Testing effectiveness (Phase 2)Study completedNCT02283762What this trial is testingEfficacy and Safety of Riociguat in Patients With Systemic SclerosisWho this might be right forScleroderma, Systemic Bayer 121
Testing effectiveness (Phase 2)Looking for participantsNCT07287670What this trial is testingEncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)Who this might be right forDiffuse Cutaneous Systemic Sclerosis Mediar Therapeutics 85
Testing effectiveness (Phase 2)Study completedNCT01895244What this trial is testingAutologous Stem Cell Transplantation for Progressive Systemic SclerosisWho this might be right forSclerodermaCardiac InvolvementAutologous Stem Cell Transplantation University Hospital Tuebingen 44
Testing effectiveness (Phase 2)Looking for participantsNCT06375005What this trial is testingEfficacy and Safety of Telitacicept in the Treatment of Systemic SclerosisWho this might be right forDiffuse Cutaneous Systemic Sclerosis Second Affiliated Hospital, Zhejiang University, School of Medicine 38
Testing effectiveness (Phase 2)WithdrawnNCT05098145What this trial is testingA Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic SclerosisWho this might be right forDiffuse Cutaneous Systemic Sclerosis Talaris Therapeutics Inc.
Testing effectiveness (Phase 2)WithdrawnNCT04138485What this trial is testingEfficacy and Safety of IgPro10 in Adults With Systemic Sclerosis (SSc)Who this might be right forDiffuse Cutaneous Systemic Sclerosis CSL Behring
Large-scale testing (Phase 3)UnknownNCT00428883What this trial is testingHigh Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic SclerosisWho this might be right forScleroderma, Diffuse Università Politecnica delle Marche 45
Testing effectiveness (Phase 2)Looking for participantsNCT07047690What this trial is testingNemolizumab for the Treatment of Adults With Systemic SclerosisWho this might be right forSystemic Sclerosis Galderma R&D 162
Not applicableNot Yet RecruitingNCT07642297What this trial is testingTL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP)Who this might be right forSystemic Sclerosis (SSc)Diffuse Cutaneous Systemic SclerosisSkin Fibrosis Fondazione Policlinico Universitario Campus Bio-Medico 20
Testing effectiveness (Phase 2)Looking for participantsNCT03630211What this trial is testingAutologous Stem Cell Transplantation in Patients With Systemic SclerosisWho this might be right forSystemic SclerosisDiffuse Sclerosis SystemicInterstitial Lung Disease+1 more Paul Szabolcs 8
Testing effectiveness (Phase 2)Study completedNCT03274076What this trial is testingEvaluation of Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis (dcSSc)Who this might be right forSystemic SclerosisScleroderma University of Michigan 15
Testing effectiveness (Phase 2)Study completedNCT00043706What this trial is testingSafety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic SclerosisWho this might be right forSystemic SclerosisScleroderma Genzyme, a Sanofi Company
Not applicableNot Yet RecruitingNCT07605637What this trial is testingEarly Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Effectiveness of STR-P005Who this might be right forRelapsed/Refractory Autoimmune Diseases Beijing GoBroad Hospital 18
Early research (Phase 1)Active Not RecruitingNCT06255028What this trial is testingCNTY-101 in Participants With Refractory B Cell-mediated Autoimmune DiseasesWho this might be right forSystemic Lupus ErythematosusLupus NephritisIdiopathic Inflammatory Myopathies+1 more Century Therapeutics, Inc. 6
Testing effectiveness (Phase 2)WithdrawnNCT02588625What this trial is testingA Double-Blinded Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986020 Versus Placebo in Diffuse Cutaneous Systemic Sclerosis (dcSSc)Who this might be right forScleroderma Bristol-Myers Squibb
Testing effectiveness (Phase 2)Study completedNCT01670565What this trial is testingBelimumab for the Treatment of Diffuse Cutaneous Systemic SclerosisWho this might be right forSystemic Sclerosis Hospital for Special Surgery, New York 20
Not applicableUnknownNCT01785056What this trial is testingIVIG Treatment in Systemic SclerosisWho this might be right forSystemic SclerosisDiffuse Scleroderma Georgetown University 14
Testing effectiveness (Phase 2)Ended earlyNCT04680975What this trial is testingEfficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic SclerosisWho this might be right forDiffuse Cutaneous Systemic Sclerosis Kadmon, a Sanofi Company 10
Testing effectiveness (Phase 2)Study completedNCT05559580What this trial is testingA Study in People With Systemic Sclerosis to Test Whether Avenciguat (BI 685509) Has an Effect on Lung Function and Other Systemic Sclerosis SymptomsWho this might be right forScleroderma, Systemic Boehringer Ingelheim 214
Testing effectiveness (Phase 2)Looking for participantsNCT07473154What this trial is testingControlling Hyperactive Immunity With Long-lived LymphocytesWho this might be right forDiffuse Cutaneous Systemic SclerosisRheumatoid Arthritis (RA)Systemic Sclerosis (SSc)+1 more Quell Therapeutics Limited 16