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Results for “Treatment Resistant Major Depression”

377 trials

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Showing 20 of 377 results

Testing effectiveness (Phase 2)Looking for participantsNCT06524830
What this trial is testing

Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

Who this might be right for
Treatment Resistant Depression
atai Therapeutics, Inc. 142
Post-approval studies (Phase 4)Study completedNCT04727229
What this trial is testing

Stellate Ganglion Block for Major Depressive Disorder.

Who this might be right for
Treatment Resistant DepressionMajor Depressive Disorder
Unity Health Toronto 10
Large-scale testing (Phase 3)WithdrawnNCT04924257
What this trial is testing

ECT vs. Esketamine

Who this might be right for
Treatment Resistant DepressionMajor Depressive Disorder
Medical University Innsbruck
Large-scale testing (Phase 3)Study completedNCT00789854
What this trial is testing

Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients

Who this might be right for
Major Depressive DisorderTreatment Resistant Depression
AstraZeneca 688
Large-scale testing (Phase 3)Looking for participantsNCT07088380
What this trial is testing

Ketamine Augmentation of ECT in Treatment-Resistant Depression

Who this might be right for
Major Depressive DisorderTreatment Resistant Depression
Università Vita-Salute San Raffaele 30
Very early researchStudy completedNCT04977674
What this trial is testing

Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine

Who this might be right for
Depressive Disorder, Treatment-Resistant
King's College London 27
Not applicableStudy completedNCT02752178
What this trial is testing

Peripheral Immunomarker Validation in Treatment-resistant Depression

Who this might be right for
Depressive Disorder, Major
University of Cambridge 393
Not applicableStudy completedNCT07097025
What this trial is testing

2-Year Study of Vagus Nerve Stimulation for Higher-Grade Treatment-Resistant Depression: Clinical Outcomes and Policy Recommendation

Who this might be right for
Treatment Resistant Depression (TRD)Depression - Major Depressive DisorderBipolar Depression
Dr.Yoav Domany 19
Not applicableNot Yet RecruitingNCT07783906
What this trial is testing

Precision Closed-loop Brain-Computer Interface Neuromodulation for Treatment-Resistant Depression

Who this might be right for
Treatment-Resistant Major Depressive DisorderMajor Depressive Disorder
Shanghai Mental Health Center 70
Testing effectiveness (Phase 2)Study completedNCT01204918
What this trial is testing

Efficacy and Tolerability of Riluzole in Treatment Resistant Depression

Who this might be right for
Depression
Yale University 104
Early research (Phase 1)Not Yet RecruitingNCT07307768
What this trial is testing

Ketamine Biomarker Validation

Who this might be right for
Treatment Resistant Depression (TRD)
Soterix Medical 20
Testing effectiveness (Phase 2)Looking for participantsNCT06511908
What this trial is testing

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

Who this might be right for
SuicideDepressive Disorder, Treatment-ResistantKetamine+10 more
National Institute of Mental Health (NIMH) 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07810738
What this trial is testing

The BAARD Study : Evaluating a Computerized Approach to Treatment Selection in Older Adults With Treatment Resistant Depression.

Who this might be right for
Late Life Treatment Resistant DepressionDepression - Major Depressive DisorderTreatment Resistant Depression
Washington University School of Medicine 300
Early research (Phase 1)Looking for participantsNCT02994433
What this trial is testing

NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits

Who this might be right for
Depressive Disorder, MajorDepressive Disorder, Treatment-Resistant
Washington University School of Medicine 60
Testing effectiveness (Phase 2)Study completedNCT04979910
What this trial is testing

Targeting IL-17A for Treatment-Resistant Depression

Who this might be right for
Major Depressive Disorder
Icahn School of Medicine at Mount Sinai 7
Large-scale testing (Phase 3)Looking for participantsNCT07623135
What this trial is testing

Lumateperone for Late-Life Depression

Who this might be right for
Treatment Resistant Depression (TRD)Late Life Depression (LLD)Depression / Major Depressive Disorder
Eric Lenze 100
Not applicableTemporarily pausedNCT06112652
What this trial is testing

Neuromodulation of Different Doses to Treat TRD Guided by pBFS Technique

Who this might be right for
Moderate DepressionMajor Depressive DisorderSevere Depression
Changping Laboratory 100
Testing effectiveness (Phase 2)Study completedNCT03870776
What this trial is testing

RESIST : Administration of MAP4343 in Antidepressant Non-Responders Patients Experiencing a Major Depressive Episode

Who this might be right for
Depression
Mapreg 126
Not applicableStudy completedNCT06232291
What this trial is testing

Observation of Safety and Tolerability Within 1 Year of the Use of R-ketamine / Placebo in Drug-resistant Depression

Who this might be right for
Treatment-Resistant DepressionMajor Depressive Disorder
Medical University of Gdansk 3
Post-approval studies (Phase 4)Study completedNCT05045378
What this trial is testing

Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression

Who this might be right for
Treatment-resistant DepressionMajor Depressive Disorder
Taipei Veterans General Hospital, Taiwan 12
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