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Results for “Purine-Pyrimidine Metabolism”

340 trials

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Showing 20 of 340 results

Early research (Phase 1)Looking for participantsNCT06298071
What this trial is testing

A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.

Who this might be right for
Gout
Shanghai Institute Of Biological Products 36
Early research (Phase 1)Study completedNCT02336594
What this trial is testing

RDEA3170 Bioavailability Study

Who this might be right for
Gout
Ardea Biosciences, Inc. 15
Not applicableNot Yet RecruitingNCT07613164
What this trial is testing

Probiotic-Uricase Complex Preparation for Improving Uric Acid Metabolism in Patients With Hyperuricemia

Who this might be right for
Hyperuricemia, Gout
Maanshan Shiqiye Hospital 45
Large-scale testing (Phase 3)Study completedNCT04956432
What this trial is testing

A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout

Who this might be right for
Gout
Jiangsu HengRui Medicine Co., Ltd. 779
Testing effectiveness (Phase 2)Study completedNCT02498652
What this trial is testing

Phase 2a RDEA3170 and Allopurinol Combination Study in Gout Subjects

Who this might be right for
Gout
Ardea Biosciences, Inc. 41
Not applicableStudy completedNCT01830725
What this trial is testing

Purine Metabolism Enzyme SNP to Uric Acid Production

Who this might be right for
GoutHyperuricemia
Keesler Air Force Base Medical Center 100
Large-scale testing (Phase 3)Study completedNCT04052932
What this trial is testing

Evaluating the Efficacy and Safety of SHR4640 in Subjects With Gout

Who this might be right for
Gout
Jiangsu HengRui Medicine Co., Ltd. 594
Post-approval studies (Phase 4)Study completedNCT00443092
What this trial is testing

Efficacy of Proprietary Cherry Juice Blend in Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
CherryPharm 59
Testing effectiveness (Phase 2)Study completedNCT05253833
What this trial is testing

Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout

Who this might be right for
GoutArthritis, GoutyHyperuricemia+1 more
Arthrosi Therapeutics 42
Large-scale testing (Phase 3)Study completedNCT00958438
What this trial is testing

PREventative Study Against URate-Lowering Drug-Induced Gout Exacerbations (PRE-SURGE 2)

Who this might be right for
Gout
Regeneron Pharmaceuticals 248
Early research (Phase 1)Study completedNCT03272425
What this trial is testing

Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.

Who this might be right for
Gout
Ardea Biosciences, Inc. 32
Not applicableUnknownNCT04213534
What this trial is testing

The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients：A Prospective Cohort Study

Who this might be right for
Gout
Peking University Third Hospital 60
Not applicableWithdrawnNCT04224662
What this trial is testing

A Pilot Study to Explore the Role of Gut Flora in Gout

Who this might be right for
Gout
ProgenaBiome
Post-approval studies (Phase 4)Study completedNCT01654276
What this trial is testing

Effects of Hyperuricemia Reversal on Features of the Metabolic Syndrome

Who this might be right for
Gout
University of Texas Southwestern Medical Center 24
Testing effectiveness (Phase 2)Study completedNCT02252835
What this trial is testing

Evaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients With Gout

Who this might be right for
GoutHyperuricemia
Gilead Sciences 32
Not applicableNot Yet RecruitingNCT06887452
What this trial is testing

Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With Gout

Who this might be right for
GoutGouty Arthritis
VA Office of Research and Development 310
Early research (Phase 1)Study completedNCT02608710
What this trial is testing

RDEA3170 PK/PD Study

Who this might be right for
Gout
Ardea Biosciences, Inc. 40
Testing effectiveness (Phase 2)UnknownNCT06270225
What this trial is testing

SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.

Who this might be right for
Gout Arthritis
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 157
Testing effectiveness (Phase 2)Study completedNCT03002974
What this trial is testing

Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty Arthritis

Who this might be right for
Acute Gouty Arthritis
Swedish Orphan Biovitrum 165
Large-scale testing (Phase 3)Ended earlyNCT01459796
What this trial is testing

Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares

Who this might be right for
Gout
Regeneron Pharmaceuticals 220
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