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Results for “Newly Diagnosed Primary Amyloidosis”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Looking for participantsNCT07224672
What this trial is testing

Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants With Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis

Who this might be right for
Amyloidosis
GlaxoSmithKline 60
Testing effectiveness (Phase 2)Study completedNCT00089167
What this trial is testing

Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis

Who this might be right for
Multiple Myeloma and Plasma Cell Neoplasm
Memorial Sloan Kettering Cancer Center
Large-scale testing (Phase 3)Not Yet RecruitingNCT07793422
What this trial is testing

Study to Evaluate Change in Disease Activity and Adverse Events of Subcutaneous Etentamig Compared With Daratumumab Plus Cyclophosphamide Plus Bortezomib Plus Dexamethasone (Dara-CyBorD) in Adults With Amyloid Light Chain (AL) Amyloidosis

Who this might be right for
Amyloid Light Chain (AL) Amyloidosis
AbbVie 370
Large-scale testing (Phase 3)Study completedNCT03201965
What this trial is testing

Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

Who this might be right for
Amyloidosis
Janssen Research & Development, LLC 416
Testing effectiveness (Phase 2)Study completedNCT00981708
What this trial is testing

Lenalidomide, Dexamethasone and Cyclophosphamide in Amyloidosis (AL)

Who this might be right for
Amyloidosis
University of Athens 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07055724
What this trial is testing

Study of Eque-cel CAR-T Therapy in Newly Diagnosed Severe AL Amyloidosis

Who this might be right for
AL Amyloidosis
Nanjing IASO Biotechnology Co., Ltd. 17
Early research (Phase 1)Study completedNCT03283917
What this trial is testing

Daratumumab, Ixazomib, and Dexamethasone in AL Amyloidosis

Who this might be right for
Newly Diagnosed Primary AmyloidosisRecurrent Primary AmyloidosisRefractory Primary Amyloidosis
M.D. Anderson Cancer Center 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT05996406
What this trial is testing

Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis with Translocation (11;14)

Who this might be right for
Light Chain (AL) AmyloidosisCCND1 TranslocationVenetoclax
Peking Union Medical College Hospital 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT06629818
What this trial is testing

Daratumumab Combined With Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis With Translocation (11;14)

Who this might be right for
Light Chain (AL) Amyloidosis
Peking Union Medical College Hospital 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07524634
What this trial is testing

Dose Schedule Study of BCMA Bispecific Antibody, Elranatamab, for Newly Diagnosed Immunoglobulin Light Chain (AL) Amyloidosis

Who this might be right for
Amyloid Light-chain Amyloidosis
Case Comprehensive Cancer Center 64
Early research (Phase 1)Looking for participantsNCT06768489
What this trial is testing

JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma

Who this might be right for
Multiple MyelomaSmoldering Multiple MyelomaImmunoglobulin Light-chain Amyloidosis
Janssen Research & Development, LLC 240
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07687004
What this trial is testing

Sonrotoclax and BCMA Bispecific Antibody in Newly Diagnosed Systemic AL Amyloidosis Based on t(11;14) Genetic Stratification

Who this might be right for
Multiple Myeloma (MM)
Institute of Hematology & Blood Diseases Hospital, China 50
Testing effectiveness (Phase 2)Study completedNCT00621400
What this trial is testing

Lenalidomide in Combination With Melphalan and Dexamethasone in Newly-diagnosed Light-chain (AL)-Amyloidosis

Who this might be right for
Amyloidosis
Nantes University Hospital 27
Testing effectiveness (Phase 2)Study completedNCT01194791
What this trial is testing

Lendexal in Patients With Primary Systemic Amyloidosis (AL) Newly Diagnosed

Who this might be right for
Primary Systemic Amyloidosis
PETHEMA Foundation 30
Testing effectiveness (Phase 2)Study completedNCT03236792
What this trial is testing

Ixazomib In Combination With Cyclophosphamide And Dexamethasone for Newly Diagnosed AL Amyloidosis

Who this might be right for
AL Amyloidosis
Icahn School of Medicine at Mount Sinai 28
Not applicableWithdrawnNCT06769555
What this trial is testing

BCMA/CD3 BiTE for RRAL or NDAL Amyloidosis With Insufficient Depth of Hematologic Response After Induction Therapy

Who this might be right for
AL Amyloidosis
Institute of Hematology & Blood Diseases Hospital, China
Testing effectiveness (Phase 2)Looking for participantsNCT07638683
What this trial is testing

A Phase II Study to Evaluate the Efficacy and Safety of Teclistamab in Combination With Daratumumab (Tec-Dara) in Newly Diagnosed Multiple Myeloma With Concurrent Light Chain Amyloidosis (MM+AL).

Who this might be right for
Multiple MyelomaAL Amyloidosis
Shanghai Zhongshan Hospital 30
Not applicableUnknownNCT06455748
What this trial is testing

Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study

Who this might be right for
Amyloid Light-chain Amyloidosis
Yongyong MA 20
Early research (Phase 1)Ended earlyNCT01807286
What this trial is testing

Pomalidomide With Melphalan and Dexamethasone for Untreated Systemic AL Amyloidosis

Who this might be right for
Myeloma
M.D. Anderson Cancer Center 3
Large-scale testing (Phase 3)Not Yet RecruitingNCT07709715
What this trial is testing

Phase 3 Study to Evaluate the Efficacy and Safety of NXC-201 Compared With Daratumumab With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) in Newly Diagnosed Systemic AL Amyloidosis

Who this might be right for
Light Chain (AL) Amyloidosis
Nexcella Inc. 260
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