic Impairment
Pfizer 17
Early research (Phase 1)Study completedNCT03920865
What this trial is testing

Investigate the Effect of Hepatic Impairment on the Pharmacokinetics and Safety and Tolerability of a Single Oral Dose of Risdiplam Compared to Matched Healthy Participants With Normal Hepatic Function

Who this might be right for
Muscular Atrophy, Spinal
Hoffmann-La Roche 26
Early research (Phase 1)Study completedNCT04634149
What this trial is testing

Evaluate the Drug Levels, Safety, and Tolerability of BMS-986036 in Participants With Normal Liver Function and Participants With Moderate and Severe Liver Impairment

Who this might be right for
Moderate Liver ImpairmentSevere Liver Impairment
Bristol-Myers Squibb 16
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