Testing effectiveness (Phase 2)Study completedNCT02640807What this trial is testingIL-7 to Restore Absolute Lymphocyte Counts in Sepsis PatientsWho this might be right forSevere Sepsis With Septic Shock Revimmune 27
Not applicableStudy completedNCT02030158What this trial is testingStatistical Analysis Plan for an Individual Patient Data Meta-analysis of Three, International Trials Comparing Protocolised With Usual Resuscitation in Patients Presenting to the Emergency Department With Severe Sepsis and Septic ShockWho this might be right forSevere Sepsis and Septic Shock Australian and New Zealand Intensive Care Research Centre 4,210
Not applicableUnknownNCT02887274What this trial is testingApplication of Stimulated Immune Response Change to Predict Outcome of Patient With Severe SepsisWho this might be right forSystemic Inflammatory Response Syndrome (SIRS)SepsisSevere Sepsis+2 more Chang Gung Memorial Hospital 300
Large-scale testing (Phase 3)UnknownNCT02654561What this trial is testingEfficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular CoagulationWho this might be right forSepsisDisseminated Intravascular Coagulation China Medical University, China 600
Early research (Phase 1)Study completedNCT02960854What this trial is testingNivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock.Who this might be right forSevere Sepsis Bristol-Myers Squibb 38
Not applicableStudy completedNCT01988428What this trial is testingPrehospital Antibiotics Against Sepsis TrialWho this might be right forSepsisSevere SepsisSeptic Shock Amsterdam UMC, location VUmc 2,672
Post-approval studies (Phase 4)Ended earlyNCT02109965What this trial is testingThe Effect of Dexmedetomidine on Microcirculation in Severe SepsisWho this might be right forSevere Sepsis National Taiwan University Hospital 12
Testing effectiveness (Phase 2)Study completedNCT06072222What this trial is testingEffect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged VentilationWho this might be right forARDSSeptic Shock King Abdul Aziz Specialist Hospital 200
Not applicableStudy completedNCT02159079What this trial is testingControlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study)Who this might be right forSepsis Vanderbilt University 30
Not applicableUnknownNCT01486524What this trial is testingPharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe SepsisWho this might be right forSevere SepsisSeptic Shock Sirius Genomics Inc. 3,000
Not applicableStudy completedNCT02346331What this trial is testingEpidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western KenyaWho this might be right forSepsisSevere SepsisSeptic Shock Duke University 198
Testing effectiveness (Phase 2)Ended earlyNCT02797431What this trial is testingImmune Reconstitution of Immunosuppressed Sepsis PatientsWho this might be right forSevere Sepsis With Septic Shock University Hospital, Limoges 16
Testing effectiveness (Phase 2)Study completedNCT03592277What this trial is testingVitamin C & Thiamine to Treat Sepsis and Septic ShockWho this might be right forSepsisSeptic Shock Trinity Health Of New England 120
Large-scale testing (Phase 3)UnknownNCT01858909What this trial is testingEfficacy of Melatonin in Patients With Severe Sepsis or Septic ShockWho this might be right forSevere SepsisSeptic Shock Aragon Institute of Health Sciences 110
Not applicableUnknownNCT00335907What this trial is testingProtocol-driven Hemodynamic Support for Patients With Septic ShockWho this might be right forShock, SepticSevere SepsisSepsis National Institute of General Medical Sciences (NIGMS) 70
Large-scale testing (Phase 3)Study completedNCT00135473What this trial is testingEfficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)Who this might be right forSevere SepsisSeptic Shock SepNet - Critical Care Trials Group 600
Post-approval studies (Phase 4)Ended earlyNCT03335124What this trial is testingThe Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic ShockWho this might be right forSepsisSeptic ShockCritical Illness+1 more University Medical Centre Ljubljana 5
Post-approval studies (Phase 4)Study completedNCT02365272What this trial is testingPharmacokinetic/Pharmacodynamic Evaluation Amikacin in Critically Ill Patients Admitted at the Emergency DepartmentWho this might be right forSepsis Universitaire Ziekenhuizen KU Leuven 100
Testing effectiveness (Phase 2)Study completedNCT01352182What this trial is testingPharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic ShockWho this might be right forSevere SepsisSeptic Shock Children's Hospital Medical Center, Cincinnati 12
Large-scale testing (Phase 3)Ended earlyNCT01315496What this trial is testingGCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic ShockWho this might be right forSevere SepsisSeptic Shock Green Cross Corporation 214