Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Very High Risk Prostate Carcinoma”

26 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 26 results

Testing effectiveness (Phase 2)WithdrawnNCT04020094
What this trial is testing

Perioperative Atezolizumab With MVA-BN-Brachyury and PROSTVAC For Intermediate-Risk And High-Risk Localized Prostate Cancer

Who this might be right for
Prostate Adenocarcinoma
University of Utah
Early research (Phase 1)Looking for participantsNCT07054346
What this trial is testing

Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617

Who this might be right for
Prostate CancerProstate Cancer (Diagnosis)High-risk Prostate Cancer+2 more
Thomas Hope 45
Not applicableStudy completedNCT02155998
What this trial is testing

Non-Interventional Study PREVENT

Who this might be right for
Postoperative or Postradiation Adjuvant Androgen Deprivation Therapy in Locally Advanced Prostate Cancer (High and Very High Risk) Patients
AstraZeneca 200
Large-scale testing (Phase 3)Active Not RecruitingNCT02799706
What this trial is testing

Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer

Who this might be right for
Prostate Cancer
European Organisation for Research and Treatment of Cancer - EORTC 885
Testing effectiveness (Phase 2)UnknownNCT06029036
What this trial is testing

A Phase II Neoadjuvant Study of Darolutamide Plus ADT in Men With Localized Prostate Cancer

Who this might be right for
Prostate Cancer
Peking University First Hospital 53
Not applicableLooking for participantsNCT06220435
What this trial is testing

Tumor-directed Radiation Therapy for Patients With the Highest Risk Category of Localized Prostate Cancer

Who this might be right for
Prostate Cancer
Region Skane 76
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07291557
What this trial is testing

PSMA-PET Directed Radiation Therapy for High-Risk Prostate Cancer

Who this might be right for
Prostate Cancer
AHS Cancer Control Alberta 250
Testing effectiveness (Phase 2)Active Not RecruitingNCT04465500
What this trial is testing

EBRT and HDR Brachytherapy for Unfavorable-intermediate, High, and Very High-risk Prostate Cancer

Who this might be right for
Prostate CancerProstate Adenocarcinoma
University of Virginia 60
Not applicableUnknownNCT03340272
What this trial is testing

PROspective Multicenter Observational Study on Elective Pelvic Nodes Irradiation.

Who this might be right for
Intermediate Risk Prostate CancerHigh Risk Prostate Cancer
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT07751159
What this trial is testing

Radiation Therapy Approaches for People With Prostate Cancer

Who this might be right for
Prostate Cancer PatientsNon-metastatic Prostate CancerHigh Risk Prostate Cancer
Memorial Sloan Kettering Cancer Center 126
Large-scale testing (Phase 3)Active Not RecruitingNCT06235151
What this trial is testing

Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

Who this might be right for
Prostate CancerProstate Adenocarcinoma
Curium US LLC 439
Testing effectiveness (Phase 2)Looking for participantsNCT06499870
What this trial is testing

Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

Who this might be right for
Prostate Adenocarcinoma
Sean Sachdev 50
Testing effectiveness (Phase 2)Ended earlyNCT06388369
What this trial is testing

Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer

Who this might be right for
Very High Risk Prostate Carcinoma
University Hospital, Essen 1
Not applicableLooking for participantsNCT02971358
What this trial is testing

Safety and Early Efficacy of Radical Prostatectomy for Newly Diagnosed Very High Risk Locally Advanced and Oligometastatic Prostate Cancer

Who this might be right for
Locally Advanced and Metastatic Prostate Cancer
Medical University of Vienna 200
Testing effectiveness (Phase 2)UnknownNCT05376722
What this trial is testing

Pamiparib Combined With Abiraterone Acetate in Neoadjuvant Treatment of Prostate Cancer

Who this might be right for
Neoadjuvant Therapy
Hongqian Guo 30
Testing effectiveness (Phase 2)UnknownNCT05249712
What this trial is testing

Efficacy and Safety of Darolutamide Combined With ADT in High-risk/Very High-risk Localized Prostate Cancer

Who this might be right for
Prostate Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 30
Large-scale testing (Phase 3)Looking for participantsNCT06650579
What this trial is testing

REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial

Who this might be right for
Recurrent Prostate CarcinomaStage III Prostate Cancer AJCC v8Stage IVA Prostate Cancer AJCC v8
Emory University 72
Large-scale testing (Phase 3)Active Not RecruitingNCT04136353
What this trial is testing

Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate

Who this might be right for
Prostate Cancer
University of Sydney 1,100
Testing effectiveness (Phase 2)UnknownNCT04869371
What this trial is testing

Androgen Deprivation Therapy Combined With Docetaxel for High Risk Prostate Cancer

Who this might be right for
Neoadjuvant Therapy \ High Risk Prostate Cancer \ Docetaxel
Hongqian Guo 75
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07476677
What this trial is testing

Darolutamide ± ADT as Neoadjuvant Therapy in High-Risk/Very High-Risk Localized Prostate Cancer

Who this might be right for
Prostate Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 60
Next Page