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Results for “mTOR”

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Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT00918333
What this trial is testing

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

Who this might be right for
Adult Nasal Type Extranodal NK/T-cell LymphomaAnaplastic Large Cell LymphomaAngioimmunoblastic T-cell Lymphoma+25 more
Mayo Clinic 124
Early research (Phase 1)Study completedNCT00962507
What this trial is testing

Panobinostat and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

Who this might be right for
LymphomaMultiple Myeloma and Plasma Cell Neoplasm
City of Hope Medical Center 11
Not applicableLooking for participantsNCT05233722
What this trial is testing

MTOR as Mediator of Insulin Sensitivity Study

Who this might be right for
Insulin Sensitivity
University of Copenhagen 10
Not applicableActive Not RecruitingNCT05470218
What this trial is testing

Leucine, mTOR and Athero

Who this might be right for
Atherosclerosis
University of Missouri-Columbia 10
Early research (Phase 1)Study completedNCT01899053
What this trial is testing

A Safety and Pharmacokinetic Study of TAK-228 in Combination With TAK-117 in Adult Participants With Advanced Nonhematologic Malignancies

Who this might be right for
Advanced Nonhematologic Malignancies
Millennium Pharmaceuticals, Inc. 101
Not applicableStudy completedNCT07562672
What this trial is testing

Tongyangxiao Lotion for Postoperative Wound Healing After Anal Fistula Surgery

Who this might be right for
Postoperative Wound Healing in Anal Fistula Surgery
Yongkang An 115
Large-scale testing (Phase 3)Active Not RecruitingNCT04582136
What this trial is testing

Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
Chinese SLE Treatment And Research Group 146
Testing effectiveness (Phase 2)Active Not RecruitingNCT06385496
What this trial is testing

Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With mTOR Genetic Changes (MATCH - Subprotocol L)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmRefractory Lymphoma+2 more
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Ended earlyNCT02438761
What this trial is testing

PF-05212384 (PKI-587) for t-AML/MDS or de Novo Relapsed or Refractory Acute Myeloid Leukemia (AML) (LAM-PIK)

Who this might be right for
Therapy-related Acute Myeloid Leukemia and Myelodysplastic SyndromeAcute Myeloid Leukemia, in Relapsede Novo Acute Myeloid Leukemia at Diagnostic
Institut Curie 10
Large-scale testing (Phase 3)Study completedNCT01223027
What this trial is testing

Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma

Who this might be right for
Metastatic Renal Cell Carcinoma
Novartis Pharmaceuticals 564
Testing effectiveness (Phase 2)Study completedNCT00634270
What this trial is testing

A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1
University of Alabama at Birmingham 58
Testing effectiveness (Phase 2)Ended earlyNCT01495247
What this trial is testing

Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Inoperable Locally Advanced Breast CancerMetastatic Breast Cancer (MBC)
Novartis Pharmaceuticals 18
Testing effectiveness (Phase 2)Study completedNCT01684449
What this trial is testing

Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma

Who this might be right for
Advanced Soft Tissue Sarcoma
Grupo Espanol de Investigacion en Sarcomas 28
Testing effectiveness (Phase 2)Study completedNCT02711826
What this trial is testing

Treg Therapy in Subclinical Inflammation in Kidney Transplantation

Who this might be right for
Kidney TransplantAdult Living Donor Kidney Transplant RecipientsRenal Transplant+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 32
Early research (Phase 1)Study completedNCT02238496
What this trial is testing

Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas

Who this might be right for
Brain Tumor, RecurrentGlioblastomaAnaplastic Astrocytoma+2 more
Andrew B Lassman, MD 10
Not applicableStudy completedNCT01847261
What this trial is testing

Effects of Protein Blends on Muscle Protein Synthesis in Healthy Older Adults

Who this might be right for
Muscle Synthesis
DuPont Nutrition and Health 20
Early research (Phase 1)Temporarily pausedNCT03065062
What this trial is testing

Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors

Who this might be right for
Lung Cancer Squamous CellSolid TumorsHead & Neck Cancer+1 more
Dana-Farber Cancer Institute 75
Very early researchStudy completedNCT01513356
What this trial is testing

Pharmacodynamic Study of BKM120 in Breast Cancer

Who this might be right for
Breast Cancer
Sofia Perea, Director Clinical Trials Unit. 20
Early research (Phase 1)Study completedNCT01473095
What this trial is testing

Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma

Who this might be right for
Solid TumorMalignant LymphomaTumor
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 120
Testing effectiveness (Phase 2)Study completedNCT01026792
What this trial is testing

Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery

Who this might be right for
Cervical AdenocarcinomaCervical Adenosquamous CarcinomaCervical Squamous Cell Carcinoma+5 more
National Cancer Institute (NCI) 38
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