Not applicableActive Not RecruitingNCT02306993What this trial is testingSickle Cell Hemoglobinopathies and Bone HealthWho this might be right forSickle Cell DiseaseSickle Cell Trait UConn Health 45
Not applicableStudy completedNCT01633021What this trial is testingDeveloping the Family Map: Looking at Communal CopingWho this might be right forSickle CellDiabetesCancer+2 more National Human Genome Research Institute (NHGRI) 1,061
Early research (Phase 1)Study completedNCT05036512What this trial is testingEvaluate GBT021601 in Single and Multiple Doses in Healthy ParticipantsWho this might be right forSickle Cell Disease Pfizer 129
Not applicableLooking for participantsNCT06301893What this trial is testingUganda Sickle Surveillance Study (US-3)Who this might be right forSickle Cell Disease Children's Hospital Medical Center, Cincinnati 1,000,000
Testing effectiveness (Phase 2)Ended earlyNCT06078696What this trial is testingSiplizumab for Sickle Cell Disease TransplantWho this might be right forAnemia, Sickle Cell Columbia University 1
Not applicableLooking for participantsNCT03685721What this trial is testingGenotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell DiseaseWho this might be right forSickle CellPKLR VariantsAdenosine Triphosphate Activities National Heart, Lung, and Blood Institute (NHLBI) 800
Early research (Phase 1)Study completedNCT04983264What this trial is testingEvaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD)Who this might be right forSickle Cell Disease Pfizer 6
Large-scale testing (Phase 3)Active Not RecruitingNCT03814746What this trial is testingStudy of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 255
Not applicableActive Not RecruitingNCT05292781What this trial is testingCHOICES3: Sickle Cell Disease Parenting CHOICESWho this might be right forSickle Cell DiseaseSickle Cell Trait University of Florida 506
Not applicableStudy completedNCT05407805What this trial is testingLearn About Sickle Cell Disease In Adult PatientsWho this might be right forSickle Cell Disease Pfizer 98
Post-approval studies (Phase 4)Study completedNCT04662931What this trial is testingAn Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 140
Not applicableStudy completedNCT02561312What this trial is testingComparison of Two Methods of Transfusion for Stroke Prevention in Sickle CellWho this might be right forAnemia, Sickle CellSickling Disorder Due to Hemoglobin S Chattanooga-Hamilton County Hospital Authority 9
Early research (Phase 1)Study completedNCT03126695What this trial is testingCompare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are AdministeredWho this might be right forSickle Cell Disease AstraZeneca 44
Not applicableStudy completedNCT02571088What this trial is testingEvaluation of a Training Program for Homozygous Sickle Cell Disease PatientsWho this might be right forSickle Cell Hemoglobin C DiseaseHemoglobin S Disease Centre Hospitalier Universitaire de Saint Etienne 40
Early research (Phase 1)UnknownNCT00599482What this trial is testingFar Infrared Radiation for Sickle Cell Pain ManagementWho this might be right forAnemia, Sickle Cell GAAD Medical Research Institute Inc. 10
Large-scale testing (Phase 3)Study completedNCT00005782What this trial is testingMobilization and Handling of Stem Cells for Transplant From Healthy Volunteers With Sickle Cell TraitWho this might be right forSickle Cell Trait National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 12
Not applicableLooking for participantsNCT06071377What this trial is testingAchieving Understanding of the Natural History of Sickle Cell Trait (AUNT)Who this might be right forSickle Cell Trait National Alliance for Sickle Cell Centers 1,000
Not applicableStudy completedNCT04273022What this trial is testingEffect of Exercise on Biomarkers in SCTWho this might be right forSickle Cell Trait St. Louis University 12
Early research (Phase 1)Ended earlyNCT05878704What this trial is testingStudy of GBT021601 in Participants With Renal ImpairmentWho this might be right forRenal Impairment Pfizer 8
Early research (Phase 1)Looking for participantsNCT07015684What this trial is testing131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)Who this might be right forSickling Disorder Due to Hemoglobin S Columbia University 24