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Results for “WHIM”

79 trials

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Showing 20 of 79 results

Early research (Phase 1)Ended earlyNCT03277209
What this trial is testing

To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas

Who this might be right for
Pancreas Cancer
Weill Medical College of Cornell University 2
Early research (Phase 1)Study completedNCT01120457
What this trial is testing

First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers

Who this might be right for
Acute Myelogenous LeukemiaDiffuse Large B-Cell LeukemiaChronic Lymphocytic Leukemia+1 more
Bristol-Myers Squibb 96
Not applicableLooking for participantsNCT06962163
What this trial is testing

Assessement of Potential Interest of [68Ga]Ga-PentixaFor PET/CT in Metastatic Triple Negative Breast Cancer Patients

Who this might be right for
Metastatic Breast Cancer
Institut Cancerologie de l'Ouest 12
Early research (Phase 1)Ended earlyNCT01374503
What this trial is testing

First in Man Study of ALX-0651, a Nanobody Inhibiting CXCR4

Who this might be right for
Healthy Volunteers
Ablynx, a Sanofi company 52
Early research (Phase 1)Study completedNCT06547112
What this trial is testing

A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization

Who this might be right for
Multiple Myeloma
Washington University School of Medicine 20
Not applicableStudy completedNCT07212959
What this trial is testing

As Part of a Pilot Study, Visualization of Inflammatory Activity in Systemic Sclerosis Using CXCR4 PET/CT

Who this might be right for
Systemic Sclerosis (SSc)
Wuerzburg University Hospital 12
Testing effectiveness (Phase 2)WithdrawnNCT02115672
What this trial is testing

Imatinib and BL-8040 (Novel Anti CXCR4 Antagonist) for Improving Molecular Response in Chronic Myelogenous Leukemia

Who this might be right for
Chronic Myeloid Leukemia
Sheba Medical Center
Not applicableStudy completedNCT01295242
What this trial is testing

Natural History of Human Papillomavirus (HPV) Infections in Mid-Adult Women (WHIM)

Who this might be right for
Papillomavirus Infections
University of Washington 409
Not applicableLooking for participantsNCT05519735
What this trial is testing

Lymphatic Organs and Myocardium After Myocardial Infarction

Who this might be right for
Myocardial InfarctionMyocardial InjuryMyocardial Inflammation
Wuerzburg University Hospital 57
Large-scale testing (Phase 3)WithdrawnNCT00243568
What this trial is testing

Vicriviroc, a CCR5 Inhibitor, Added to an Optimized Antiretroviral Therapy for Previously Treated HIV (VICTOR-E2) (Study P04285

Who this might be right for
HIV InfectionsAcquired Immunodeficiency Syndrome
Merck Sharp & Dohme LLC
Testing effectiveness (Phase 2)Ended earlyNCT02765165
What this trial is testing

Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)

Who this might be right for
Solid Tumors (Phase 1)Relapsed/Recurrent GBM (Phase 2)
Proximagen, LLC 26
Very early researchUnknownNCT06086327
What this trial is testing

Application of 68Ga-Pentixafor PET/CT for Thymoma

Who this might be right for
Thymoma
Peking Union Medical College Hospital 100
Early research (Phase 1)Not Yet RecruitingNCT06981806
What this trial is testing

Phase I Study of Cosibelimab and Balixafortide in Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Metastatic Pancreatic Ductal Adenocarcinoma
Arsen Osipov 24
Early research (Phase 1)Study completedNCT02179970
What this trial is testing

To Assess the Safety of Continuous IV Administration of Plerixafor in Patients With Advanced Pancreatic, Ovarian and Colorectal Cancers

Who this might be right for
Pancreatic Adenocarcinoma MetastaticOvarian Serous AdenocarcinomaColorectal Cancer Metastatic
CCTU- Cancer Theme 26
Testing effectiveness (Phase 2)Study completedNCT00089466
What this trial is testing

Safety and Activity of the Oral HIV Entry Inhibitor AMD11070 in HIV Infected Patients

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 6
Early research (Phase 1)Study completedNCT01841476
What this trial is testing

Safety and Efficacy of POL6326 for Mobilization of Hematopoietic Stem Cells in Healthy Volunteers

Who this might be right for
Healthy
Polyphor Ltd. 27
Very early researchUnknownNCT04504526
What this trial is testing

Value of Chemokine Receptor CXCR4 Imaging for Diagnosis and Prognostic Evaluation in Lymphoproliferative Diseases

Who this might be right for
LymphomaMultiple MyelomaLeukemia
First Affiliated Hospital of Fujian Medical University 50
Large-scale testing (Phase 3)Study completedNCT02231879
What this trial is testing

Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome

Who this might be right for
MyelokathexisInfectionsNeutropenia+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 20
Very early researchStudy completedNCT03020524
What this trial is testing

Autologous CD4 T-Cells in HIV (C34-CXCR4)

Who this might be right for
Hiv
University of Pennsylvania 9
Not applicableUnknownNCT00302562
What this trial is testing

The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

Who this might be right for
Laryngeal CancerHypopharyngeal Cancer
National Taiwan University Hospital 100
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