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Results for “Mutation Abnormality”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT06452277
What this trial is testing

Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Who this might be right for
Advanced Non-small Cell Lung Cancer, HER2 Mutation
Bayer 555
Testing effectiveness (Phase 2)UnknownNCT01131429
What this trial is testing

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

Who this might be right for
Neoplasms, LungCarcinoma, Non-Small Cell LungDrug Therapy+1 more
Chinese PLA General Hospital 60
Not applicableStudy completedNCT04976439
What this trial is testing

Patogenic Mutation in 5 Genes

Who this might be right for
Colorectal CancerAPC Gene MutationTP53 Gene Mutation+3 more
Dr Cipto Mangunkusumo General Hospital 22
Testing effectiveness (Phase 2)Ended earlyNCT03605069
What this trial is testing

A Double-blind, Randomized, Intra-subject Placebo-controlled, Multicenter, Multiple Dose Study, Evaluating Safety, Proof of Mechanism, Preliminary Efficacy and Systemic Exposure in Subjects With Confirmed DDEB or RDEB Diagnosis With One or More Pathogenic Mutations in Exon 73 in the COL7A1 Gene

Who this might be right for
Epidermolysis Bullosa Dystrophica, RecessiveEpidermolysis Bullosa Dystrophica, Dominant
Phoenicis Therapeutics 2
Not applicableStudy completedNCT04105153
What this trial is testing

Real-world Analysis of Workup at Disease Progression and Implementation of Osimertinib for EGFR+ NSCLC

Who this might be right for
EGFR Positive Non-small Cell Lung Cancer
Thoraxklinik-Heidelberg gGmbH 400
Not applicableLooking for participantsNCT04095195
What this trial is testing

Registry of Subjects at Risk of Pancreatic Cancer

Who this might be right for
Familial Pancreatic CancerBRCA1 MutationBRCA2 Mutation+4 more
Associazione Italiana per lo Studio del Pancreas 1,000
Large-scale testing (Phase 3)Active Not RecruitingNCT05269394
What this trial is testing

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Who this might be right for
Alzheimers DiseaseDementiaAlzheimers Disease, Familial
Washington University School of Medicine 197
Early research (Phase 1)Ended earlyNCT04250051
What this trial is testing

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic SyndromeRecurrent Myeloproliferative Neoplasm+5 more
Northwestern University 2
Not applicableStudy completedNCT01942005
What this trial is testing

EVER/TMC Mutation as Marker of the Risk of Cutaneous Carcinoma in Immunosuppressed Patients

Who this might be right for
ImmunosuppressionNeoplasm
Andreas Arnold 144
Not applicableUnknownNCT01960231
What this trial is testing

The Effect of ß-cell Specific Glucokinase Mutation on Glucose Homeostasis and Insulin Secretion in a MODY-2 Family

Who this might be right for
MODY-2 Diabetes
Sheba Medical Center 30
Early research (Phase 1)Ended earlyNCT05226507
What this trial is testing

Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Who this might be right for
Advanced Solid TumorOvarian CancerOvarian Clear Cell Carcinoma+5 more
Nuvectis Pharma, Inc. 45
Testing effectiveness (Phase 2)Looking for participantsNCT07405801
What this trial is testing

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 80
Not applicableUnknownNCT05102994
What this trial is testing

Mutation Detection for VRL

Who this might be right for
Vitreoretinal LymphomaUveitis
Sun Yat-sen University 40
Large-scale testing (Phase 3)Study completedNCT03285802
What this trial is testing

Treatment Plan for an Individual Patient With Recurrent Uterine Papillary Serous Carcinoma (UPSC) With PIK3CA Gene Mutation

Who this might be right for
Uterine Cancer
Greater Baltimore Medical Center 1
Early research (Phase 1)Study completedNCT06221475
What this trial is testing

Learn How BAY2927088 is Taken up and Handled by the Body in Healthy Male Participants

Who this might be right for
Advanced Non-small Cell Lung CancerEGFR MutationHER2 Mutation+1 more
Bayer 8
Testing effectiveness (Phase 2)UnknownNCT02535507
What this trial is testing

Efficacy and Safety of Pyrotinib in Patients With HER2 Mutation Advanced Non-Small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Tongji University 40
Testing effectiveness (Phase 2)Temporarily pausedNCT04846036
What this trial is testing

The KHENERGYC Study

Who this might be right for
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMELAS+1 more
Khondrion BV 24
Early research (Phase 1)Study completedNCT06117371
What this trial is testing

Study of BEBT-607 Tablets in The Treatment of Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

Who this might be right for
Advanced or Metastatic Solid TumorKRAS G12C Mutation
BeBetter Med Inc 11
Testing effectiveness (Phase 2)UnknownNCT05327621
What this trial is testing

Pamiparib in mCRPC With HRD or BRCA1/2 Mutation

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
Sun Yat-sen University 50
Not applicableWithdrawnNCT05257707
What this trial is testing

Molecular Markers in Cancers and Precancers (MOCA)

Who this might be right for
CancerPrecancerous LesionHealthy
Centre Hospitalier Universitaire de Besancon
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