Not applicableNot Yet RecruitingNCT06901596What this trial is testingSugammadex Reduces Antiemetic Effect of DexamethasoneWho this might be right forPONV Augusta University 100
Not applicableUnknownNCT04165057What this trial is testingEfficacy and Safety of Optimal Muscle Tension Management During Laparoscopic CholecystectomyWho this might be right forAnesthesia National Taiwan University Hospital Hsin-Chu Branch 70
Not applicableStudy completedNCT01006720What this trial is testingSugammadex and Neostigmine at Residual Neuromuscular BlockadeWho this might be right forResidual Neuromuscular Block (TOF-ratio of 0.2) Technical University of Munich 99
Large-scale testing (Phase 3)Study completedNCT00826176What this trial is testingEfficacy and Safety of 4.0 mg/kg Sugammadex at 1-2 PTC in Chinese and European Subjects (Study 19.4.335)(P05775AM1)(COMPLETED)Who this might be right forAnesthesia, GeneralNeuromuscular Blockade Merck Sharp & Dohme LLC 164
Post-approval studies (Phase 4)Study completedNCT03322657What this trial is testingSugammadex Versus Neostigmine for Reversal of Rocuronium NeuromuscularWho this might be right forNeuromuscular BlockadeAnesthesia The Cleveland Clinic 69
Not applicableUnknownNCT06432621What this trial is testingRole of Sugammadex and Neostigmine for Recovery From RocuroniumWho this might be right forAnesthesia Ain Shams University 60
Large-scale testing (Phase 3)Study completedNCT00473694What this trial is testingComparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025)Who this might be right forAnesthesia, General Merck Sharp & Dohme LLC 182
Post-approval studies (Phase 4)Study completedNCT02414880What this trial is testingSugammadex Versus Neostigmine in Patients With Liver Cirrhosis Undergoing Liver ResectionWho this might be right forCirrhosis and Chronic Liver Disease Cairo University 60
Post-approval studies (Phase 4)Ended earlyNCT02256280What this trial is testingDouble Blind Controlled Trial Comparing Sugammadex and Neostigmine After Thoracic AnesthesiaWho this might be right forNeuromuscular Blockade Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 70
Testing effectiveness (Phase 2)Study completedNCT00591786What this trial is testingA Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Japanese Participants. Part A (P05957)Who this might be right forAnesthesia, General Merck Sharp & Dohme LLC 100
Post-approval studies (Phase 4)Study completedNCT03346070What this trial is testingEfficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)Who this might be right forNeuromuscular Blockade Merck Sharp & Dohme LLC 207
Post-approval studies (Phase 4)Study completedNCT01972659What this trial is testingEffects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology PatientsWho this might be right forPre-eclampsia Aggravated Kocaeli University 80
Not applicableStudy completedNCT03576118What this trial is testingModerate vs Deep Neuromuscular Block on Biotrauma During LaparoscopyWho this might be right forPneumoperitoneum Ajou University School of Medicine 74
Early research (Phase 1)Study completedNCT02011490What this trial is testingPharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105)Who this might be right forRenal InsufficiencyRenal Impairment Merck Sharp & Dohme LLC 33
Post-approval studies (Phase 4)Study completedNCT03351608What this trial is testingEfficacy, Safety, and Pharmacokinetics of Sugammadex for Reversal of Neuromuscular Blockade (NMB) in Pediatric Participants (MK-8616-089)Who this might be right forNeuromuscular Blockade Merck Sharp & Dohme LLC 288
Large-scale testing (Phase 3)Study completedNCT01509651What this trial is testingSugammadex and Heart FailureWho this might be right forPostoperative Neuromuscular Block Onze Lieve Vrouw Hospital 12
Post-approval studies (Phase 4)Study completedNCT02861131What this trial is testingThe Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary ComplicationsWho this might be right forPostoperative ComplicationsNeuromuscular Blockade Oregon Health and Science University 200
Not applicableStudy completedNCT05992090What this trial is testingNeuromuscular Blockade Monitoring Using Kine-myography vs Electromyography.Who this might be right forNeuromuscular BlockadeResidual Neuromuscular Blockade Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. 129
Post-approval studies (Phase 4)WithdrawnNCT02410590What this trial is testingRocuronium + Sugammadex vs. Succinylcholine + Cisatracurium + Neostigmine/Atropine in Obese Participants (MK-8616-104)Who this might be right forNeuromuscular Blockade Merck Sharp & Dohme LLC
Post-approval studies (Phase 4)UnknownNCT01424488What this trial is testingSugammadex Efficacy and Safety for Reversal of Pipecuronium-induced Neuromuscular BlockadeWho this might be right forAdult Subjects Undergoing Abdominal Surgery Under General Anesthesia Central Clinical Hospital #1 of LLC Russian Railways 42