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Results for “Ammonia Metabolism”

24 trials

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Showing 20 of 24 results

Not applicableStudy completedNCT05376488
What this trial is testing

Effect of Brief Dietary Intervention on Ammonia Levels

Who this might be right for
CirrhosisHepatic Encephalopathy
Hunter Holmes Mcguire Veteran Affairs Medical Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06255782
What this trial is testing

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseOrnithine Carbamoyltransferase Deficiency (Disorder)+1 more
iECURE, Inc. 20
Not applicableStudy completedNCT00312910
What this trial is testing

Probiotics for the Prevention of Major Complications of Cirrhosis

Who this might be right for
Liver Cirrhosis
Meir Medical Center 50
Not applicableUnknownNCT05421351
What this trial is testing

Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLF

Who this might be right for
Hepatic EncephalopathyAcute-On-Chronic Liver FailureDecompensated Cirrhosis
Post Graduate Institute of Medical Education and Research, Chandigarh 135
Not applicableStudy completedNCT01151475
What this trial is testing

Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE)

Who this might be right for
Liver CirrhosisHepatic Encephalopathy
University of Aarhus 10
Testing effectiveness (Phase 2)Ended earlyNCT06987968
What this trial is testing

See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy

Who this might be right for
Hepatic EncephalopathyAcute on Chronic Liver Failure (ACLF)Decompensated Cirrhosis
Genfit 3
Not applicableLooking for participantsNCT06805695
What this trial is testing

Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseUrea Cycle Disorders, Inborn
iECURE, Inc. 13
Not applicableLooking for participantsNCT06953505
What this trial is testing

At Home Ammonia Monitoring of Inborn Errors of Ammonia Metabolism

Who this might be right for
Urea Cycle DisordersOrganic AcidemiasFatty Acid Oxidation Disorder+1 more
Sequitur Health Corp. 30
Not applicableStudy completedNCT00472732
What this trial is testing

Neurologic Injuries in Adults With Urea Cycle Disorders

Who this might be right for
Brain Diseases, Metabolic, InbornUrea Cycle DisorderOrnithine Transcarbamylase Deficiency
Andrea Gropman 46
Not applicableStudy completedNCT04269122
What this trial is testing

Assess Plasma Ammonia Time-Normalized Area Under the Curve and Rate of Ureagenesis in Healthy Adult Subjects

Who this might be right for
Ornithine Transcarbamylase Deficiency
Ultragenyx Pharmaceutical Inc 120
Not applicableStudy completedNCT00931060
What this trial is testing

Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects

Who this might be right for
Liver DiseasesHepatic EncephalopathyHepatic Insufficiency
University of Aarhus 24
Testing effectiveness (Phase 2)Ended earlyNCT03933410
What this trial is testing

UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder

Who this might be right for
Urea Cycle Disorder
Kaleido Biosciences 13
Not applicableEnrolling By InvitationNCT06987604
What this trial is testing

Continuous Renal Replacement Therapy Intensity in Hyperammonemia

Who this might be right for
Acute Liver FailureAcute on Chronic Liver Failure (ACLF)Acute Kidney Injury+1 more
Hospital de Clinicas de Porto Alegre 152
Not applicableLooking for participantsNCT06115148
What this trial is testing

Breath Analysis & Malnutrition

Who this might be right for
Malnutrition
Pennington Biomedical Research Center 12
Testing effectiveness (Phase 2)UnknownNCT02334163
What this trial is testing

The Effects of Nitazoxanide in Hepatic Encephalopathy

Who this might be right for
Hepatic Encephalopathy
Ain Shams University 36
Not applicableStudy completedNCT00424957
What this trial is testing

Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System

Who this might be right for
CirrhosisHepatic Encephalopathy
University of Aarhus 18
Large-scale testing (Phase 3)WithdrawnNCT04128462
What this trial is testing

MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function

Who this might be right for
Hepatic Encephalopathy
Mallinckrodt
Not applicableEnded earlyNCT01948427
What this trial is testing

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs)

Who this might be right for
Urea Cycle Disorder
Amgen 203
Large-scale testing (Phase 3)UnknownNCT03021876
What this trial is testing

L-carnitine Corrects Ammonia Metabolism in Hepatectomized Patients

Who this might be right for
Ammonia Metabolism
Kochi University 80
Not applicableStudy completedNCT00836420
What this trial is testing

Cerebral Microdialysis in Patients With Fulminant Hepatic Failure

Who this might be right for
Fulminant Hepatic Failure
Rigshospitalet, Denmark 50
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