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Results for “Muscle Invasive Bladder Cancer (MIBC)”

57 trials

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Showing 20 of 57 results

Testing effectiveness (Phase 2)UnknownNCT04813107
What this trial is testing

Evaluate the Safety and Efficacy of Oral APL-1202 in Combination With Tislelizumab Compared to Tislelizumab Alone as Neoadjuvant Therapy in Patients With Muscle Invasive Bladder Cancer

Who this might be right for
Muscle Invasive Bladder Cancer
Jiangsu Yahong Meditech Co., Ltd aka Asieris 79
Large-scale testing (Phase 3)Looking for participantsNCT07067749
What this trial is testing

Treatment Expedition With MRI Processing and Optimization for Muscle Invasive Bladder Cancer

Who this might be right for
Bladder (Urothelial, Transitional Cell) CancerBladder Cancer Requiring CystectomyBladder Carcinoma+2 more
University of Rome Tor Vergata 92
Not applicableStudy completedNCT06337591
What this trial is testing

Diagnostic Performance of the Vesical Imaging-Reporting and Data System (VI-RADS) in Detecting Muscle-invasive Bladder Tumour (MIBC) in Clinical Practice: Comparison With Transurethral Resection of Bladder Cancer (TURB) and Evaluation of Diagnostic Accuracy According to Tumour Location

Who this might be right for
Bladder Cancer
Istituto Nazionale di Ricovero e Cura per Anziani 20
Testing effectiveness (Phase 2)Looking for participantsNCT07296705
What this trial is testing

Neoadjuvant Zanidatamab + Tislelizumab + Chemotherapy for Selective Bladder Preservation in HER2-Positive MIBC

Who this might be right for
Muscle Invasive Bladder Cancer (MIBC)
Fujian Medical University Union Hospital 25
Not applicableUnknownNCT05767528
What this trial is testing

Clinical Study of Neoadjuvant Therapy Outcome Prediction of Muscle-invasive Bladder Cancer Based on PTC Drug Sensitivity Detection

Who this might be right for
Muscle-Invasive Bladder Carcinoma
Chinese PLA General Hospital 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06623162
What this trial is testing

Sasanlimab As Maintenance Treatment Based on Clinical Response to Neoadjuvant Treatment in Molecularly Categorized Muscle Invasive Bladder Cancer Patients

Who this might be right for
MibcMuscle Invasive Bladder Cancer
Fundación de investigación HM 70
Large-scale testing (Phase 3)Study completedNCT04700124
What this trial is testing

Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-Eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

Who this might be right for
Bladder Cancer
Merck Sharp & Dohme LLC 808
Testing effectiveness (Phase 2)Study completedNCT03294304
What this trial is testing

BLASST-1 (Bladder Cancer Signal Seeking Trial): Nivolumab, Gemcitabine, and Cisplatin in Treatment of Muscle Invasive Bladder Cancer (MIBC) Undergoing Cystectomy

Who this might be right for
Muscle Invasive Bladder Cancer
Masonic Cancer Center, University of Minnesota 43
Testing effectiveness (Phase 2)Ended earlyNCT03288545
What this trial is testing

Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

Who this might be right for
Carcinoma, Transitional CellUrinary Bladder NeoplasmsUrologic Neoplasms+4 more
Astellas Pharma Global Development, Inc. 348
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07201675
What this trial is testing

Vedisertib (RC48/ADC) Combined With Toripalimab in Bladder-preserving Treatment

Who this might be right for
Muscle Invasive Bladder Cancer (MIBC)
Qilu Hospital of Shandong University 59
Early research (Phase 1)Active Not RecruitingNCT02546661
What this trial is testing

Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer

Who this might be right for
Muscle Invasive Bladder Cancer
AstraZeneca 117
Testing effectiveness (Phase 2)Looking for participantsNCT06341400
What this trial is testing

RC48 Combined with Toripalimab As Neoadjuvant Therapy for Cisplatin Ineligible MIBC Patients

Who this might be right for
Bladder CancerMuscle-Invasive Bladder Carcinoma
Zhujiang Hospital 55
Early research (Phase 1)Study completedNCT04610671
What this trial is testing

Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With MIBC

Who this might be right for
Muscle-Invasive Bladder CarcinomaBladder Cancer
H. Lee Moffitt Cancer Center and Research Institute 21
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06957561
What this trial is testing

Disitamab Vedotin Combined With Ivonescimab in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer

Who this might be right for
Bladder CancerMuscle-invasive Bladder Cancer
Sun Yat-sen University 30
Large-scale testing (Phase 3)Active Not RecruitingNCT03732677
What this trial is testing

Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

Who this might be right for
Muscle Invasive Bladder Cancer
AstraZeneca 1,063
Not applicableNot Yet RecruitingNCT07529639
What this trial is testing

Tumor Budding and T1 Substaging in Urothelial Bladder Cancer

Who this might be right for
Urothelial Bladder CarcinomaBladder CarcinomaNon-Muscle-Invasive Bladder Cancer (NMIBC)+1 more
Assiut University 100
Not applicableStudy completedNCT02203136
What this trial is testing

Improving Clinical Staging for Muscle Invasive Bladder Cancer Through Molecular Profiling and Improved Imaging

Who this might be right for
Bladder Cancer
M.D. Anderson Cancer Center 16
Not applicableNot Yet RecruitingNCT07525349
What this trial is testing

Immune-Stromal Landscape in Muscle-Invasive Bladder Cancer

Who this might be right for
Muscle-Invasive Bladder CarcinomaUrothelial Carcinoma (UC)Bladder Cancer+2 more
Assiut University 100
Testing effectiveness (Phase 2)Looking for participantsNCT06511648
What this trial is testing

Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations

Who this might be right for
Muscle-invasive Bladder Cancer
Spanish Oncology Genito-Urinary Group 90
Large-scale testing (Phase 3)Looking for participantsNCT06879145
What this trial is testing

Clinical Study on the Treatment of MIBC Patients With SHR-A2102 Injection Combined With Adebrelimab (SHR-1316)

Who this might be right for
Muscular Invasive Bladder Cancer (MIBC)
Suzhou Suncadia Biopharmaceuticals Co., Ltd. 840
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