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Results for “Interleukin-1beta”

56 trials

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Showing 20 of 56 results

Testing effectiveness (Phase 2)Study completedNCT02888080
What this trial is testing

Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Patients With Pulmonary Sarcoidosis

Who this might be right for
Pulmonary Sarcoidosis
Novartis Pharmaceuticals 40
Not applicableStudy completedNCT03453476
What this trial is testing

Effect of Photodynamic Therapy on Gingival Crevicular Cytokines in Periodontitis Patients

Who this might be right for
Periodontitis, AdultPeriodontal PocketPeriodontitis+1 more
National University of Singapore 51
Not applicableStudy completedNCT06295666
What this trial is testing

Gingival Crevicular Fluid (GCF) Bactericidal Permeability Protein (BPI) and Interleukin (IL)-1 Beta

Who this might be right for
PeriodontitisGingival Crevicular FluidInterleukin 1-beta+1 more
Akdeniz University 100
Early research (Phase 1)Study completedNCT02667639
What this trial is testing

Pharmacokinetics and Pharmacodynamics of RPH-104 in Healthy Subjects

Who this might be right for
Healthy
R-Pharm 35
Not applicableStudy completedNCT06786910
What this trial is testing

Effect on Cytokines IL-1ß, TNF-α, IL-4, and Total Bacterial Load of a Composition Comprising Olive Oil, Trimethylglycine and Xylitol Delivered as a Toothpaste

Who this might be right for
InflammationInterleukin-1betaTNF-α+5 more
Mucosa Innovations, S.L. 26
Not applicableStudy completedNCT04070001
What this trial is testing

The Effects of Ibuprofen and Laser on Orthodontic Pain

Who this might be right for
Crowding, Tooth
Yeşim KAYA 60
Testing effectiveness (Phase 2)Study completedNCT01302795
What this trial is testing

Canakinumab for Pyoderma Gangrenosum

Who this might be right for
Pyoderma Gangrenosum
University of Zurich 5
Testing effectiveness (Phase 2)Study completedNCT00504595
What this trial is testing

Safety and Efficacy of ACZ885 in Adult Patients With Established Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Novartis 80
Early research (Phase 1)Study completedNCT00214851
What this trial is testing

The Use of Kineret (Anakinra) in the Treatment of Familial Cold Urticaria

Who this might be right for
Familial Cold Urticaria
Nova Scotia Health Authority 8
Testing effectiveness (Phase 2)Study completedNCT01276522
What this trial is testing

Efficacy and Safety of Canakinumab in Schnitzler Syndrome

Who this might be right for
Schnitzler Syndrome
Radboud University Medical Center 8
Testing effectiveness (Phase 2)Study completedNCT00424346
What this trial is testing

Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Novartis 274
Testing effectiveness (Phase 2)UnknownNCT00928876
What this trial is testing

Interleukin-1 Receptor Antagonist and Insulin Sensitivity

Who this might be right for
Diabetes Mellitus, Type 2Insulin Resistance
Radboud University Medical Center 12
Testing effectiveness (Phase 2)Study completedNCT00487708
What this trial is testing

Safety, Efficacy, Pharmacokinetics, Pharmacodynamics of ACZ885 in Patients With NALP3 Mutations and Clinical Symptoms

Who this might be right for
NALP3 Mutation
Novartis Pharmaceuticals 34
Large-scale testing (Phase 3)Ended earlyNCT00770601
What this trial is testing

Canakinumab to Treat Neonatal-Onset Multisystem Inflammatory Disease

Who this might be right for
NOMIDCINCA Syndrome
Novartis Pharmaceuticals 7
Testing effectiveness (Phase 2)Study completedNCT00487825
What this trial is testing

Safety and Efficacy of Intravenous ACZ885 and Oral Methotrexate Therapy in Patients With Early Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Novartis 78
Post-approval studies (Phase 4)Study completedNCT01538927
What this trial is testing

Effect of Fibrin Sealant on Early Wound Healing

Who this might be right for
Periodontitis
Chhattisgarh Dental College and Research Institute 15
Not applicableNot Yet RecruitingNCT07388160
What this trial is testing

Neuroinflammatory Biomarkers After General Anesthesia: A Comparison Study

Who this might be right for
AnesthesiaNeuroinflammationCognitive Disorders
University of Health Sciences Balikesir Hospital Eduation and Research 160
Large-scale testing (Phase 3)Study completedNCT02227420
What this trial is testing

Effects of IL-1 Beta on the HPA-axis in Obese Persons

Who this might be right for
Metabolic SyndromeHypersecretion; Cortisol
University Hospital, Basel, Switzerland 76
Large-scale testing (Phase 3)Study completedNCT05498467
What this trial is testing

The Role of Interleukin-1 Beta Targeted Therapy for Patients Suffering From Allergic Contact Dermatitis

Who this might be right for
Allergic Contact Dermatitis
Herlev and Gentofte Hospital 20
Large-scale testing (Phase 3)Study completedNCT00991146
What this trial is testing

Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase

Who this might be right for
Cryopyrin-associated Periodic SyndromesFamilial Cold Autoinflammatory SyndromeMuckle-Wells Syndrome+1 more
Novartis Pharmaceuticals 19
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