Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Severe Heart Valve Disease”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Not applicableNot Yet RecruitingNCT07751965
What this trial is testing

Prospective Multicenter Study Evaluating Myval TAVR Safety and Effectiveness in High-risk Severe AR

Who this might be right for
Aortic RegurgitationAortic DiseaseCalcified Aortic Valve
Ceric Sàrl 164
Not applicableNot Yet RecruitingNCT06721676
What this trial is testing

Study of Transcatheter Aortic Valve Replacement With A² Flex and Commissural Alignment Technology in Severe Aortic Stenosis

Who this might be right for
Aortic Stenosis Symptomatic
Peijia Medical Technology (Suzhou) Co., Ltd. 10
Not applicableActive Not RecruitingNCT03517436
What this trial is testing

ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis

Who this might be right for
Aortic Valve Stenosis
Edwards Lifesciences 101
Not applicableStudy completedNCT04665596
What this trial is testing

Valvosoft First-In-Human Study in Severe Symptomatic Aortic Stenosis

Who this might be right for
Aortic Valve Stenosis
Cardiawave SA 10
Not applicableNot Yet RecruitingNCT05528211
What this trial is testing

Safety and Efficacy of Emergent TAVI in Patients With Severe AS

Who this might be right for
Aortic Valve StenosisTranscatheter Aortic Valve ImplantationEmergencies
Qilu Hospital of Shandong University 10
Post-approval studies (Phase 4)Not Yet RecruitingNCT07735130
What this trial is testing

Angiotensin Receptor Blocker After TAVR in Severe Aortic Stenosis With Left Ventricular Hypertrophy (ARBITAR)

Who this might be right for
Transcatheter Aortic Valve Replacement (TAVR)Left Ventricular HypertrophySevere Aortic Stenosis
Seoul National University Hospital 632
Not applicableUnknownNCT04230551
What this trial is testing

Reverse Remodeling After PTSMA in Severe But Asymptomatic LVOT Obstruction

Who this might be right for
HOCM, Hypertrophic Obstructive CardiomyopathyLVOTO - Left Ventricular Outflow Tract ObstructionRemodeling, Ventricular
St. Antonius Hospital 15
Not applicableStudy completedNCT04571372
What this trial is testing

Prognostic Value of Soluble Urokinase-type Plasminogen Activator Receptor in Valvular Heart Disease

Who this might be right for
Severe Aortic Stenosis or Severe Aortic Regurgitation
Yonsei University 222
Not applicableActive Not RecruitingNCT02732704
What this trial is testing

THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

Who this might be right for
Aortic Regurgitation
JenaValve Technology, Inc. 100
Not applicableStudy completedNCT04002648
What this trial is testing

Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results?

Who this might be right for
Barlow's DiseaseProlapse; Mitral
Ospedale San Raffaele 208
Not applicableLooking for participantsNCT03003299
What this trial is testing

PARTNER 3 Trial - Aortic Valve-in-Valve

Who this might be right for
Aortic StenosisAortic Stenosis, Severe
Edwards Lifesciences 125
Not applicableStudy completedNCT02841917
What this trial is testing

Reactive Oxygen Species Following Aortic Valve Replacement

Who this might be right for
Aortic Stenosis
University Hospital Southampton NHS Foundation Trust 3
Not applicableLooking for participantsNCT06906926
What this trial is testing

Harmony TPV EMEA PMS

Who this might be right for
Severe Pulmonary Valve Regurgitation
Medtronic Cardiovascular 80
Not applicableStudy completedNCT01675440
What this trial is testing

Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Extreme Risk Subjects Who Need Aortic Valve Replacement

Who this might be right for
Severe Aortic Stenosis
Medtronic Cardiovascular 782
Not applicableStudy completedNCT01074658
What this trial is testing

CoreValve Advance International Post Market Study

Who this might be right for
Severe Aortic Stenosis
Medtronic Cardiac Rhythm and Heart Failure 1,015
Not applicableActive Not RecruitingNCT04788888
What this trial is testing

Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation

Who this might be right for
Symptomatic Severe Aortic Stenosis
Abbott Medical Devices 434
Not applicableStudy completedNCT02370511
What this trial is testing

Mitral Implantation of TRAnscatheter vaLves

Who this might be right for
Mitral Valve Disease
Mayra Guerrero 91
Not applicableStudy completedNCT05478161
What this trial is testing

Investigation of the ALLEGRA THV System With a New Delivery System in Patients With Aortic Stenosis or Failed Surgical Bioprosthesis

Who this might be right for
Transcatheter Aortic Valve Implantation
NVT GmbH 137
Not applicableLooking for participantsNCT06168370
What this trial is testing

Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation

Who this might be right for
Severe Aortic Valve Stenosis
St. Antonius Hospital 2,500
Not applicableNot Yet RecruitingNCT06902922
What this trial is testing

Impact of Severe Tricuspid Regurgitation Correction on Gut Microbiota and Gastrointestinal Function

Who this might be right for
Tricuspid Regurgitation (TR)
Francesco Maisano 150
Next Page